Skip to main content

Articles

Page 251 of 330

  1. Glucocorticoids such as prednisolone and dexamethasone are critical drugs used in multi-agent chemotherapy protocols used to treat acute lymphoblastic leukemia (ALL), and response to glucocorticoids is highly ...

    Authors: Vivek A Bhadri, Mark J Cowley, Warren Kaplan, Toby N Trahair and Richard B Lock
    Citation: BMC Genomics 2011 12:565
  2. To complement next-generation sequencing technologies, there is a pressing need for efficient pre-sequencing capture methods with reduced costs and DNA requirement. The Alu family of short interspersed nucleot...

    Authors: Lingling Mei, Xiaofan Ding, Shui-Ying Tsang, Frank W Pun, Siu-Kin Ng, Jianfeng Yang, Cunyou Zhao, Dezhi Li, Weiqing Wan, Chi-Hung Yu, Tze-Ching Tan, Wai-Sang Poon, Gilberto Ka-Kit Leung, Ho-Keung Ng, Liwei Zhang and Hong Xue
    Citation: BMC Genomics 2011 12:564
  3. There is only a limited understanding of the relation between copy number and expression for mammalian genes. We fine mapped cis and trans regulatory loci due to copy number change for essentially all genes using...

    Authors: Richard T Wang, Sangtae Ahn, Christopher C Park, Arshad H Khan, Kenneth Lange and Desmond J Smith
    Citation: BMC Genomics 2011 12:562
  4. Mammalian olfactory receptors (ORs) are subject to a remarkable but poorly understood regime of transcriptional regulation, whereby individual olfactory neurons each express only one allele of a single member ...

    Authors: Janet M Young, Ralf M Luche and Barbara J Trask
    Citation: BMC Genomics 2011 12:561
  5. Alu repeats, which account for ~10% of the human genome, were originally considered to be junk DNA. Recent studies, however, suggest that they may contain transcription factor binding sites and hence possibly ...

    Authors: Eugene Bolotin, Karthikeyani Chellappa, Wendy Hwang-Verslues, Jake M Schnabl, Chuhu Yang and Frances M Sladek
    Citation: BMC Genomics 2011 12:560
  6. One of the goals of livestock genomics research is to identify the genetic differences responsible for variation in phenotypic traits, particularly those of economic importance. Characterizing the genetic vari...

    Authors: Paul Stothard, Jung-Woo Choi, Urmila Basu, Jennifer M Sumner-Thomson, Yan Meng, Xiaoping Liao and Stephen S Moore
    Citation: BMC Genomics 2011 12:559
  7. Integration of genomic variation with phenotypic information is an effective approach for uncovering genotype-phenotype associations. This requires an accurate identification of the different types of variatio...

    Authors: Bujie Zhan, João Fadista, Bo Thomsen, Jakob Hedegaard, Frank Panitz and Christian Bendixen
    Citation: BMC Genomics 2011 12:557
  8. Orange-spotted grouper (Epinephelus coioides) is an economically important marine fish cultured in China and Southeast Asian countries. The emergence of infectious viral diseases, including iridovirus and betanod...

    Authors: Youhua Huang, Xiaohong Huang, Yang Yan, Jia Cai, Zhengliang Ouyang, Huachun Cui, Peiran Wang and Qiwei Qin
    Citation: BMC Genomics 2011 12:556
  9. A paucity of information on biological sex-specific differences in cardiac gene expression in response to diet has prompted this present nutrigenomics investigation.

    Authors: Kate S Collison, Marya Z Zaidi, Zakia Maqbool, Soad M Saleh, Angela Inglis, Nadine J Makhoul, Razan Bakheet, Mohammed Shoukri and Futwan A Al-Mohanna
    Citation: BMC Genomics 2011 12:555
  10. Comparative studies of amniotes have been hindered by a dearth of reptilian molecular sequences. With the genomic assembly of the green anole, Anolis carolinensis available, non-avian reptilian genes can now be c...

    Authors: Kenro Kusumi, Rob J Kulathinal, Arhat Abzhanov, Stephane Boissinot, Nicholas G Crawford, Brant C Faircloth, Travis C Glenn, Daniel E Janes, Jonathan B Losos, Douglas B Menke, Steven Poe, Thomas J Sanger, Christopher J Schneider, Jessica Stapley, Juli Wade and Jeanne Wilson-Rawls
    Citation: BMC Genomics 2011 12:554
  11. Bald cypress (Taxodium distichum var. distichum) is a coniferous tree of tremendous ecological and economic importance. It is a member of the family Cupressaceae which also includes cypresses, redwoods, sequoias,...

    Authors: Wenxuan Liu, Supaphan Thummasuwan, Sunish K Sehgal, Philippe Chouvarine and Daniel G Peterson
    Citation: BMC Genomics 2011 12:553
  12. Although RNA-seq greatly advances our understanding of complex transcriptome landscapes, such as those found in mammals, complete RNA-seq studies in livestock and in particular in the pig are still lacking. He...

    Authors: Anna Esteve-Codina, Robert Kofler, Nicola Palmieri, Giovanni Bussotti, Cedric Notredame and Miguel Pérez-Enciso
    Citation: BMC Genomics 2011 12:552
  13. Developing sympathetic neurons depend on nerve growth factor (NGF) for survival and die by apoptosis after NGF withdrawal. This process requires de novo gene expression but only a small number of genes induced by...

    Authors: Mark Kristiansen, Francesca Menghi, Rosie Hughes, Mike Hubank and Jonathan Ham
    Citation: BMC Genomics 2011 12:551
  14. Although the high mobility group A1 (HMGA1) gene is widely overexpressed in diverse cancers and portends a poor prognosis in some tumors, the molecular mechanisms that mediate its role in transformation have rema...

    Authors: Andrew Schuldenfrei, Amy Belton, Jeanne Kowalski, C Conover Talbot Jr, Francescopaolo Di Cello, Weijie Poh, Hua-Ling Tsai, Sandeep N Shah, Tait H Huso, David L Huso and Linda MS Resar
    Citation: BMC Genomics 2011 12:549
  15. The genetics of transcript-level variation is an exciting field that has recently given rise to many studies. Genetical genomics studies have mainly focused on cell lines, blood cells or adipose tissues, from ...

    Authors: Laurence Liaubet, Valérie Lobjois, Thomas Faraut, Aurélie Tircazes, Francis Benne, Nathalie Iannuccelli, José Pires, Jérome Glénisson, Annie Robic, Pascale Le Roy, Magali SanCristobal and Pierre Cherel
    Citation: BMC Genomics 2011 12:548
  16. MicroRNAs (miRNAs) are a class of small regulatory RNAs that target sequences in messenger RNAs (mRNAs) to inhibit their protein output. Dissecting the complexities of miRNA function continues to prove challen...

    Authors: Jos B Poell, Rick J van Haastert, Francesco Cerisoli, Anne S Bolijn, Lisette M Timmer, Begoña Diosdado-Calvo, Gerrit A Meijer, Andre AFL van Puijenbroek, Eugene Berezikov, Roel QJ Schaapveld and Edwin Cuppen
    Citation: BMC Genomics 2011 12:546
  17. Corynebacterium variabile is part of the complex microflora on the surface of smear-ripened cheeses and contributes to the development of flavor and textural properties during cheese ripening. Still little is kno...

    Authors: Jasmin Schröder, Irena Maus, Eva Trost and Andreas Tauch
    Citation: BMC Genomics 2011 12:545
  18. Initiation and elongation of RNA polymerase II (RNAPII) transcription is regulated by both DNA sequence and chromatin signals. Recent breakthroughs make it possible to measure the chromatin state and activity ...

    Authors: Yun Chen, Mette Jørgensen, Raivo Kolde, Xiaobei Zhao, Brian Parker, Eivind Valen, Jiayu Wen and Albin Sandelin
    Citation: BMC Genomics 2011 12:544
  19. Small nucleolar RNAs (snoRNAs) are a large group of non-coding RNAs (ncRNAs) that mainly guide 2'-O-methylation (C/D RNAs) and pseudouridylation (H/ACA RNAs) of ribosomal RNAs. The pattern of rRNA modification...

    Authors: Julia A Makarova and Dmitri A Kramerov
    Citation: BMC Genomics 2011 12:543
  20. Amoebae are phagocytic protists where genetic exchanges might take place between amoeba-resistant bacteria. These amoebal pathogens are able to escape the phagocytic behaviour of their host. They belong to dif...

    Authors: Gregory Gimenez, Claire Bertelli, Claire Moliner, Catherine Robert, Didier Raoult, Pierre-Edouard Fournier and Gilbert Greub
    Citation: BMC Genomics 2011 12:542
  21. Interactions between fish and pathogens, that may be harmless under natural conditions, often result in serious diseases in aquaculture systems. This is especially important due to the fact that the strains us...

    Authors: Silvia T Rodríguez-Ramilo, Miguel A Toro, Carmen Bouza, Miguel Hermida, Belén G Pardo, Santiago Cabaleiro, Paulino Martínez and Jesús Fernández
    Citation: BMC Genomics 2011 12:541
  22. Bupleurum chinense DC. is a widely used traditional Chinese medicinal plant. Saikosaponins are the major bioactive constituents of B. chinense, but relatively little is known about saikosaponin biosynthesis. The ...

    Authors: Chun Sui, Jie Zhang, Jianhe Wei, Shilin Chen, Ying Li, Jiesen Xu, Yue Jin, Caixiang Xie, Zhihui Gao, Hongjiang Chen, Chengmin Yang, Zheng Zhang and Yanhong Xu
    Citation: BMC Genomics 2011 12:539
  23. In a context of climate change, phenotypic plasticity provides long-lived species, such as trees, with the means to adapt to environmental variations occurring within a single generation. In eucalyptus plantat...

    Authors: Emilie Villar, Christophe Klopp, Céline Noirot, Evandro Novaes, Matias Kirst, Christophe Plomion and Jean-Marc Gion
    Citation: BMC Genomics 2011 12:538
  24. Common carp (Cyprinus carpio), a member of Cyprinidae, is the third most important aquaculture species in the world with an annual global production of 3.4 million metric tons, accounting for nearly 14% of the al...

    Authors: Peng Xu, Jian Wang, Jintu Wang, Runzi Cui, Yan Li, Zixia Zhao, Peifeng Ji, Yan Zhang, Jiongtang Li and Xiaowen Sun
    Citation: BMC Genomics 2011 12:537
  25. Legionella pneumophila is an intracellular pathogen of environmental protozoa. When humans inhale contaminated aerosols this bacterium may cause a severe pneumonia called Legionnaires' disease. Despite the abunda...

    Authors: Laura Gomez-Valero, Christophe Rusniok, Sophie Jarraud, Benoit Vacherie, Zoé Rouy, Valerie Barbe, Claudine Medigue, Jerome Etienne and Carmen Buchrieser
    Citation: BMC Genomics 2011 12:536
  26. In the United Kingdom, the thermophilic Campylobacter species C. jejuni and C. coli are the most frequent causes of food-borne gastroenteritis in humans. While campylobacteriosis is usually a relatively mild infe...

    Authors: Aline Metris, Mark Reuter, Duncan JH Gaskin, Jozsef Baranyi and Arnoud HM van Vliet
    Citation: BMC Genomics 2011 12:535
  27. The canine Gram-negative Helicobacter bizzozeronii is one of seven species in Helicobacter heilmannii sensu lato that are detected in 0.17-2.3% of the gastric biopsies of human patients with gastric symptoms. At ...

    Authors: Thomas Schott, Pradeep K Kondadi, Marja-Liisa Hänninen and Mirko Rossi
    Citation: BMC Genomics 2011 12:534
  28. Camptotheca acuminata is a Nyssaceae plant, often called the "happy tree", which is indigenous in Southern China. C. acuminata produces the terpenoid indole alkaloid, camptothecin (CPT), which exhibits clinical e...

    Authors: Yongzhen Sun, Hongmei Luo, Ying Li, Chao Sun, Jingyuan Song, Yunyun Niu, Yingjie Zhu, Liang Dong, Aiping Lv, Enzo Tramontano and Shilin Chen
    Citation: BMC Genomics 2011 12:533
  29. Changes in transcriptional regulation underlie many of the phenotypic differences observed within and between species of bacteria. Lateral genetic transfer (LGT) can significantly impact the transcription fact...

    Authors: Elizabeth Skippington and Mark A Ragan
    Citation: BMC Genomics 2011 12:532
  30. Functional and morphological studies of tandem DNA repeats, that combine high portion of most genomes, are mostly limited due to the incomplete characterization of these genome elements. We report here a genom...

    Authors: Aleksey S Komissarov, Ekaterina V Gavrilova, Sergey Ju Demin, Alexander M Ishov and Olga I Podgornaya
    Citation: BMC Genomics 2011 12:531
  31. The deep-sea hydrothermal vent mussel Bathymodiolus azoricus harbors thiotrophic and methanotrophic symbiotic bacteria in its gills. While the symbiotic relationship between this hydrothermal mussel and these che...

    Authors: Isabelle Boutet, Raymond Ripp, Odile Lecompte, Carole Dossat, Erwan Corre, Arnaud Tanguy and François H Lallier
    Citation: BMC Genomics 2011 12:530
  32. The human placenta facilitates the exchange of nutrients, gas and waste between the fetal and maternal circulations. It also protects the fetus from the maternal immune response. Due to its role at the feto-ma...

    Authors: Boris Novakovic, Ryan K Yuen, Lavinia Gordon, Maria S Penaherrera, Andrew Sharkey, Ashley Moffett, Jeffrey M Craig, Wendy P Robinson and Richard Saffery
    Citation: BMC Genomics 2011 12:529
  33. Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disorder that can be triggered through genetic or sporadic mechanisms. MicroRNAs (miRNAs) have become a major therapeutic focus as th...

    Authors: Jannet Kocerha, Naomi Kouri, Matt Baker, NiCole Finch, Mariely DeJesus-Hernandez, John Gonzalez, Kumaravel Chidamparam, Keith A Josephs, Bradley F Boeve, Neill R Graff-Radford, Julia Crook, Dennis W Dickson and Rosa Rademakers
    Citation: BMC Genomics 2011 12:527
  34. The adaptation of pathogenic fungi to the host environment via large-scale genomic changes is a poorly characterized phenomenon. Cryptococcus neoformans is the leading cause of fungal meningoencephalitis in HIV/A...

    Authors: Guanggan Hu, Joyce Wang, Jaehyuk Choi, Won Hee Jung, Iris Liu, Anastasia P Litvintseva, Tihana Bicanic, Rajeev Aurora, Thomas G Mitchell, John R Perfect and James W Kronstad
    Citation: BMC Genomics 2011 12:526
  35. Soybean is a valuable crop that provides protein and oil. Soybean requires a large amount of nitrogen (N) to accumulate high levels of N in the seed. The yield and protein content of soybean seeds are directly...

    Authors: Qing N Hao, Xin A Zhou, Ai H Sha, Cheng Wang, Rong Zhou and Shui L Chen
    Citation: BMC Genomics 2011 12:525
  36. Di-(2-ethylhexyl)-phthalate (DEHP) is a commonly used plasticizer in polyvinylchloride (PVC) formulations and a potentially non-genotoxic carcinogen. The aim of this study was to identify genes whose level of ...

    Authors: Yann Landkocz, Pascal Poupin, Franck Atienzar and Paule Vasseur
    Citation: BMC Genomics 2011 12:524
  37. Streptococcus suis (S. suis) is a major swine pathogen and an emerging zoonotic agent. Serotypes 1, 2, 3, 7, 9, 14 and 1/2 are the most prevalent serotypes of this pathogen. However, almost all studies were carri...

    Authors: Anding Zhang, Ming Yang, Pan Hu, Jiayan Wu, Bo Chen, Yafeng Hua, Jun Yu, Huanchun Chen, Jingfa Xiao and Meilin Jin
    Citation: BMC Genomics 2011 12:523
  38. Efforts towards utilisation of diets without fish meal (FM) or fish oil (FO) in finfish aquaculture have been being made for more than two decades. Metabolic responses to substitution of fishery products have ...

    Authors: Florian Geay, Serena Ferraresso, Jose L Zambonino-Infante, Luca Bargelloni, Claire Quentel, Marc Vandeputte, Sachi Kaushik, Chantal L Cahu and David Mazurais
    Citation: BMC Genomics 2011 12:522
  39. Lupinus angustifolius L, also known as narrow-leafed lupin (NLL), is becoming an important grain legume crop that is valuable for sustainable farming and is becoming recognised as a potential human health food. R...

    Authors: Ling-Ling Gao, James K Hane, Lars G Kamphuis, Rhonda Foley, Bu-Jun Shi, Craig A Atkins and Karam B Singh
    Citation: BMC Genomics 2011 12:521
  40. The heterotrophic dinoflagellate Oxyrrhis marina is increasingly studied in experimental, ecological and evolutionary contexts. Its basal phylogenetic position within the dinoflagellates make O. marina useful for...

    Authors: Chris D Lowe, Luciane V Mello, Najma Samatar, Laura E Martin, David JS Montagnes and Phillip C Watts
    Citation: BMC Genomics 2011 12:519
  41. Common genetic variants that regulate gene expression are widely suspected to contribute to the etiology and phenotypic variability of complex diseases. Although high-throughput, microarray-based assays have b...

    Authors: Xiang Xu, Hao Wang, Min Zhu, Yue Sun, Yu Tao, Qin He, Jian Wang, Li Chen and David Saffen
    Citation: BMC Genomics 2011 12:518
  42. Eukaryotic nuclear genomes contain fragments of mitochondrial DNA called NumtS (Nuclear mitochondrial Sequences), whose mode and time of insertion, as well as their functional/structural role within the genome...

    Authors: Domenico Simone, Francesco Maria Calabrese, Martin Lang, Giuseppe Gasparre and Marcella Attimonelli
    Citation: BMC Genomics 2011 12:517
  43. Cellular function is regulated by the balance of stringently regulated amounts of mRNA. Previous reports revealed that RNA polymerase II (RNAPII), which transcribes mRNA, can be classified into the pausing sta...

    Authors: Jun Odawara, Akihito Harada, Tomohiko Yoshimi, Kazumitsu Maehara, Taro Tachibana, Seiji Okada, Koichi Akashi and Yasuyuki Ohkawa
    Citation: BMC Genomics 2011 12:516

Featured videos

View featured videos from across the BMC-series journals

Annual Journal Metrics

  • 2022 Citation Impact
    4.4 - 2-year Impact Factor
    4.7 - 5-year Impact Factor
    1.189 - SNIP (Source Normalized Impact per Paper)
    1.107 - SJR (SCImago Journal Rank)

    2023 Speed
    23 days submission to first editorial decision for all manuscripts (Median)
    137 days submission to accept (Median)

    2023 Usage
    7,167,242 downloads
    4,454 Altmetric mentions

Sign up for article alerts and news from this journal