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  1. A deficiency in phaseolin and phytohemagglutinin is associated with a near doubling of sulfur amino acid content in genetically related lines of common bean (Phaseolus vulgaris), particularly cysteine, elevated b...

    Authors: Fuqiang Yin, Agnieszka Pajak, Ralph Chapman, Andrew Sharpe, Shangzhi Huang and Frédéric Marsolais
    Citation: BMC Genomics 2011 12:268
    Content type: Research article Published on:

  2. Entamoeba histolytica and Entamoeba dispar are closely related protistan parasites but while E. histolytica can be invasive, E. dispar is completely non pathogenic. Transposable elements constitute a significant ...

    Authors: Vandana Kumari, Rahul Sharma, Vijay P Yadav, Abhishek K Gupta, Alok Bhattacharya and Sudha Bhattacharya
    Citation: BMC Genomics 2011 12:267
    Content type: Research article Published on:

  3. Cassava (Manihot esculenta Crantz) can produce cyanide, a toxic compound, without self-injury. That ability was called the cyanogenic potential (CN). This project aimed to identify quantitative trait loci (QTL) a...

    Authors: Sukhuman Whankaew, Supannee Poopear, Supanath Kanjanawattanawong, Sithichoke Tangphatsornruang, Opas Boonseng, David A Lightfoot and Kanokporn Triwitayakorn
    Citation: BMC Genomics 2011 12:266
    Content type: Research article Published on:

  4. Lentil (Lens culinaris Medik.) is a cool-season grain legume which provides a rich source of protein for human consumption. In terms of genomic resources, lentil is relatively underdeveloped, in comparison to oth...

    Authors: Sukhjiwan Kaur, Noel OI Cogan, Luke W Pembleton, Maiko Shinozuka, Keith W Savin, Michael Materne and John W Forster
    Citation: BMC Genomics 2011 12:265
    Content type: Research article Published on:

  5. Global transcriptional analysis of loblolly pine (Pinus taeda L.) is challenging due to limited molecular tools. PtGen2, a 26,496 feature cDNA microarray, was fabricated and used to assess drought-induced gene ex...

    Authors: W Walter Lorenz, Rob Alba, Yuan-Sheng Yu, John M Bordeaux, Marta Simões and Jeffrey FD Dean
    Citation: BMC Genomics 2011 12:264
    Content type: Research article Published on:

  6. Populations of Atlantic killifish (Fundulus heteroclitus) have evolved resistance to the embryotoxic effects of polychlorinated biphenyls (PCBs) and other halogenated and nonhalogenated aromatic hydrocarbons that...

    Authors: Marjorie F Oleksiak, Sibel I Karchner, Matthew J Jenny, Diana G Franks, David B Mark Welch and Mark E Hahn
    Citation: BMC Genomics 2011 12:263
    Content type: Research article Published on:

  7. Age-related gene expression patterns of Homo sapiens as well as of model organisms such as Mus musculus, Saccharomyces cerevisiae, Caenorhabditis elegans and Drosophila melanogaster are a basis for understanding ...

    Authors: Edith Hofer, Gerhard T Laschober, Matthias Hackl, Gerhard G Thallinger, Günter Lepperdinger, Johannes Grillari, Pidder Jansen-Dürr and Zlatko Trajanoski
    Citation: BMC Genomics 2011 12:262
    Content type: Database Published on:

  9. Transposable elements (TEs) are DNA sequences, present in the genome of most eukaryotic organisms that hold the key characteristic of being able to mobilize and increase their copy number within chromosomes. T...

    Authors: Rita D Fernández-Medina, Cláudio J Struchiner and José MC Ribeiro
    Citation: BMC Genomics 2011 12:260
    Content type: Research article Published on:

  10. A long term research goal of venomics, of applied importance for improving current antivenom therapy, but also for drug discovery, is to understand the pharmacological potential of venoms. Individually or comb...

    Authors: Jordi Durban, Paula Juárez, Yamileth Angulo, Bruno Lomonte, Marietta Flores-Diaz, Alberto Alape-Girón, Mahmood Sasa, Libia Sanz, José M Gutiérrez, Joaquín Dopazo, Ana Conesa and Juan J Calvete
    Citation: BMC Genomics 2011 12:259
    Content type: Research article Published on:

  12. The total number of miRNA genes in a genome, expression of which is responsible for the miRNA repertoire of an organism, is not precisely known. Moreover, the question of how new miRNA genes arise during evolu...

    Authors: Stefan Lehnert, Vladimir Kapitonov, Pushpike J Thilakarathne and Frans C Schuit
    Citation: BMC Genomics 2011 12:257
    Content type: Research article Published on:

  13. Phenotype-driven forward genetic experiments are powerful approaches for linking phenotypes to genomic elements but they still involve a laborious positional cloning process. Although sequencing of complete ge...

    Authors: Michal Mokry, Isaäc J Nijman, Anja van Dijken, Rene Benjamins, Renze Heidstra, Ben Scheres and Edwin Cuppen
    Citation: BMC Genomics 2011 12:256
    Content type: Methodology article Published on:

  14. Expansion of aquaculture is seriously limited by reductions in fish oil (FO) supply for aquafeeds. Terrestrial alternatives such as vegetable oils (VO) have been investigated and recently a strategy combining ...

    Authors: Sofia Morais, Jarunan Pratoomyot, John B Taggart, James E Bron, Derrick R Guy, J Gordon Bell and Douglas R Tocher
    Citation: BMC Genomics 2011 12:255
    Content type: Research article Published on:

  15. Phytophthora species are oomycete plant pathogens with such major social and economic impact that genome sequences have been determined for Phytophthora infestans, P. sojae and P. ramorum. Pepsin-like aspartic pr...

    Authors: John Kay, Harold JG Meijer, Arjen ten Have and Jan AL van Kan
    Citation: BMC Genomics 2011 12:254
    Content type: Research article Published on:

  16. Streptococcus suis serotype 2 (S. suis 2) is an important pathogen of pigs. S suis 2 infections have high mortality rates and are characterized by meningitis, septicemia and pneumonia. S. suis 2 is also an emergi...

    Authors: Manli Liu, Liurong Fang, Chen Tan, Tiansi Long, Huanchun Chen and Shaobo Xiao
    Citation: BMC Genomics 2011 12:253
    Content type: Research article Published on:

  17. Melon (Cucumis melo), an economically important vegetable crop, belongs to the Cucurbitaceae family which includes several other important crops such as watermelon, cucumber, and pumpkin. It has served as a model...

    Authors: Christian Clepet, Tarek Joobeur, Yi Zheng, Delphine Jublot, Mingyun Huang, Veronica Truniger, Adnane Boualem, Maria Elena Hernandez-Gonzalez, Ramon Dolcet-Sanjuan, Vitaly Portnoy, Albert Mascarell-Creus, Ana I Caño-Delgado, Nurit Katzir, Abdelhafid Bendahmane, James J Giovannoni, Miguel A Aranda…
    Citation: BMC Genomics 2011 12:252
    Content type: Research article Published on:

  18. In vitro cell systems together with omics methods represent promising alternatives to conventional animal models for toxicity testing. Transcriptomic and proteomic approaches have been widely applied in vitro but...

    Authors: Ainhoa Ruiz-Aracama, Ad Peijnenburg, Jos Kleinjans, Danyel Jennen, Joost van Delft, Caroline Hellfrisch and Arjen Lommen
    Citation: BMC Genomics 2011 12:251
    Content type: Research article Published on:

  20. Sequence related amplified polymorphism (SRAP) is commonly used to construct high density genetic maps, map genes and QTL of important agronomic traits in crops and perform genetic diversity analysis without k...

    Authors: Wei Li, Jiefu Zhang, Yanglong Mou, Jianfeng Geng, Peter BE McVetty, Shengwu Hu and Genyi Li
    Citation: BMC Genomics 2011 12:249
    Content type: Research article Published on:

  21. The domesticated silkworm, Bombyx mori, is the model insect for the order Lepidoptera, has economically important values, and has gained some representative behavioral characteristics compared to its wild ancesto...

    Authors: Bo Zhu, Miao-Miao Lou, Guan-Lin Xie, Guo-Qing Zhang, Xue-Ping Zhou, Bin Li and Gu-Lei Jin
    Citation: BMC Genomics 2011 12:248
    Content type: Research article Published on:

  22. Although second generation sequencing (2GS) technologies allow re-sequencing of previously gold-standard-sequenced genomes, whole genome shotgun sequencing and de novo assembly of large and complex eukaryotic gen...

    Authors: Daniela Schulte, Ruvini Ariyadasa, Bujun Shi, Delphine Fleury, Chris Saski, Michael Atkins, Pieter deJong, Cheng-Cang Wu, Andreas Graner, Peter Langridge and Nils Stein
    Citation: BMC Genomics 2011 12:247
    Content type: Research article Published on:

  23. Genome sequencing of barley has been delayed due to its large genome size (ca. 5,000Mbp). Among the fast sequencing systems, 454 liquid phase pyrosequencing provides the longest reads and is the most promising...

    Authors: Kazuhiro Sato, Yuka Motoi, Nami Yamaji and Hideya Yoshida
    Citation: BMC Genomics 2011 12:246
    Content type: Research article Published on:

  24. The rapid evolution of 454 GS-FLX sequencing technology has not been accompanied by a reassessment of the quality and accuracy of the sequences obtained. Current strategies for decision-making and error-correc...

    Authors: André Gilles, Emese Meglécz, Nicolas Pech, Stéphanie Ferreira, Thibaut Malausa and Jean-François Martin
    Citation: BMC Genomics 2011 12:245
    Content type: Research article Published on:

  26. In highly copy number variable (CNV) regions such as the human defensin gene locus, comprehensive assessment of sequence variations is challenging. PCR approaches are practically restricted to tiny fractions, ...

    Authors: Stefan Taudien, Karol Szafranski, Marius Felder, Marco Groth, Klaus Huse, Francesca Raffaelli, Andreas Petzold, Xinmin Zhang, Philip Rosenstiel, Jochen Hampe, Stefan Schreiber and Matthias Platzer
    Citation: BMC Genomics 2011 12:243
    Content type: Research article Published on:

  27. The black tiger shrimp (Penaeus monodon) is one of the most important aquaculture species in the world, representing the crustacean lineage which possesses the greatest species diversity among marine invertebrate...

    Authors: Shiao-Wei Huang, You-Yu Lin, En-Min You, Tze-Tze Liu, Hung-Yu Shu, Keh-Ming Wu, Shih-Feng Tsai, Chu-Fang Lo, Guang-Hsiung Kou, Gwo-Chin Ma, Ming Chen, Dongying Wu, Takashi Aoki, Ikuo Hirono and Hon-Tsen Yu
    Citation: BMC Genomics 2011 12:242
    Content type: Research article Published on:

  28. G protein-coupled receptors (GPCRs) are major players in cell communication, regulate a whole range of physiological functions during development and throughout adult life, are affected in numerous pathologica...

    Authors: Benjamin Maurel, Anne Le Digarcher, Christelle Dantec and Laurent Journot
    Citation: BMC Genomics 2011 12:241
    Content type: Methodology article Published on:

  29. Most disease-resistance (R) genes in plants encode NBS-LRR proteins and belong to one of the largest and most variable gene families among plant genomes. However, the specific evolutionary routes of NBS-LRR en...

    Authors: Alessandra F Ribas, Alberto Cenci, Marie-Christine Combes, Hervé Etienne and Philippe Lashermes
    Citation: BMC Genomics 2011 12:240
    Content type: Research article Published on:

  30. Brassica rapa is an economically important crop and a model plant for studies concerning polyploidization and the evolution of extreme morphology. The multinational B. rapa Genome Sequencing Project (BrGSP) was l...

    Authors: Yan Wang, Silong Sun, Bo Liu, Hui Wang, Jie Deng, Yongcui Liao, Qian Wang, Feng Cheng, Xiaowu Wang and Jian Wu
    Citation: BMC Genomics 2011 12:239
    Content type: Research article Published on:

  31. Studies on bacterial signal transduction systems have revealed complex networks of functional interactions, where the response regulators play a pivotal role. The AtoSC system of E. coli activates the expression ...

    Authors: Eleftherios Pilalis, Aristotelis A Chatziioannou, Asterios I Grigoroudis, Christos A Panagiotidis, Fragiskos N Kolisis and Dimitrios A Kyriakidis
    Citation: BMC Genomics 2011 12:238
    Content type: Research article Published on:

  33. BAHD acyltransferases are involved in the synthesis and elaboration of a wide variety of secondary metabolites. Previous research has shown that characterized proteins from this family fall broadly into five m...

    Authors: Lindsey K Tuominen, Virgil E Johnson and Chung-Jui Tsai
    Citation: BMC Genomics 2011 12:236
    Content type: Research article Published on:

  34. Sinorhizobium meliloti is a model system for the studies of symbiotic nitrogen fixation. An extensive polymorphism at the genetic and phenotypic level is present in natural populations of this species, especially...

    Authors: Marco Galardini, Alessio Mengoni, Matteo Brilli, Francesco Pini, Antonella Fioravanti, Susan Lucas, Alla Lapidus, Jan-Fang Cheng, Lynne Goodwin, Samuel Pitluck, Miriam Land, Loren Hauser, Tanja Woyke, Natalia Mikhailova, Natalia Ivanova, Hajnalka Daligault…
    Citation: BMC Genomics 2011 12:235
    Content type: Research article Published on:

  35. The Manila clam, Ruditapes philippinarum, is one of the major aquaculture species in the world and a potential sentinel organism for monitoring the status of marine ecosystems. However, genomic resources for R. p...

    Authors: Massimo Milan, Alessandro Coppe, Richard Reinhardt, Leonor M Cancela, Ricardo B Leite, Carlos Saavedra, Claudio Ciofi, Guido Chelazzi, Tomaso Patarnello, Stefania Bortoluzzi and Luca Bargelloni
    Citation: BMC Genomics 2011 12:234
    Content type: Research article Published on:

  36. Resistance of soybean (Glycine max L. Merr.) cultivars to populations of cyst nematode (SCN; Heterodera glycines I.) was complicated by the diversity of HG Types (biotypes), the multigenic nature of resistance an...

    Authors: Wei Chang, Limin Dong, Zizhen Wang, Haibo Hu, Yingpeng Han, Weili Teng, Hongxia Zhang, Maozu Guo and Wenbin Li
    Citation: BMC Genomics 2011 12:233
    Content type: Research article Published on:

  38. Changes in DNA methylation in the mammalian genome during development are frequent events and play major roles regulating gene expression and other developmental processes. It is necessary to identify these ev...

    Authors: Ping Liang, Fei Song, Srimoyee Ghosh, Evan Morien, Maochun Qin, Saleh Mahmood, Kyoko Fujiwara, Jun Igarashi, Hiroki Nagase and William A Held
    Citation: BMC Genomics 2011 12:231
    Content type: Research article Published on:

  39. Genomic aberrations can be used to determine cancer diagnosis and prognosis. Clinically relevant novel aberrations can be discovered using high-throughput assays such as Single Nucleotide Polymorphism (SNP) ar...

    Authors: Fabio Parisi, Stephan Ariyan, Deepak Narayan, Antonella Bacchiocchi, Kathleen Hoyt, Elaine Cheng, Fang Xu, Peining Li, Ruth Halaban and Yuval Kluger
    Citation: BMC Genomics 2011 12:230
    Content type: Research article Published on:

  40. Down syndrome (DS; trisomy 21) is the most common genetic cause of mental retardation in the human population and key molecular networks dysregulated in DS are still unknown. Many different experimental techni...

    Authors: Mireia Vilardell, Axel Rasche, Anja Thormann, Elisabeth Maschke-Dutz, Luis A Pérez-Jurado, Hans Lehrach and Ralf Herwig
    Citation: BMC Genomics 2011 12:229
    Content type: Research article Published on:

  41. The transcriptional regulatory network is considered to be built from a set of circuit patterns called network motifs. Experimental studies have provided instances where a feedforward circuit (FFC) appears wit...

    Authors: Hisakazu Iwama, Koji Murao, Hitomi Imachi and Toshihiko Ishida
    Citation: BMC Genomics 2011 12:228
    Content type: Research article Published on:

  42. The garden pea, Pisum sativum, is among the best-investigated legume plants and of significant agro-commercial relevance. Pisum sativum has a large and complex genome and accordingly few comprehensive genomic res...

    Authors: Susanne U Franssen, Roshan P Shrestha, Andrea Bräutigam, Erich Bornberg-Bauer and Andreas PM Weber
    Citation: BMC Genomics 2011 12:227
    Content type: Research article Published on:

  43. A decline in the discovery of new antibacterial drugs, coupled with a persistent rise in the occurrence of drug-resistant bacteria, has highlighted antibiotics as a diminishing resource. The future development...

    Authors: Andy Hesketh, Chris Hill, Jehan Mokhtar, Gabriela Novotna, Ngat Tran, Mervyn Bibb and Hee-Jeon Hong
    Citation: BMC Genomics 2011 12:226
    Content type: Research article Published on:

  44. Gene expression profiling studies of mastitis in ruminants have provided key but fragmented knowledge for the understanding of the disease. A systematic combination of different expression profiling studies vi...

    Authors: Sem Genini, Bouabid Badaoui, Gert Sclep, Stephen C Bishop, Dave Waddington, Marie-Hélène Pinard van der Laan, Christophe Klopp, Cédric Cabau, Hans-Martin Seyfert, Wolfram Petzl, Kirsty Jensen, Elizabeth J Glass, Astrid de Greeff, Hilde E Smith, Mari A Smits, Ingrid Olsaker…
    Citation: BMC Genomics 2011 12:225
    Content type: Research article Published on:

  45. Diapause, a state of arrested development accompanied by a marked decrease of metabolic rate, helps insects to overcome unfavorable seasons. Helicoverpa armigera (Har) undergoes pupal diapause, but the molecular ...

    Authors: Bin Bao and Wei-Hua Xu
    Citation: BMC Genomics 2011 12:224
    Content type: Research article Published on:

  46. Parasite-vector interactions are fundamental in the transmission of vector-borne diseases such as leishmaniasis. Leishmania development in the vector sand fly is confined to the digestive tract, where sand fly mi...

    Authors: Anna Dostálová, Jan Votýpka, Amanda J Favreau, Kent D Barbian, Petr Volf, Jesus G Valenzuela and Ryan C Jochim
    Citation: BMC Genomics 2011 12:223
    Content type: Research article Published on:

  47. During murine hypothalamic development, different neuroendocrine cell phenotypes are generated in overlapping periods; this suggests that cell-type specific developmental programs operate to achieve complete m...

    Authors: Magdalena Guerra-Crespo, Carlos Pérez-Monter, Sarath Chandra Janga, Santiago Castillo-Ramírez, Rosa María Gutiérrez-Rios, Patricia Joseph-Bravo, Leonor Pérez-Martínez and Jean-Louis Charli
    Citation: BMC Genomics 2011 12:222
    Content type: Research article Published on:

  48. The insect order Neuroptera encompasses more than 5,700 described species. To date, only three neuropteran mitochondrial genomes have been fully and one partly sequenced. Current knowledge on neuropteran mitoc...

    Authors: Enrico Negrisolo, Massimiliano Babbucci and Tomaso Patarnello
    Citation: BMC Genomics 2011 12:221
    Content type: Research article Published on:

  49. Root-knot nematodes are sedentary endoparasites that can infect more than 3000 plant species. Root-knot nematodes cause an estimated $100 billion annual loss worldwide. For successful establishment of the root...

    Authors: Heba MM Ibrahim, Parsa Hosseini, Nadim W Alkharouf, Ebtissam HA Hussein, Abd El Kader Y Gamal El-Din, Mohammed AM Aly and Benjamin F Matthews
    Citation: BMC Genomics 2011 12:220
    Content type: Research article Published on:

  50. Our previous studies revealed that a new disease form of streptococcal toxic shock syndrome (STSS) is associated with specific Streptococcus suis serotype 2 (SS2) strains. To achieve a better understanding of the...

    Authors: Zuowei Wu, Ming Li, Changjun Wang, Jing Li, Na Lu, Ruifen Zhang, Yongqiang Jiang, Ruifu Yang, Cuihua Liu, Hui Liao, George F Gao, Jiaqi Tang and Baoli Zhu
    Citation: BMC Genomics 2011 12:219
    Content type: Research article Published on:

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BMC Genomics

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