Skip to main content

Articles

Page 290 of 332

  1. The Plasmodium falciparum genome (3D7 strain) published in 2002, revealed ~5,400 genes, mostly based on in silico predictions. Experimental data is therefore required for structural and functional assessments of

    Authors: Isabelle Florent, Betina M Porcel, Elodie Guillaume, Corinne Da Silva, François Artiguenave, Eric Maréchal, Laurent Bréhélin, Olivier Gascuel, Sébastien Charneau, Patrick Wincker and Philippe Grellier
    Citation: BMC Genomics 2009 10:235
    Content type: Research article Published on:

  2. Flesh flies in the genus Sarcophaga are important models for investigating endocrinology, diapause, cold hardiness, reproduction, and immunity. Despite the prominence of Sarcophaga flesh flies as models for insec...

    Authors: Daniel A Hahn, Gregory J Ragland, D DeWayne Shoemaker and David L Denlinger
    Citation: BMC Genomics 2009 10:234
    Content type: Research article Published on:

  3. The Tec-family kinase Itk plays an important role during T-cell activation and function, and controls also conventional versus innate-like T-cell development. We have characterized the transcriptome of Itk-def...

    Authors: K Emelie M Blomberg, Nicole Boucheron, Jessica M Lindvall, Liang Yu, Julia Raberger, Anna Berglöf, Wilfried Ellmeier and CI Edvard Smith
    Citation: BMC Genomics 2009 10:233
    Content type: Research article Published on:

  4. The protozoan pathogens Leishmania major, Trypanosoma brucei and Trypanosoma cruzi (the Tritryps) are parasites that produce devastating human diseases. These organisms show very unusual mechanisms of gene expres...

    Authors: Norma E Padilla-Mejía, Luis E Florencio-Martínez, Elisa E Figueroa-Angulo, Rebeca G Manning-Cela, Rosaura Hernández-Rivas, Peter J Myler and Santiago Martínez-Calvillo
    Citation: BMC Genomics 2009 10:232
    Content type: Research article Published on:

  5. Stat5 is a latent transcription factor that regulates essential growth and survival functions in normal cells. Constitutive activity of Stat5 and the involvement of its C-terminally truncated variant have been...

    Authors: Tali Eilon and Itamar Barash
    Citation: BMC Genomics 2009 10:231
    Content type: Research article Published on:

  6. Correction to Dolan J, Walshe K, Alsbury S, Hokamp K, O'Keeffe S, Okafuji T, Miller SF, Tear G, Mitchell KJ: The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary...

    Authors: Jackie Dolan, Karen Walshe, Samantha Alsbury, Karsten Hokamp, Sean O'Keeffe, Tatsuya Okafuji, Suzanne FC Miller, Guy Tear and Kevin J Mitchell
    Citation: BMC Genomics 2009 10:230
    Content type: Erratum Published on:

    The original article was published in BMC Genomics 2007 8:320

  7. Cyanobacteria of the genera Synechococcus and Prochlorococcus play a key role in marine photosynthesis, which contributes to the global carbon cycle and to the world oxygen supply. Recently, genes encoding the ph...

    Authors: Shani Tzahor, Dikla Man-Aharonovich, Benjamin C Kirkup, Tali Yogev, Ilana Berman-Frank, Martin F Polz, Oded Béjà and Yael Mandel-Gutfreund
    Citation: BMC Genomics 2009 10:229
    Content type: Research article Published on:

  8. Neuropeptides are cell to cell signalling molecules that regulate many critical biological processes including development, growth and reproduction. These peptides result from the complex processing of prohorm...

    Authors: Bruce R Southey, Sandra L Rodriguez-Zas and Jonathan V Sweedler
    Citation: BMC Genomics 2009 10:228
    Content type: Research article Published on:

  12. Soft-shelled turtle iridovirus (STIV) is the causative agent of severe systemic diseases in cultured soft-shelled turtles (Trionyx sinensis). To our knowledge, the only molecular information available on STIV mai...

    Authors: Youhua Huang, Xiaohong Huang, Hong Liu, Jie Gong, Zhengliang Ouyang, Huachun Cui, Jianhao Cao, Yingtao Zhao, Xiujie Wang, Yulin Jiang and Qiwei Qin
    Citation: BMC Genomics 2009 10:224
    Content type: Research article Published on:

  13. DNA methylation is a widely studied epigenetic mechanism known to correlate with gene repression and genomic stability. Development of sensitive methods for global detection of DNA methylation events is of par...

    Authors: Jian Li, Fei Gao, Ning Li, Shengting Li, Guangliang Yin, Geng Tian, Shangang Jia, Kai Wang, Xiuqing Zhang, Huanming Yang, Anders Lade Nielsen and Lars Bolund
    Citation: BMC Genomics 2009 10:223
    Content type: Research article Published on:

  14. Hydrothermal vents and cold seeps represent oases of life in the deep-sea environment, but are also characterized by challenging physical and chemical conditions. The effect of temperature fluctuations on vent...

    Authors: Isabelle Boutet, Didier Jollivet, Bruce Shillito, Dario Moraga and Arnaud Tanguy
    Citation: BMC Genomics 2009 10:222
    Content type: Research article Published on:

  15. High-throughput cDNA synthesis and sequencing of poly(A)-enriched RNA is rapidly emerging as a technology competing to replace microarrays as a quantitative platform for measuring gene expression.

    Authors: Joshua S Bloom, Zia Khan, Leonid Kruglyak, Mona Singh and Amy A Caudy
    Citation: BMC Genomics 2009 10:221
    Content type: Research article Published on:

  17. New methods are needed for genomic-scale analysis of emerging model organisms that exemplify important biological questions but lack fully sequenced genomes. For example, there is an urgent need to understand ...

    Authors: Eli Meyer, Galina V Aglyamova, Shi Wang, Jade Buchanan-Carter, David Abrego, John K Colbourne, Bette L Willis and Mikhail V Matz
    Citation: BMC Genomics 2009 10:219
    Content type: Research article Published on:

  19. Serine proteinase inhibitors (Serpins) are a large superfamily of structurally related, but functionally diverse proteins that control essential proteolytic pathways in most branches of life. Given their impor...

    Authors: Albert Mulenga, Rabuesak Khumthong and Katelyn C Chalaire
    Citation: BMC Genomics 2009 10:217
    Content type: Research article Published on:

  20. Over the last decade, several studies have identified quantitative trait loci (QTL) affecting variation of immune related traits in mammals. Recent studies in humans and mice suggest that part of this variatio...

    Authors: Oliver C Jann, Annemarie King, Nestor Lopez Corrales, Susan I Anderson, Kirsty Jensen, Tahar Ait-ali, Haizhou Tang, Chunhua Wu, Noelle E Cockett, Alan L Archibald and Elizabeth J Glass
    Citation: BMC Genomics 2009 10:216
    Content type: Research article Published on:

  21. Wood is the end product of secondary vascular system development, which begins from the cambium. The wood formation process includes four major stages: cell expansion, secondary wall biosynthesis, lignificatio...

    Authors: Minjie Wang, Xiaoli Qi, Shutang Zhao, Shougong Zhang and Meng-Zhu Lu
    Citation: BMC Genomics 2009 10:215
    Content type: Research article Published on:

  22. MicroRNAs (miRNAs) are a large group of RNAs that play important roles in regulating gene expression and protein translation. Several studies have indicated that some miRNAs are specifically expressed in human...

    Authors: You-Jia Hua, Zhong-Yi Tang, Kang Tu, Li Zhu, Yi-Xue Li, Lu Xie and Hua-Sheng Xiao
    Citation: BMC Genomics 2009 10:214
    Content type: Research article Published on:

  23. Germ cells must progress through elaborate developmental stages from an undifferentiated germ cell to a fully differentiated gamete. Some of these stages include exiting mitosis and entering meiosis, progressi...

    Authors: Xin Wang, Yongjun Zhao, Kim Wong, Peter Ehlers, Yuji Kohara, Steven J Jones, Marco A Marra, Robert A Holt, Donald G Moerman and Dave Hansen
    Citation: BMC Genomics 2009 10:213
    Content type: Research article Published on:

  24. Water deficit has significant effects on grape berry composition resulting in improved wine quality by the enhancement of color, flavors, or aromas. While some pathways or enzymes affected by water deficit hav...

    Authors: Laurent G Deluc, David R Quilici, Alain Decendit, Jérôme Grimplet, Matthew D Wheatley, Karen A Schlauch, Jean-Michel Mérillon, John C Cushman and Grant R Cramer
    Citation: BMC Genomics 2009 10:212
    Content type: Research article Published on:

  25. Whole genome radiation hybrid (WG-RH) maps serve as "scaffolds" to significantly improve the orientation of small bacterial artificial chromosome (BAC) contigs, order genes within the contigs and assist assemb...

    Authors: Jian-Gang Ma, Hiroshi Yasue, Katie E Eyer, Hideki Hiraiwa, Takeshi Shimogiri, Stacey N Meyers, Jonathan E Beever, Lawrence B Schook, Craig W Beattie and Wan-Sheng Liu
    Citation: BMC Genomics 2009 10:211
    Content type: Research article Published on:

  26. The availability of whole-genome sequences allows for the identification of the entire set of protein coding genes as well as their regulatory regions. This can be accomplished using multiple complementary met...

    Authors: Alan L Kwan, Linya Li, David C Kulp, Susan K Dutcher and Gary D Stormo
    Citation: BMC Genomics 2009 10:210
    Content type: Research article Published on:

  29. African animal trypanosomiasis (AAT) caused by tsetse fly-transmitted protozoa of the genus Trypanosoma is a major constraint on livestock and agricultural production in Africa and is among the top ten global cat...

    Authors: Grace M O'Gorman, Stephen DE Park, Emmeline W Hill, Kieran G Meade, Paul M Coussens, Morris Agaba, Jan Naessens, Stephen J Kemp and David E MacHugh
    Citation: BMC Genomics 2009 10:207
    Content type: Research article Published on:

  30. Insect ovarioles are classified into two categories: panoistic and meroistic, the later having apparently evolved from an ancestral panoistic type. Molecular data on oogenesis is practically restricted to mero...

    Authors: Paula Irles, Xavier Bellés and M Dolors Piulachs
    Citation: BMC Genomics 2009 10:206
    Content type: Research article Published on:

  31. The entomopathogenic nematode Heterorhabditis bacteriophora and its symbiotic bacterium, Photorhabdus luminescens, are important biological control agents of insect pests. This nematode-bacterium-insect associati...

    Authors: Xiaodong Bai, Byron J Adams, Todd A Ciche, Sandra Clifton, Randy Gaugler, Saskia A Hogenhout, John Spieth, Paul W Sternberg, Richard K Wilson and Parwinder S Grewal
    Citation: BMC Genomics 2009 10:205
    Content type: Research article Published on:

  32. MicroRNAs (miRNAs), short ~21-nucleotide RNA molecules, play an important role in post-transcriptional regulation of gene expression. The number of known miRNA hairpins registered in the miRBase database is ra...

    Authors: Ate van der Burgt, Mark WJE Fiers, Jan-Peter Nap and Roeland CHJ van Ham
    Citation: BMC Genomics 2009 10:204
    Content type: Research article Published on:

  33. Next-generation sequencing technologies have been applied most often to model organisms or species closely related to a model. However, these methods have the potential to be valuable in many wild organisms, i...

    Authors: Matthew C Hale, Cory R McCormick, James R Jackson and J Andrew DeWoody
    Citation: BMC Genomics 2009 10:203
    Content type: Research article Published on:

  34. The wide use of organophosphorus (OP) pesticides makes them an important public health concern. Persistent effects of exposure and the mechanism of neuronal degeneration are continuing issues in OP toxicology....

    Authors: John A Lewis, Maria Szilagyi, Elizabeth Gehman, William E Dennis and David A Jackson
    Citation: BMC Genomics 2009 10:202
    Content type: Research article Published on:

  35. We have reported that doxycycline-induced over-expression of wild type prion protein (PrP) in skeletal muscles of Tg(HQK) mice is sufficient to cause a primary myopathy with no signs of peripheral neuropathy. ...

    Authors: Jingjing Liang, Debra Parchaliuk, Sarah Medina, Garrett Sorensen, Laura Landry, Shenghai Huang, Meiling Wang, Qingzhong Kong and Stephanie A Booth
    Citation: BMC Genomics 2009 10:201
    Content type: Research article Published on:

  36. In Arabidopsis thaliana (L.) Heynh and Oryza sativa L., a large number of genes encode proteins of unknown functions, whose characterization still remains one of the major challenges. With an aim to characterize ...

    Authors: Hemant R Kushwaha, Anil K Singh, Sudhir K Sopory, Sneh L Singla-Pareek and Ashwani Pareek
    Citation: BMC Genomics 2009 10:200
    Content type: Research article Published on:

  37. Interstitial cystitis (IC), a chronic bladder disease with an increasing incidence, is diagnosed using subjective symptoms in combination with cystoscopic and histological evidence. By cystoscopic examination,...

    Authors: Marianne Gamper, Volker Viereck, Verena Geissbühler, Jakob Eberhard, Jochen Binder, Carlo Moll, Hubert Rehrauer and René Moser
    Citation: BMC Genomics 2009 10:199
    Content type: Research article Published on:

  38. The increasing number of completely sequenced bacterial genomes allows comparing their architecture and genetic makeup. Such new information highlights the crucial role of lateral genetic exchanges in bacteria...

    Authors: Alexandre Panchaud, Lionel Guy, François Collyn, Marisa Haenni, Masanobu Nakata, Andreas Podbielski, Philippe Moreillon and Claude-Alain H Roten
    Citation: BMC Genomics 2009 10:198
    Content type: Research article Published on:

  39. Functional profiling methods have been extensively used in the context of high-throughput experiments and, in particular, in microarray data analysis. Such methods use available biological information to defin...

    Authors: David Montaner, Pablo Minguez, Fátima Al-Shahrour and Joaquín Dopazo
    Citation: BMC Genomics 2009 10:197
    Content type: Research article Published on:

  40. Myostatin (MSTN), a member of the TGF-β superfamily, has been identified as a negative regulator of skeletal muscle mass. Inactivating mutations in the MSTN gene are responsible for the development of a hyperm...

    Authors: Ilham Chelh, Bruno Meunier, Brigitte Picard, Mark James Reecy, Catherine Chevalier, Jean-François Hocquette and Isabelle Cassar-Malek
    Citation: BMC Genomics 2009 10:196
    Content type: Research article Published on:

  41. MicroRNAs (miRNAs) are a new class of small RNAs of approximately 22 nucleotides in length that control eukaryotic gene expression by fine tuning mRNA translation. They regulate a wide variety of biological pr...

    Authors: Ana R Soares, Patrícia M Pereira, Bruno Santos, Conceição Egas, Ana C Gomes, Joel Arrais, José L Oliveira, Gabriela R Moura and Manuel AS Santos
    Citation: BMC Genomics 2009 10:195
    Content type: Research article Published on:

  42. The draft genome sequence of cattle (Bos taurus) has now been analyzed by the Bovine Genome Sequencing and Analysis Consortium and the Bovine HapMap Consortium, which together represent an extensive collaboration...

    Authors: Ross L Tellam, Danielle G Lemay, Curtis P Van Tassell, Harris A Lewin, Kim C Worley and Christine G Elsik
    Citation: BMC Genomics 2009 10:193
    Content type: Commentary Published on:

  43. Successful reprogramming of a somatic genome to produce a healthy clone by somatic cells nuclear transfer (SCNT) is a rare event and the mechanisms involved in this process are poorly defined. When serial or s...

    Authors: Nelida Rodriguez-Osorio, Zhongde Wang, Poothappillai Kasinathan, Grier P Page, James M Robl and Erdogan Memili
    Citation: BMC Genomics 2009 10:190
    Content type: Research article Published on:

  44. Bidirectional promoters are shared regulatory regions that influence the expression of two oppositely oriented genes. This type of regulatory architecture is found more frequently than expected by chance in th...

    Authors: Helen Piontkivska, Mary Q Yang, Denis M Larkin, Harris A Lewin, James Reecy and Laura Elnitski
    Citation: BMC Genomics 2009 10:189
    Content type: Research article Published on:

  45. Linkage analyses strongly suggest a number of QTL for production, health and conformation traits in the middle part of bovine chromosome 6 (BTA6). The identification of the molecular background underlying the ...

    Authors: Rosemarie Weikard, Tom Goldammer, Annett Eberlein and Christa Kuehn
    Citation: BMC Genomics 2009 10:186
    Content type: Research article Published on:

  47. The cattle MHC is termed the bovine leukocyte antigen (BoLA) and, along with the MHCs of other ruminants, is unique in its genomic organization. Consequently, correct and reliable gene maps and sequence inform...

    Authors: Candice L Brinkmeyer-Langford, Christopher P Childers, Krista L Fritz, Ashley L Gustafson-Seabury, Marian Cothran, Terje Raudsepp, James E Womack and Loren C Skow
    Citation: BMC Genomics 2009 10:182
    Content type: Research article Published on:

  48. We present here the assembly of the bovine genome. The assembly method combines the BAC plus WGS local assembly used for the rat and sea urchin with the whole genome shotgun (WGS) only assembly used for many o...

    Authors: Yue Liu, Xiang Qin, Xing-Zhi Henry Song, Huaiyang Jiang, Yufeng Shen, K James Durbin, Sigbjørn Lien, Matthew Peter Kent, Marte Sodeland, Yanru Ren, Lan Zhang, Erica Sodergren, Paul Havlak, Kim C Worley, George M Weinstock and Richard A Gibbs
    Citation: BMC Genomics 2009 10:180
    Content type: Research article Published on:

  49. The goal of genome wide analyses of polymorphisms is to achieve a better understanding of the link between genotype and phenotype. Part of that goal is to understand the selective forces that have operated on ...

    Authors: William Barendse, Blair E Harrison, Rowan J Bunch, Merle B Thomas and Lex B Turner
    Citation: BMC Genomics 2009 10:178
    Content type: Research article Published on:

  50. Fertility is one of the most critical factors controlling biological and financial performance of animal production systems and genetic improvement of lines. The objective of this study was to identify molecul...

    Authors: Jean M Feugang, Abdullah Kaya, Grier P Page, Lang Chen, Tapan Mehta, Kashif Hirani, Lynne Nazareth, Einko Topper, Richard Gibbs and Erdogan Memili
    Citation: BMC Genomics 2009 10:176
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Annual Journal Metrics

  • 2022 Citation Impact
    4.4 - 2-year Impact Factor
    4.7 - 5-year Impact Factor
    1.189 - SNIP (Source Normalized Impact per Paper)
    1.107 - SJR (SCImago Journal Rank)

    2023 Speed
    23 days submission to first editorial decision for all manuscripts (Median)
    137 days submission to accept (Median)

    2023 Usage
    7,167,242 downloads
    4,454 Altmetric mentions

Follow

Sign up for article alerts and news from this journal

BMC Genomics

ISSN: 1471-2164

Contact us