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  1. The rich genetic diversity in Citrullus lanatus and the other six species in the Citrullus genus provides important sources in watermelon breeding. Here, we present the Citrullus genus pan-genome based on the 400...

    Authors: Yang Sun, Dou-Rong Kou, Yan Li, Jiang-Ping Ni, Jing Wang, Yong-Mei Zhang, Qing-Nan Wang, Bin Jiang, Xu Wang, Yue-Xin Sun, Xin-Tong Xu, Xiao-Juan Tan, Yong-Jun Zhang and Xiang-dong Kong
    Citation: BMC Genomics 2023 24:332
    Content type: Research Published on:

  2. Physiological effects of ocean acidification associated with elevated CO2 concentrations in seawater is the subject of numerous studies in teleost fish. While the short time within-generation impact of ocean a...

    Authors: Pauline Auffret, Arianna Servili, Anne-Alicia Gonzalez, Marie-Lou Fleury, Felix Christopher Mark and David Mazurais
    Citation: BMC Genomics 2023 24:331
    Content type: Research Published on:

  3. Septoria tritici blotch (STB) remains a significant obstacle to durum wheat cultivation on a global scale. This disease remains a challenge for farmers, researchers, and breeders, who are collectively dedicate...

    Authors: Maroua Ouaja, Bochra A. Bahri, Sahbi Ferjaoui, Maher Medini, Udupa M. Sripada and Sonia Hamza
    Citation: BMC Genomics 2023 24:328
    Content type: Research Published on:

  4. White clover (Trifolium repens L.), an excellent perennial legume forage, is an allotetraploid native to southeastern Europe and southern Asia. It has high nutritional, ecological, genetic breeding, and medicinal...

    Authors: Hongjie Wang, Yongqiang Wu, Yong He, Guoyu Li, Lichao Ma, Shuo Li, Jianwei Huang and Guofeng Yang
    Citation: BMC Genomics 2023 24:326
    Content type: Research Published on:

  5. Premenopausal women diagnosed with breast cancer often face aggressive chemotherapy resulting in infertility. Tamoxifen (TAM) is a selective estrogen receptor modulator that was previously suggested as a prote...

    Authors: Anna Nynca, Sylwia Swigonska, Monika Ruszkowska, Agnieszka Sadowska, Karina Orlowska, Tomasz Molcan, Kamil Myszczynski, Iwona Otrocka-Domagala, Katarzyna Paździor-Czapula, Beata Kurowicka, Brian Kelli Petroff and Renata Elzbieta Ciereszko
    Citation: BMC Genomics 2023 24:325
    Content type: Research article Published on:

  6. Genome-wide association studies (GWASs) have identified many single-nucleotide polymorphisms (SNPs) associated with complex phenotypes in the European (EUR) population; however, the extent to which EUR-associa...

    Authors: Jiahao Qiao, Yuxuan Wu, Shuo Zhang, Yue Xu, Jinhui Zhang, Ping Zeng and Ting Wang
    Citation: BMC Genomics 2023 24:324
    Content type: Research Published on:

  7. Gastric cancer (GC) carries significant morbidity and mortality globally. An increasing number of studies have confirmed that circular RNA (circRNA) is tightly associated with the carcinogenesis and developmen...

    Authors: Jianing Yan, Guoliang Ye, Yanping Jin, Min Miao, Qier Li and Hanxuan Zhou
    Citation: BMC Genomics 2023 24:323
    Content type: Research Published on:

  8. GBA1 variants are the strongest genetic risk factor for Parkinson’s disease (PD). However, the pathogenicity of GBA1 variants concerning PD is still not fully understood. Additionally, the frequency of GBA1 varia...

    Authors: Carolin Gabbert, Susen Schaake, Theresa Lüth, Christoph Much, Christine Klein, Jan O. Aasly, Matthew J. Farrer and Joanne Trinh
    Citation: BMC Genomics 2023 24:322
    Content type: Research Published on:

  9. The Ustilaginales comprise hundreds of plant-parasitic fungi with a characteristic life cycle that directly links sexual reproduction and parasitism: One of the two mating-type loci codes for a transcription f...

    Authors: Lena Steins, Marco Alexandre Guerreiro, Marine Duhamel, Fei Liu, Qi-Ming Wang, Teun Boekhout and Dominik Begerow
    Citation: BMC Genomics 2023 24:321
    Content type: Research Published on:

  10. NIN-like protein (NLP) transcription factors (TFs) compose a plant-specific gene family whose members play vital roles in plant physiological processes, especially in the regulation of plant growth and the res...

    Authors: Jinqiu Yu, Yuying Yuan, Linling Dong and Guowen Cui
    Citation: BMC Genomics 2023 24:320
    Content type: Research Published on:

  11. There is still more to learn about the pathobiology of COVID-19. A multi-omic approach offers a holistic view to better understand the mechanisms of COVID-19. We used state-of-the-art statistical learning meth...

    Authors: Danika Lipman, Sandra E. Safo and Thierry Chekouo
    Citation: BMC Genomics 2023 24:319
    Content type: Research Published on:

  13. Yungui Plateau in Southwest China is characterized by multi-language and multi-ethnic communities and is one of the regions with the wealthiest ethnolinguistic, cultural and genetic diversity in East Asia. The...

    Authors: Jiawen Wang, Jun Wu, Qiuxia Sun, Qian Wu, Youjing Li, Shuhan Duan, Lin Yang, Wenxin Wu, Zheng Wang, Yan Liu, Renkuan Tang, Junbao Yang, Chuanchao Wang, Chao Liu, Jianwei Xu, Mengge Wang…
    Citation: BMC Genomics 2023 24:317
    Content type: Research Published on:

  14. In recent years, accumulating evidences have revealed that influenza A virus (IAV) infections induce significant differential expression of host long noncoding RNAs (lncRNAs), some of which play important role...

    Authors: Shengqiang Jiang, Jing Hu, Yang Bai, Ruiwei Hao, Long Liu and Hongying Chen
    Citation: BMC Genomics 2023 24:316
    Content type: Research Published on:

  15. Conflict between genes inherited from the mother (matrigenes) and the father (patrigenes) is predicted to arise during social interactions among offspring if these genes are not evenly distributed among offspr...

    Authors: Sean T. Bresnahan, Ellen Lee, Lindsay Clark, Rong Ma, Juliana Rangel, Christina M. Grozinger and Hongmei Li-Byarlay
    Citation: BMC Genomics 2023 24:315
    Content type: Research Published on:

  16. Genome-wide association studies have detected a large number of single-nucleotide polymorphisms (SNPs) associated with complex traits in diverse ancestral groups. However, the trans-ethnic similarity and diver...

    Authors: Jinhui Zhang, Shuo Zhang, Jiahao Qiao, Ting Wang and Ping Zeng
    Citation: BMC Genomics 2023 24:314
    Content type: Research Published on:

  17. Rewriting the genomes of living organisms has been a long-standing aim in the biological sciences. The revelation of the CRISPR/Cas9 technology has revolutionized the entire biological field. Since its emergen...

    Authors: Shiwei Zhou, Laura Johanna Lenk, Yawei Gao, Yuhui Wang, Xiaoe Zhao, Menghao Pan, Shuhong Huang, Kexin Sun, Peter Kalds, Qi Luo, Simon Lillico, Tad Sonstegard, Ute I. Scholl, Baohua Ma, Bjoern Petersen, Yulin Chen…
    Citation: BMC Genomics 2023 24:313
    Content type: Research Published on:

  18. The emergence and rapid spread of new severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) variants have challenged the control of the COVID-19 pandemic globally. Burundi was not spared by that pandemi...

    Authors: Cassien Nduwimana, Néhémie Nzoyikorera, Armstrong Ndihokubwayo, Théogène Ihorimbere, Célestin Nibogora, Adolphe Ndoreraho, Oscar Hajayandi, Jean Claude Bizimana, Idrissa Diawara, Dionis Niyonizigiye and Joseph Nyandwi
    Citation: BMC Genomics 2023 24:312
    Content type: Research Published on:

  19. Rapid adaptation to new environments can facilitate species invasions and range expansions. Understanding the mechanisms of adaptation used by invasive disease vectors in new regions has key implications for m...

    Authors: Shaghayegh Soudi, Marc Crepeau, Travis C. Collier, Yoosook Lee, Anthony J. Cornel and Gregory C. Lanzaro
    Citation: BMC Genomics 2023 24:311
    Content type: Research Published on:

  20. Cuscuta, a parasitic plant species in the Convolvulaceae family, grows in many countries and regions. However, the relationship between some species is still unclear. Therefore, more studies are needed to assess ...

    Authors: Hangkai Pan, Lyuben Zagorchev, Luxi Chen, Yutian Tao, Chaonan Cai, Ming Jiang, Zhongshuai Sun and Junmin Li
    Citation: BMC Genomics 2023 24:310
    Content type: Research Published on:

  21. The last decade has seen advancements in sequencing technologies and laboratory preparation protocols for ancient DNA (aDNA) that have rapidly been applied in multiple research areas thus enabling large-scale ...

    Authors: Ningbo Chen and Artem Nedoluzhko
    Citation: BMC Genomics 2023 24:309
    Content type: Editorial Published on:

  22. Rhesus macaques (Macaca mulatta, RMs) are widely used in sexual maturation studies due to their high genetic and physiological similarity to humans. However, judging sexual maturity in captive RMs based on blood ...

    Authors: Xu Liu, Xuyuan Liu, Xinqi Wang, Ke Shang, Jiawei Li, Yue Lan, Jiao Wang, Jing Li, Bisong Yue, Miao He and Zhenxin Fan
    Citation: BMC Genomics 2023 24:308
    Content type: Research Published on:

  23. Clear cell renal cell carcinoma (ccRCC) is a malignant tumor with heterogeneous morphology and poor prognosis. This study aimed to establish a DNA methylation (DNAm)-driven gene-based prognostic model for ccRCC.

    Authors: Qiong Deng, Ye Du, Zhu Wang, Yeda Chen, Jieyan Wang, Hui Liang and Du Zhang
    Citation: BMC Genomics 2023 24:307
    Content type: Research Published on:

  24. To overcome the ethical and technical limitations of in vivo human disease models, the broader scientific community frequently employs model organism-derived cell lines to investigate disease mechanisms, pathw...

    Authors: Rachel J. Boyd, Sarah A. McClymont, Nelson B. Barrientos, Paul W. Hook, William D. Law, Rebecca J. Rose, Eric L. Waite, Jay Rathinavelu, Dimitrios Avramopoulos and Andrew S. McCallion
    Citation: BMC Genomics 2023 24:306
    Content type: Research Published on:

  25. Our incomplete knowledge of the human transcriptome impairs the detection of disease-causing variants, in particular if they affect transcripts only expressed under certain conditions. These transcripts are of...

    Authors: Renee Salz, Nuno Saraiva-Agostinho, Emil Vorsteveld, Caspar I. van der Made, Simone Kersten, Merel Stemerdink, Jamie Allen, Pieter-Jan Volders, Sarah E. Hunt, Alexander Hoischen and Peter A.C. ’t Hoen
    Citation: BMC Genomics 2023 24:305
    Content type: Software Published on:

  26. Hereditary spherocytosis (HS) is a common inherited hemolytic anemia, caused by mutations in five genes that encode erythrocyte membrane skeleton proteins. The red blood cell (RBC) lifespan could directly refl...

    Authors: Yimeng Shi, Yuan Li, Xiawan Yang, Xiaoxia Li, Guangxin Peng, Xin Zhao, Xu Liu, Yufei Zhao, Jing Hu, Xiangrong Hu, Baohang Zhang, Kang Zhou, Yang Yang, Youzhen Xiong, Jianping Li, Huihui Fan…
    Citation: BMC Genomics 2023 24:304
    Content type: Research Published on:

  28. In light of previous studies that profiled breed-specific traits or used genome-wide association studies to refine loci associated with characteristic morphological features in dogs, the field has gained treme...

    Authors: Zicheng Li, Zuoheng Wang, Zhiyuan Chen, Heidi Voegeli, Judith H. Lichtman, Peter Smith, Ju Liu, Andrew T. DeWan and Josephine Hoh
    Citation: BMC Genomics 2023 24:302
    Content type: Research Published on:

  29. The behaviors and ontogeny of Aedes aegypti are closely related to the spread of diseases caused by dengue (DENV), chikungunya (CHIKV), Zika (ZIKV), and yellow fever (YFV) viruses. During the life cycle, Ae. aegy...

    Authors: Zhinan Lin, Yuqi Huang, Sihan Liu, Qiwen Huang, Biliang Zhang, Tianpeng Wang, Ziding Zhang, Xiaowei Zhu, Chenghong Liao and Qian Han
    Citation: BMC Genomics 2023 24:301
    Content type: Research Published on:

  30. There is a mutual hemodynamic and pathophysiological basis between the heart and brain. Glutamate (GLU) signaling plays an important role in the process of myocardial ischemia (MI) and ischemic stroke (IS). To...

    Authors: Wei Liao, Chunming He, Shaochun Yang, Man Zhou, Chuan Zeng, Muyun Luo, Junjian Yu, Shuo Hu, Yanyu Duan and Ziyou Liu
    Citation: BMC Genomics 2023 24:300
    Content type: Research Published on:

  31. Pueraria montana var. lobata (kudzu) is an important food and medicinal crop in Asia. However, the phylogenetic relationships between Pueraria montana var. lobata and the other two varieties (P. montana var. thom...

    Authors: Yun Zhou, Xiao-Hong Shang, Liang Xiao, Zheng-Dan Wu, Sheng Cao and Hua-Bing Yan
    Citation: BMC Genomics 2023 24:299
    Content type: Research Published on:

  32. Rabbits are well-domesticated animals. As a crucial economic animal, rabbit has been successfully bred into wool-use, meat-use and fur-use breeds. Hair length is one of the most economically important traits a...

    Authors: Nazira Fatima, Linying Jia, Baoning Liu, Lu Li, Liang Bai, Weirong Wang, Sihai Zhao, Rong Wang and Enqi Liu
    Citation: BMC Genomics 2023 24:298
    Content type: Research Published on:

  33. Saussurea involucrata (Sik.) is alpine plant that have developed special adaptive mechanisms to resist adverse environmental conditions such as low temperature chilling during long-term adaptation and evolution. ...

    Authors: Qi Sun, Lihua Ma and Xinxia Zhu
    Citation: BMC Genomics 2023 24:297
    Content type: Research Published on:

  34. Plant-parasitic nematodes (PPNs) that cause most damage include root-knot nematodes (RKNs) which are a major impediment to crop production. Root-knot nematodes, like other parasites, secrete proteins which are...

    Authors: Teresia Nyambura Macharia, Tuan A. Duong and Lucy Novungayo Moleleki
    Citation: BMC Genomics 2023 24:296
    Content type: Research Published on:

  36. Asthma is a common chronic respiratory disease worldwide. Recent studies have revealed the critical effects of the ceRNA network and ferroptosis on patients with asthma. Thus, this study aimed to explore the p...

    Authors: Shao-Tian Chen and Nan Yang
    Citation: BMC Genomics 2023 24:294
    Content type: Research Published on:

  37. As one of the important traits in pig production, meat quality has important research significance and value. Intramuscular fat (IMF) content is one of the most important factors affecting pork quality. Many e...

    Authors: Yingke Liu, Yilin Wei, Yaqing Dou, Chenlei Li, Chenglei Song, Zhe Zhang, Kunlong Qi, Xinjian Li, Ruimin Qiao, Kejun Wang, Xiuling Li, Feng Yang and Xuelei Han
    Citation: BMC Genomics 2023 24:293
    Content type: Research Published on:

  38. Feed restriction occurs frequently during pig growth, either due to economic reasons or stressful environmental conditions. Local breeds are suggested to have better tolerance to periods of feed restriction. H...

    Authors: Nausicaa Poullet, Orianne Devarieux, David Beramice, Laurent Dantec, Yoann Félicité, Dalila Feuillet, Jean-Luc Gourdine and Jean-Christophe Bambou
    Citation: BMC Genomics 2023 24:292
    Content type: Research Published on:

  39. Hong Kong catfish (Clarias fuscus) is an ecologically and economically important species that is widely distributed in freshwater regions of southern China. Hong Kong catfish has significant sexual growth dimorph...

    Authors: Chang-Xu Tian, Xing-Hua Lin, Da-Yan Zhou, Yu Chen, Yi-Jun Shen, Ming-Hui Ye, Cun-Yu Duan, Yu-Lei Zhang, Bin-Lan Yang, Si-Ping Deng, Chun-Hua Zhu and Guang-Li Li
    Citation: BMC Genomics 2023 24:291
    Content type: Research Published on:

  40. In the evolutionary study of gene families, exploring the duplication mechanisms of gene families helps researchers understand their evolutionary history. The tubby-like protein (TLP) family is essential for g...

    Authors: Huilong Chen, Yingchao Zhang and Shuyan Feng
    Citation: BMC Genomics 2023 24:290
    Content type: Research Published on:

  41. Recent advances in CRISPR technology have enabled us to perform gene knock-in in various species and cell lines. CRISPR-mediated knock-in requires donor DNA which serves as a template for homology-directed rep...

    Authors: Akira Mabuchi, Shoji Hata, Mariya Genova, Chiharu Tei, Kei K. Ito, Masayasu Hirota, Takuma Komori, Masamitsu Fukuyama, Takumi Chinen, Atsushi Toyoda and Daiju Kitagawa
    Citation: BMC Genomics 2023 24:289
    Content type: Research Published on:

  42. Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also...

    Authors: Konrad Sachse, Martin Hölzer, Fabien Vorimore, Lisa-Marie Barf, Carsten Sachse, Karine Laroucau, Manja Marz and Kevin Lamkiewicz
    Citation: BMC Genomics 2023 24:288
    Content type: Research Published on:

  43. DNA methylation is one of the most abundant epigenetic modifications, which plays important roles in flower development, sex differentiation, and regulation of flowering time. Its pattern is affected by cytosi...

    Authors: Qian Wang, Yinquan Qu, Yanhao Yu, Xia Mao and Xiangxiang Fu
    Citation: BMC Genomics 2023 24:287
    Content type: Research Published on:

  45. The genetic locus responsible for duck body size has been fully explained before, but the growth trait-related genetic basis is still waiting to be explored. For example, the genetic site related to growth rat...

    Authors: Yang Xi, Qifan Wu, Yutian Zeng, Jingjing Qi, Junpeng Li, Hua He, Hengyong Xu, Jiwei Hu, Xiping Yan, Lili Bai, Chunchun Han, Shenqiang Hu, Jiwen Wang, Hehe Liu and Liang Li
    Citation: BMC Genomics 2023 24:285
    Content type: Research Published on:

  46. Authors: Mishal Cohen‑Rengifo, Morgane Danion, Anne‑Alicia Gonzalez, Marie‑Laure Begout, Alexandre Cormier, Cyril Noel, Joelle Cabon, Thomas Vitre, Felix C. Mark and David Mazurais
    Citation: BMC Genomics 2023 24:284
    Content type: Correction Published on:

    The original article was published in BMC Genomics 2022 23:448

  47. Testis is the only organ supporting sperm production and with the largest number of proteins and tissue-specific proteins in animals. In our previous studies, we have found that knockdown of ocnus (ocn), a testis...

    Authors: Ya Zheng, Bin Mao, Qian Wang, Xin Duan, Meng-Yan Chen, Wei Shen, Chao Li and Yu-Feng Wang
    Citation: BMC Genomics 2023 24:283
    Content type: Research Published on:

  48. Cyclic nucleotide-gated ion channels (CNGCs) are nonselective cation channels that are ubiquitous in eukaryotic organisms. As Ca2+ channels, some CNGCs have also proven to be K+-permeable and involved in plant de...

    Authors: Nannan Zhang, Huanzhang Lin, Qiaoying Zeng, Danwen Fu, Xiaoning Gao, Jiayun Wu, Xiaomin Feng, Qinnan Wang, Qiuping Ling and Zilin Wu
    Citation: BMC Genomics 2023 24:281
    Content type: Research Published on:

  50. Piwi-interacting RNAs (piRNAs) have been proven to be closely associated with human diseases. The identification of the potential associations between piRNA and disease is of great significance for complex dis...

    Authors: Xianghan Meng, Junliang Shang, Daohui Ge, Yi Yang, Tongdui Zhang and Jin-Xing Liu
    Citation: BMC Genomics 2023 24:279
    Content type: Research Published on:

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BMC Genomics

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