Skip to main content

Articles

Page 272 of 332

  1. The medicinal leech, Hirudo medicinalis, is an important model system for the study of nervous system structure, function, development, regeneration and repair. It is also a unique species in being presently appr...

    Authors: Eduardo R Macagno, Terry Gaasterland, Lee Edsall, Vineet Bafna, Marcelo B Soares, Todd Scheetz, Thomas Casavant, Corinne Da Silva, Patrick Wincker, Aurélie Tasiemski and Michel Salzet
    Citation: BMC Genomics 2010 11:407
    Content type: Research article Published on:

  2. The domestic cat has offered enormous genomic potential in the veterinary description of over 250 hereditary disease models as well as the occurrence of several deadly feline viruses (feline leukemia virus -- ...

    Authors: James C Mullikin, Nancy F Hansen, Lei Shen, Heather Ebling, William F Donahue, Wei Tao, David J Saranga, Adrianne Brand, Marc J Rubenfield, Alice C Young, Pedro Cruz, Carlos Driscoll, Victor David, Samer WK Al-Murrani, Mary F Locniskar, Mitchell S Abrahamsen…
    Citation: BMC Genomics 2010 11:406
    Content type: Database Published on:

  3. Serine proteases (SPs) and serine proteases homologs (SPHs) are a large group of proteolytic enzymes, with important roles in a variety of physiological processes, such as cell signalling, defense and developm...

    Authors: Ping Zhao, Gen-Hong Wang, Zhao-Ming Dong, Jun Duan, Ping-Zhen Xu, Ting-Cai Cheng, Zhong-Huai Xiang and Qing-You Xia
    Citation: BMC Genomics 2010 11:405
    Content type: Research article Published on:

  4. Extreme acidic environments are characterized by their high metal content and lack of nutrients (oligotrophy). Macroscopic biofilms and filaments usually grow on the water-air interface or under the stream att...

    Authors: Mercedes Moreno-Paz, Manuel J Gómez, Aida Arcas and Víctor Parro
    Citation: BMC Genomics 2010 11:404
    Content type: Research article Published on:

  6. Thousands of plants and animals possess pharmacological properties and there is an increased interest in using these materials for therapy and health maintenance. Efficacies of the application is critically de...

    Authors: Shao-Ke Lou, Ka-Lok Wong, Ming Li, Paul Pui-Hay But, Stephen Kwok-Wing Tsui and Pang-Chui Shaw
    Citation: BMC Genomics 2010 11:402
    Content type: Database Published on:

  7. About 10% of cases of male infertility are due to the presence of microdeletions within the long arm of the Y chromosome (Yq). Despite the large literature covering this critical issue, very little is known ab...

    Authors: Valentina Gatta, Florina Raicu, Alberto Ferlin, Ivana Antonucci, Anna Paola Scioletti, Andrea Garolla, Giandomenico Palka, Carlo Foresta and Liborio Stuppia
    Citation: BMC Genomics 2010 11:401
    Content type: Research article Published on:

  8. Whitefly (Bemisia tabaci) causes extensive crop damage throughout the world by feeding directly on plants and by vectoring hundreds of species of begomoviruses. Yet little is understood about its genes involved i...

    Authors: Xiao-Wei Wang, Jun-Bo Luan, Jun-Min Li, Yan-Yuan Bao, Chuan-Xi Zhang and Shu-Sheng Liu
    Citation: BMC Genomics 2010 11:400
    Content type: Research article Published on:

  9. Alternative splicing is known to increase the complexity of mammalian transcriptomes since nearly all mammalian genes express multiple pre-mRNA isoforms. However, our knowledge of the extent and function of al...

    Authors: Timothée Revil, Daniel Gaffney, Christel Dias, Jacek Majewski and Loydie A Jerome-Majewska
    Citation: BMC Genomics 2010 11:399
    Content type: Research article Published on:

  10. Digital gene expression profiling was used to characterize the assembly of genes expressed in equine skeletal muscle and to identify the subset of genes that were differentially expressed following a ten-month...

    Authors: Beatrice A McGivney, Paul A McGettigan, John A Browne, Alexander CO Evans, Rita G Fonseca, Brendan J Loftus, Amanda Lohan, David E MacHugh, Barbara A Murphy, Lisa M Katz and Emmeline W Hill
    Citation: BMC Genomics 2010 11:398
    Content type: Research article Published on:

  11. Carbonic anhydrases (CAs) are a family of enzymes that regulate pH homeostasis in various tissues. CA IX is an exceptional member of this family because in addition to the basic CA function, it has been implic...

    Authors: Heini Kallio, Mika Hilvo, Alejandra Rodriguez, Eeva-Helena Lappalainen, Anna-Maria Lappalainen and Seppo Parkkila
    Citation: BMC Genomics 2010 11:397
    Content type: Research article Published on:

  13. Genetically anchored physical maps of large eukaryotic genomes have proven useful both for their intrinsic merit and as an adjunct to genome sequencing. Cultivated tetraploid cottons, Gossypium hirsutum and G. ba...

    Authors: Lifeng Lin, Gary J Pierce, John E Bowers, James C Estill, Rosana O Compton, Lisa K Rainville, Changsoo Kim, Cornelia Lemke, Junkang Rong, Haibao Tang, Xiyin Wang, Michele Braidotti, Amy H Chen, Kristen Chicola, Kristi Collura, Ethan Epps…
    Citation: BMC Genomics 2010 11:395
    Content type: Research article Published on:

  14. Trypanosomosis is the most economically important disease constraint to livestock productivity in Africa. A number of trypanotolerant cattle breeds are found in West Africa, and identification of the genes con...

    Authors: Joseph K Nganga, Morris Soller and Fuad A Iraqi
    Citation: BMC Genomics 2010 11:394
    Content type: Research article Published on:

  15. The genus Erwinia includes plant-associated pathogenic and non-pathogenic Enterobacteria. Important pathogens such as Erwinia amylovora, the causative agent of fire blight and E. pyrifoliae causing bacterial shoo...

    Authors: Michael Kube, Alexander M Migdoll, Isabel Gehring, Katja Heitmann, Yvonne Mayer, Heiner Kuhl, Florian Knaust, Klaus Geider and Richard Reinhardt
    Citation: BMC Genomics 2010 11:393
    Content type: Research article Published on:

  16. The zebrafish intestine is a simple tapered tube that is folded into three sections. However, whether the intestine is functionally similar along its length remains unknown. Thus, a systematic structural and f...

    Authors: Zhengyuan Wang, Jianguo Du, Siew Hong Lam, Sinnakarupan Mathavan, Paul Matsudaira and Zhiyuan Gong
    Citation: BMC Genomics 2010 11:392
    Content type: Research article Published on:

  18. Understanding the genetic basis of adaptive changes has been a major goal of evolutionary biology. In complex organisms without sequenced genomes, de novo transcriptome assembly using a longer read sequencing ...

    Authors: Wiesław Babik, Michał Stuglik, Weihong Qi, Marzanna Kuenzli, Katarzyna Kuduk, Paweł Koteja and Jacek Radwan
    Citation: BMC Genomics 2010 11:390
    Content type: Research article Published on:

  19. Clostridium difficile is a Gram-positive, anaerobic, spore-forming bacterium that is responsible for C. difficile associated disease in humans and is currently the most common cause of nosocomial diarrhoea in the...

    Authors: Gemma L Marsden, Ian J Davis, Victoria J Wright, Mohammed Sebaihia, Ed J Kuijper and Nigel P Minton
    Citation: BMC Genomics 2010 11:389
    Content type: Research article Published on:

  20. Circulating CD34+ progenitor cells have the potential to differentiate into a variety of cells, including endothelial cells. Knowledge is still scarce about the transcriptional programs used by CD34+ cells fro...

    Authors: Tineke CTM van der Pouw Kraan, Stephan H Schirmer, Joost O Fledderus, Perry D Moerland, Josefien M Baggen, Thomas A Leyen, Anja M van der Laan, Jan J Piek, Niels van Royen and Anton JG Horrevoets
    Citation: BMC Genomics 2010 11:388
    Content type: Research article Published on:

  21. Emerging methods of massive sequencing that allow for rapid re-sequencing of entire genomes at comparably low cost are changing the way biological questions are addressed in many domains. Here we propose a nov...

    Authors: Julien Portela, Christoph Grunau, Céline Cosseau, Sophie Beltran, Christelle Dantec, Hugues Parrinello and Jérôme Boissier
    Citation: BMC Genomics 2010 11:387
    Content type: Methodology article Published on:

  22. Chromatin in the nucleus of all eukaryotes is organized into a system of loops and domains. These loops remain fastened at their bases to the fundamental framework of the nucleus, the matrix or the scaffold. T...

    Authors: Sushma S Padmaja, Jagannathan Lakshmanan, Ravi Gupta, Santanu Banerjee, Pennathur Gautam and Sulagna Banerjee
    Citation: BMC Genomics 2010 11:386
    Content type: Research article Published on:

  24. Cucumber, Cucumis sativus L., is an economically and nutritionally important crop of the Cucurbitaceae family and has long served as a primary model system for sex determination studies. Recently, the sequencing ...

    Authors: Shaogui Guo, Yi Zheng, Je-Gun Joung, Shiqiang Liu, Zhonghua Zhang, Oswald R Crasta, Bruno W Sobral, Yong Xu, Sanwen Huang and Zhangjun Fei
    Citation: BMC Genomics 2010 11:384
    Content type: Research article Published on:

  25. Tiling arrays have been the tool of choice for probing an organism's transcriptome without prior assumptions about the transcribed regions, but RNA-Seq is becoming a viable alternative as the costs of sequenci...

    Authors: Ashish Agarwal, David Koppstein, Joel Rozowsky, Andrea Sboner, Lukas Habegger, LaDeana W Hillier, Rajkumar Sasidharan, Valerie Reinke, Robert H Waterston and Mark Gerstein
    Citation: BMC Genomics 2010 11:383
    Content type: Research article Published on:

  26. Physical maps employing libraries of bacterial artificial chromosome (BAC) clones are essential for comparative genomics and sequencing of large and repetitive genomes such as those of the hexaploid bread whea...

    Authors: Delphine Fleury, Ming-Cheng Luo, Jan Dvorak, Luke Ramsay, Bikram S Gill, Olin D Anderson, Frank M You, Zahra Shoaei, Karin R Deal and Peter Langridge
    Citation: BMC Genomics 2010 11:382
    Content type: Research article Published on:

  27. Biological processes occur on a vast range of time scales, and many of them occur concurrently. As a result, system-wide measurements of gene expression have the potential to capture many of these processes si...

    Authors: David A Orlando, Siobhan M Brady, Thomas MA Fink, Philip N Benfey and Sebastian E Ahnert
    Citation: BMC Genomics 2010 11:381
    Content type: Methodology article Published on:

  29. The Ralstonia solanacearum species complex includes thousands of strains pathogenic to an unusually wide range of plant species. These globally dispersed and heterogeneous strains cause bacterial wilt diseases, w...

    Authors: Benoît Remenant, Bénédicte Coupat-Goutaland, Alice Guidot, Gilles Cellier, Emmanuel Wicker, Caitilyn Allen, Mark Fegan, Olivier Pruvost, Mounira Elbaz, Alexandra Calteau, Gregory Salvignol, Damien Mornico, Sophie Mangenot, Valérie Barbe, Claudine Médigue and Philippe Prior
    Citation: BMC Genomics 2010 11:379
    Content type: Research article Published on:

  30. The developmental transition between the late fetus and a newborn animal is associated with profound changes in skeletal muscle function as it adapts to the new physiological demands of locomotion and postural...

    Authors: Keren Byrne, Tony Vuocolo, Cedric Gondro, Jason D White, Noelle E Cockett, Tracy Hadfield, Christopher A Bidwell, Jolena N Waddell and Ross L Tellam
    Citation: BMC Genomics 2010 11:378
    Content type: Research article Published on:

  32. Recently, a new livestock-associated methicillin-resistant Staphylococcus aureus (MRSA) Sequence Type 398 (ST398) isolate has emerged worldwide. Although there have been reports of invasive disease in humans, MRS...

    Authors: Maarten J Schijffelen, CH Edwin Boel, Jos AG van Strijp and Ad C Fluit
    Citation: BMC Genomics 2010 11:376
    Content type: Research article Published on:

  33. Worldwide, bacterial vaginosis (BV) is the most common vaginal disorder. It is associated with risk for preterm birth and HIV infection. The etiology of the condition has been debated for nearly half a century...

    Authors: Michael D Harwich Jr, Joao M Alves, Gregory A Buck, Jerome F Strauss III, Jennifer L Patterson, Aminat T Oki, Philippe H Girerd and Kimberly K Jefferson
    Citation: BMC Genomics 2010 11:375
    Content type: Research article Published on:

  34. The size and repetitive nature of the Rhipicephalus microplus genome makes obtaining a full genome sequence fiscally and technically problematic. To selectively obtain gene-enriched regions of this tick's genome,...

    Authors: Felix D Guerrero, Paula Moolhuijzen, Daniel G Peterson, Shelby Bidwell, Elisabet Caler, Matthew Bellgard, Vishvanath M Nene and Appolinaire Djikeng
    Citation: BMC Genomics 2010 11:374
    Content type: Research article Published on:

  35. Authors: Ying Wang, Vinayak Brahmakshatriya, Huifeng Zhu, Blanca Lupiani, Sanjay M Reddy, Byung-Jun Yoon, Preethi H Gunaratne, Jong Hwan Kim, Rui Chen, Ashley L Benham, Junjun Wang and Huaijun Zhou
    Citation: BMC Genomics 2010 11:373
    Content type: Erratum Published on:

    The original article was published in BMC Genomics 2009 10:512

  37. Animal mitochondrial genomes are potential models for molecular evolution and markers for phylogenetic and population studies. Previous research has shown interesting features in hymenopteran mitochondrial gen...

    Authors: Shu-jun Wei, Min Shi, Michael J Sharkey, Cornelis van Achterberg and Xue-xin Chen
    Citation: BMC Genomics 2010 11:371
    Content type: Research article Published on:

  38. Two types of horns are evident in cattle - fixed horns attached to the skull and a variation called scurs, which refers to small loosely attached horns. Cattle lacking horns are referred to as polled. Although...

    Authors: Maxy Mariasegaram, Antonio Reverter, Wes Barris, Sigrid A Lehnert, Brian Dalrymple and Kishore Prayaga
    Citation: BMC Genomics 2010 11:370
    Content type: Research article Published on:

  39. Species of the family Vibrionaceae are ubiquitous in marine environments. Several of these species are important pathogens of humans and marine species. Evidence indicates that genetic exchange plays an important...

    Authors: Timothy G Lilburn, Jianying Gu, Hong Cai and Yufeng Wang
    Citation: BMC Genomics 2010 11:369
    Content type: Research article Published on:

  40. elicobacter pylori infection is associated with several gastro-duodenal inflammatory diseases of various levels of severity. To determine whether certain combinations of genetic markers can be used to predict the...

    Authors: Jean-Michel Thiberge, Caroline Boursaux-Eude, Philippe Lehours, Marie-Agnès Dillies, Sophie Creno, Jean-Yves Coppée, Zoé Rouy, Aurélie Lajus, Laurence Ma, Christophe Burucoa, Anne Ruskoné-Foumestraux, Anne Courillon-Mallet, Hilde De Reuse, Ivo Gomperts Boneca, Dominique Lamarque, Francis Mégraud…
    Citation: BMC Genomics 2010 11:368
    Content type: Research article Published on:

  41. The ubiquitin-conjugating enzyme HR6B is required for spermatogenesis in mouse. Loss of HR6B results in aberrant histone modification patterns on the trancriptionally silenced X and Y chromosomes (XY body) and...

    Authors: Eskeatnaf Mulugeta Achame, Evelyne Wassenaar, Jos W Hoogerbrugge, Esther Sleddens-Linkels, Marja Ooms, Zu-Wen Sun, Wilfred FJ van IJcken, J Anton Grootegoed and Willy M Baarends
    Citation: BMC Genomics 2010 11:367
    Content type: Research article Published on:

  42. Dinophysis is exceptional among dinoflagellates, possessing plastids derived from cryptophyte algae. Although Dinophysis can be maintained in pure culture for several months, the genus is mixotrophic and needs to...

    Authors: Jennifer H Wisecaver and Jeremiah D Hackett
    Citation: BMC Genomics 2010 11:366
    Content type: Research article Published on:

  43. Spinal cord injury leads to neurological dysfunctions affecting the motor, sensory as well as the autonomic systems. Increased excitability of motor neurons has been implicated in injury-induced spasticity, wh...

    Authors: Jesper Ryge, Ole Winther, Jacob Wienecke, Albin Sandelin, Ann-Charlotte Westerdahl, Hans Hultborn and Ole Kiehn
    Citation: BMC Genomics 2010 11:365
    Content type: Research article Published on:

  44. Cell functions depend on molecules organized in the cellular society. Two basic components are mRNA molecules and proteins. The interactions within and between those two components are crucial for carrying out...

    Authors: Haiyun Wang, Qi Wang, Utz J Pape, Bairong Shen, Jianhua Huang, Bin Wu and Xia Li
    Citation: BMC Genomics 2010 11:364
    Content type: Research article Published on:

  45. Ticks secrete a cement cone composed of many salivary proteins, some of which are rich in the amino acid glycine in order to attach to their hosts' skin. Glycine-rich proteins (GRPs) are a large family of hete...

    Authors: Sandra R Maruyama, Elen Anatriello, Jennifer M Anderson, José M Ribeiro, Lucinda G Brandão, Jesus G Valenzuela, Beatriz R Ferreira, Gustavo R Garcia, Matias PJ Szabó, Sonal Patel, Richard Bishop and Isabel KF de Miranda-Santos
    Citation: BMC Genomics 2010 11:363
    Content type: Research article Published on:

  46. The Antarctic clam, Laternula elliptica, is an infaunal stenothermal bivalve mollusc with a circumpolar distribution. It plays a significant role in bentho-pelagic coupling and hence has been proposed as a sentin...

    Authors: Melody S Clark, Michael AS Thorne, Florbela A Vieira, João CR Cardoso, Deborah M Power and Lloyd S Peck
    Citation: BMC Genomics 2010 11:362
    Content type: Research article Published on:

  47. Differences in gene expression may be caused by nearby DNA polymorphisms (cis regulation) or by interactions of gene control regions with polymorphic transcription factors (trans regulation). Trans acting loci ar...

    Authors: Harry A Noyes, Morris Agaba, Susan Anderson, Alan L Archibald, Andy Brass, John Gibson, Laurence Hall, Helen Hulme, Sung Jong Oh and Stephen Kemp
    Citation: BMC Genomics 2010 11:361
    Content type: Research article Published on:

  48. Increases during aging in extracellular levels of glutamate (Glu), the major excitatory neurotransmitter in the brain, may be linked to chronic neurodegenerative diseases. Little is known about the molecular r...

    Authors: Xinkun Wang, Xiaodong Bao, Ranu Pal, Abdulbaki Agbas and Elias K Michaelis
    Citation: BMC Genomics 2010 11:360
    Content type: Research article Published on:

  49. Glucocorticoids (GCs) control expression of a large number of genes via binding to the GC receptor (GR). Transcription may be regulated either by binding of the GR dimer to DNA regulatory elements or by protei...

    Authors: Raoul Frijters, Wilco Fleuren, Erik JM Toonen, Jan P Tuckermann, Holger M Reichardt, Hans van der Maaden, Andrea van Elsas, Marie-Jose van Lierop, Wim Dokter, Jacob de Vlieg and Wynand Alkema
    Citation: BMC Genomics 2010 11:359
    Content type: Research article Published on:

  50. The human genome displays extensive copy-number variation (CNV). Recent discoveries have shown that large segments of DNA, ranging in size from hundreds to thousands of nucleotides, are either deleted or dupli...

    Authors: Krishna R Kalari, Scott J Hebbring, High Seng Chai, Liang Li, Jean-Pierre A Kocher, Liewei Wang and Richard M Weinshilboum
    Citation: BMC Genomics 2010 11:357
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Annual Journal Metrics

  • 2022 Citation Impact
    4.4 - 2-year Impact Factor
    4.7 - 5-year Impact Factor
    1.189 - SNIP (Source Normalized Impact per Paper)
    1.107 - SJR (SCImago Journal Rank)

    2023 Speed
    23 days submission to first editorial decision for all manuscripts (Median)
    137 days submission to accept (Median)

    2023 Usage
    7,167,242 downloads
    4,454 Altmetric mentions

Follow

Sign up for article alerts and news from this journal

BMC Genomics

ISSN: 1471-2164

Contact us