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  1. The v-erbA oncogene, carried by the Avian Erythroblastosis Virus, derives from the c-erbAα proto-oncogene that encodes the nuclear receptor for triiodothyronine (T3R). v-ErbA transforms erythroid progenitors in v...

    Authors: Corinne Bresson, Celine Keime, Claudine Faure, Yann Letrillard, Maud Barbado, Sandra Sanfilippo, Najate Benhra, Olivier Gandrillon and Sandrine Gonin-Giraud
    Citation: BMC Genomics 2007 8:390
  2. Fetal alcohol syndrome (FAS) is a serious global health problem and is observed at high frequencies in certain South African communities. Although in utero alcohol exposure is the primary trigger, there is eviden...

    Authors: Zané Lombard, Nicki Tiffin, Oliver Hofmann, Vladimir B Bajic, Winston Hide and Michèle Ramsay
    Citation: BMC Genomics 2007 8:389
  3. Despite the improvements of tools for automated annotation of genome sequences, manual curation at the structural and functional level can provide an increased level of refinement to genome annotation. The Ins...

    Authors: Françoise Thibaud-Nissen, Matthew Campbell, John P Hamilton, Wei Zhu and C Robin Buell
    Citation: BMC Genomics 2007 8:388
  4. Mitochondrial genomes are widely utilized for phylogenetic and population genetic analyses among animals. In addition to sequence data the mitochondrial gene order and RNA secondary structure data are used in ...

    Authors: Kathrin Fahrein, Giovanni Talarico, Anke Braband and Lars Podsiadlowski
    Citation: BMC Genomics 2007 8:386
  5. The t(12;21)(p13;q22) translocation is found in 20 to 25% of cases of childhood B-lineage acute lymphoblastic leukemia (B-ALL). This rearrangement results in the fusion of ETV6 (TEL) and RUNX1 (AML1) genes and de...

    Authors: Virginie Gandemer, Anne-Gaëlle Rio, Marie de Tayrac, Vonnick Sibut, Stéphanie Mottier, Béatrice Ly Sunnaram, Catherine Henry, Annabelle Monnier, Christian Berthou, Edouard Le Gall, André Le Treut, Claudine Schmitt, Jean-Yves Le Gall, Jean Mosser and Marie-Dominique Galibert
    Citation: BMC Genomics 2007 8:385
  6. The differentiation of hematopoietic stem cells into platelet-forming megakaryocytes is of fundamental importance to hemostasis. Constitutive apoptosis is an integral, yet poorly understood, facet of megakaryo...

    Authors: Chi Chen, Peter G Fuhrken, Li Ting Huang, Pani Apostolidis, Min Wang, Carlos J Paredes, William M Miller and Eleftherios T Papoutsakis
    Citation: BMC Genomics 2007 8:384
  7. Understanding how mesenchymal cells arise from epithelial cells could have a strong impact in unveiling mechanisms of epithelial cell plasticity underlying kidney regeneration and repair.

    Authors: Stefano Campanaro, Simone Picelli, Rossella Torregrossa, Laura Colluto, Monica Ceol, Dorella Del Prete, Angela D'Angelo, Giorgio Valle and Franca Anglani
    Citation: BMC Genomics 2007 8:383
  8. High-resolution microarray-based comparative genomic hybridization (CGH) techniques have successfully been applied to study copy number imbalances in a number of settings such as the analysis of cancer genomes...

    Authors: Johan Staaf, Göran Jönsson, Markus Ringnér and Johan Vallon-Christersson
    Citation: BMC Genomics 2007 8:382
  9. Oil palm is the second largest source of edible oil which contributes to approximately 20% of the world's production of oils and fats. In order to understand the molecular biology involved in in vitro propagation...

    Authors: Chai-Ling Ho, Yen-Yen Kwan, Mei-Chooi Choi, Sue-Sean Tee, Wai-Har Ng, Kok-Ang Lim, Yang-Ping Lee, Siew-Eng Ooi, Weng-Wah Lee, Jin-Ming Tee, Siang-Hee Tan, Harikrishna Kulaveerasingam, Sharifah Shahrul Rabiah Syed Alwee and Meilina Ong Abdullah
    Citation: BMC Genomics 2007 8:381
  10. Recently, we demonstrated that human mesenchymal stem cells (hMSC) stimulated with dexamethazone undergo gene focusing during osteogenic differentiation (Stem Cells Dev 14(6): 1608–20, 2005). Here, we examine the...

    Authors: Kristin P Bennett, Charles Bergeron, Evrim Acar, Robert F Klees, Scott L Vandenberg, Bülent Yener and George E Plopper
    Citation: BMC Genomics 2007 8:380
  11. Hereditary hemochromatosis (HH) encompasses genetic disorders of iron overload characterized by deficient expression or function of the iron-regulatory hormone hepcidin. Mutations in 5 genes have been linked t...

    Authors: Alejandra Rodriguez, Mika Hilvo, Leena Kytömäki, Robert E Fleming, Robert S Britton, Bruce R Bacon and Seppo Parkkila
    Citation: BMC Genomics 2007 8:379
  12. A substantial fraction of non-coding DNA sequences of multicellular eukaryotes is under selective constraint. In particular, ~5% of the human genome consists of conserved non-coding sequences (CNSs). CNSs diff...

    Authors: Simon Minovitsky, Philip Stegmaier, Alexander Kel, Alexey S Kondrashov and Inna Dubchak
    Citation: BMC Genomics 2007 8:378
  13. The measurement of gene expression using microarray technology is a complicated process in which a large number of factors can be varied. Due to the lack of standard calibration samples such as are used in tra...

    Authors: Torunn Bruland, Endre Anderssen, Berit Doseth, Hallgeir Bergum, Vidar Beisvag and Astrid Lægreid
    Citation: BMC Genomics 2007 8:377
  14. To better understand the molecular programs of normal and abnormal genital development, clear-cut definition of androgen-dependent gene expression patterns, without the influence of genotype (46, XX vs. 46, XY...

    Authors: Paul-Martin Holterhus, Uta Deppe, Ralf Werner, Annette Richter-Unruh, Jan-Hendrik Bebermeier, Lutz Wünsch, Susanne Krege, Hans-Udo Schweikert, Janos Demeter, Felix Riepe, Olaf Hiort and James D Brooks
    Citation: BMC Genomics 2007 8:376
  15. Non-coding RNAs (ncRNA) are regulators of gene expression in all domains of life. They control growth and differentiation, virulence, motility and various stress responses. The identification of ncRNAs can be ...

    Authors: Björn Voß, Gregor Gierga, Ilka M Axmann and Wolfgang R Hess
    Citation: BMC Genomics 2007 8:375
  16. High-density oligonucleotide arrays are widely used for analysis of genome-wide expression and genetic variation. Affymetrix GeneChips – common high-density oligonucleotide arrays – contain perfect match (PM) ...

    Authors: Shingo Suzuki, Naoaki Ono, Chikara Furusawa, Akiko Kashiwagi and Tetsuya Yomo
    Citation: BMC Genomics 2007 8:373
  17. The different physiological repertoire of CA3 and CA1 neurons in the hippocampus, as well as their differing behaviour after noxious stimuli are ultimately based upon differences in the expressed genome. We ha...

    Authors: Dieter Newrzella, Payam S Pahlavan, Carola Krüger, Christine Boehm, Oliver Sorgenfrei, Helmut Schröck, Gisela Eisenhardt, Nadine Bischoff, Gerhard Vogt, Oliver Wafzig, Moritz Rossner, Martin H Maurer, Holger Hiemisch, Alfred Bach, Wolfgang Kuschinsky and Armin Schneider
    Citation: BMC Genomics 2007 8:370
  18. The southern cattle tick, Rhipicephalus (Boophilus) microplus, is an economically important parasite of cattle and can transmit several pathogenic microorganisms to its cattle host during the feeding process. Und...

    Authors: Minghua Wang, Felix D Guerrero, Geo Pertea and Vishvanath M Nene
    Citation: BMC Genomics 2007 8:368
  19. The mitochondria are involved in many basic functions in cells of vertebrates, and can be considered the power generator of the cell. Though the mitochondria have been extensively studied there appear to be on...

    Authors: Karsten Scheibye-Alsing, Susanna Cirera, Michael J Gilchrist, Merete Fredholm and Jan Gorodkin
    Citation: BMC Genomics 2007 8:367
  20. Expression profiling of embryonic stem (ES) cell differentiation in the presence of serum has been performed previously. It remains unclear if transcriptional activation is dependent on complex growth factor m...

    Authors: Stephen J Bruce, Brooke B Gardiner, Les J Burke, M Milena Gongora, Sean M Grimmond and Andrew C Perkins
    Citation: BMC Genomics 2007 8:365
  21. In order to devise efficient treatments for complex, multi-factorial diseases, it is important to identify the genes which regulate multiple cellular processes. Exposure to elevated levels of free fatty acids ...

    Authors: Shireesh Srivastava, Zheng Li, Xuerui Yang, Matthew Yedwabnick, Stephen Shaw and Christina Chan
    Citation: BMC Genomics 2007 8:364
  22. Osteoblast differentiation requires the coordinated stepwise expression of multiple genes. Histone deacetylase inhibitors (HDIs) accelerate the osteoblast differentiation process by blocking the activity of hi...

    Authors: Tania M Schroeder, Aswathy K Nair, Rodney Staggs, Anne-Francoise Lamblin and Jennifer J Westendorf
    Citation: BMC Genomics 2007 8:362
  23. The gut is a major energy consumer, but a comprehensive overview of the adaptive response to fasting is lacking. Gene-expression profiling, pathway analysis, and immunohistochemistry were therefore carried out...

    Authors: Milka Sokolović, Diederik Wehkamp, Aleksandar Sokolović, Jacqueline Vermeulen, Lisa A Gilhuijs-Pederson, Rachel IM van Haaften, Yuri Nikolsky, Chris TA Evelo, Antoine HC van Kampen, Theodorus BM Hakvoort and Wouter H Lamers
    Citation: BMC Genomics 2007 8:361
  24. A systematic survey of loci carrying retrotransposons in the genome of the rice blast fungus Magnaporthe grisea allowed the identification of novel non-canonical retropseudogenes. These elements are chimeric retr...

    Authors: Elena Gogvadze, Crystel Barbisan, Marc-Henri Lebrun and Anton Buzdin
    Citation: BMC Genomics 2007 8:360
  25. Campylobacter jejuni infection represents the most frequent antecedent infection triggering the onset of the neuropathic disorders Guillain-Barré syndrome (GBS) and Miller Fisher syndrome (MFS). Although sialylat...

    Authors: Eduardo N Taboada, Alex van Belkum, Nobuhiro Yuki, Rey R Acedillo, Peggy CR Godschalk, Michiaki Koga, Hubert P Endtz, Michel Gilbert and John HE Nash
    Citation: BMC Genomics 2007 8:359
  26. Our understanding of the importance of transcriptional regulation for biological function is continuously improving. We still know, however, comparatively little about how environmentally induced stress affect...

    Authors: Karin S Kassahn, Ross H Crozier, Alister C Ward, Glenn Stone and M Julian Caley
    Citation: BMC Genomics 2007 8:358
  27. Fish gonadal sex differentiation is affected by sex steroids treatments providing an efficient strategy to control the sexual phenotype of fish for aquaculture purposes. However, the biological effects of such...

    Authors: Daniel Baron, Jérôme Montfort, Rémi Houlgatte, Alexis Fostier and Yann Guiguen
    Citation: BMC Genomics 2007 8:357
  28. The emergence of high throughput genome sequencing facilities and powerful high performance bioinformatic tools has highlighted hitherto unexpected wide occurrence of globins in the three kingdoms of life. In sil...

    Authors: David Hoogewijs, Eva Geuens, Sylvia Dewilde, Andy Vierstraete, Luc Moens, Serge Vinogradov and Jacques R Vanfleteren
    Citation: BMC Genomics 2007 8:356
  29. Chlamydophila pneumoniae is an obligate intracellular bacterium that replicates in a biphasic life cycle within eukaryotic host cells. Four published genomes revealed an identity of > 99 %. This remarkable findin...

    Authors: Thomas Rattei, Stephan Ott, Michaela Gutacker, Jan Rupp, Matthias Maass, Stefan Schreiber, Werner Solbach, Thierry Wirth and Jens Gieffers
    Citation: BMC Genomics 2007 8:355
  30. Freshwater fish absorb Ca2+ predominantly from ambient water, and more than 97% of Ca2+ uptake is achieved by active transport through gill mitochondrion-rich (MR) cells. In the current model for Ca2+ uptake in g...

    Authors: Bo-Kai Liao, Ang-Ni Deng, Shyh-Chi Chen, Ming-Yi Chou and Pung-Pung Hwang
    Citation: BMC Genomics 2007 8:354
  31. Adjacent gene pairs in the yeast genome have a tendency to express concurrently. Sharing of regulatory elements within the intergenic region of those adjacent gene pairs was often considered the major mechanis...

    Authors: Huai-Kuang Tsai, Cindy PC Su, Mei-Yeh J Lu, Ching-Hua Shih and Daryi Wang
    Citation: BMC Genomics 2007 8:352
  32. Staphylococcus aureus is an important human pathogen, causing a wide variety of diseases ranging from superficial skin infections to severe life threatening infections. S. aureus is one of the leading causes of n...

    Authors: Vijayaraj Nagarajan and Mohamed O Elasri
    Citation: BMC Genomics 2007 8:351
  33. Cadmium is a persistent pollutant that threatens most biological organisms, including cyanobacteria that support a large part of the biosphere. Using a multifaceted approach, we have investigated the global re...

    Authors: Laetitia Houot, Martin Floutier, Benoit Marteyn, Magali Michaut, Antoine Picciocchi, Pierre Legrain, Jean-Christophe Aude, Corinne Cassier-Chauvat and Franck Chauvat
    Citation: BMC Genomics 2007 8:350
  34. The aim of this study was to analyze the genomic diversity of several Tropheryma whipplei strains by microarray-based comparative genomic hybridization. Fifteen clinical isolates originating from biopsy samples r...

    Authors: My-Van La, Nicolas Crapoulet, Pascal Barbry, Didier Raoult and Patricia Renesto
    Citation: BMC Genomics 2007 8:349
  35. Chromosomal instability (CIN) is the most prevalent type of genomic instability in gastric tumours, but its role in malignant transformation of the gastric mucosa is still obscure. In the present study, we set...

    Authors: Tineke E Buffart, Beatriz Carvalho, Thomas Mons, Rui M Reis, Cátia Moutinho, Paula Silva, Nicole CT van Grieken, Michael Vieth, Manfred Stolte, Cornelis JH van de Velde, Evelin Schrock, Anja Matthaei, Bauke Ylstra, Fátima Carneiro and Gerrit A Meijer
    Citation: BMC Genomics 2007 8:345
  36. Affymetrix GeneChip arrays are widely used for transcriptomic studies in a diverse range of species. Each gene is represented on a GeneChip array by a probe-set, consisting of up to 16 probe-pairs. Signal inte...

    Authors: Neil S Graham, Martin R Broadley, John P Hammond, Philip J White and Sean T May
    Citation: BMC Genomics 2007 8:344
  37. The phylogenetic position of pycnogonids is a long-standing and controversial issue in arthropod phylogeny. This controversy has recently been rekindled by differences in the conclusions based on neuroanatomic...

    Authors: Shin-Ju Park, Yong-Seok Lee and Ui Wook Hwang
    Citation: BMC Genomics 2007 8:343
  38. The AZFc region of the human Y chromosome is a highly recombinogenic locus containing multi-copy male fertility genes located in repeated DNA blocks (amplicons). These AZFc gene families exhibit slight sequenc...

    Authors: Paulo Navarro-Costa, Luísa Pereira, Cíntia Alves, Leonor Gusmão, Carmen Proença, Pedro Marques-Vidal, Tiago Rocha, Sónia C Correia, Sónia Jorge, António Neves, Ana P Soares, Joaquim Nunes, Carlos Calhaz-Jorge, António Amorim, Carlos E Plancha and João Gonçalves
    Citation: BMC Genomics 2007 8:342

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