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  1. Content type: Research article

    To control the osmotic pressure in the body, physiological adjustments to salinity fluctuations require the fish to regulate body fluid homeostasis in relation to environmental change via osmoregulation. Previ...

    Authors: Maoliang Su, Jianan Zhou, Zhengyu Duan and Junbin Zhang

    Citation: BMC Genomics 2019 20:418

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  2. Content type: Research article

    Mutations in the transcription factor, KLF1, are common within certain populations of the world. Heterozygous missense mutations in KLF1 mostly lead to benign phenotypes, but a heterozygous mutation in a DNA-bind...

    Authors: Melissa D. Ilsley, Stephen Huang, Graham W. Magor, Michael J. Landsberg, Kevin R. Gillinder and Andrew C. Perkins

    Citation: BMC Genomics 2019 20:417

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  3. Content type: Research article

    Lactobacillus brevis is a member of the lactic acid bacteria (LAB), and strains of L. brevis have been isolated from silage, as well as from fermented cabbage and other fermented foods. However, this bacterium is...

    Authors: Marine Feyereisen, Jennifer Mahony, Philip Kelleher, Richard John Roberts, Tadhg O’Sullivan, Jan-Maarten A. Geertman and Douwe van Sinderen

    Citation: BMC Genomics 2019 20:416

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  4. Content type: Research article

    Chinese giant salamander Andrias davidianus is an endangered species. The success of artificial breeding provides a useful way to protect this species. However, the method to identify the sex and mechanism of sex...

    Authors: Qiaomu Hu, Cuifang Chang, Quanhe Wang, Haifeng Tian, Zhigang Qiao, Lei Wang, Yan Meng, Cunshuan Xu and Hanbing Xiao

    Citation: BMC Genomics 2019 20:415

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  5. Content type: Research article

    Immediately after birth, the porcine intestine rapidly develops morphologically, functionally, and immunologically. The jejunum, the second part of the small intestine, is of importance for nutrient uptake and...

    Authors: Dirkjan Schokker, Ina Hulsegge, Henri Woelders and Johanna M. J. Rebel

    Citation: BMC Genomics 2019 20:414

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  6. Content type: Research article

    Parts of Europe and the United States have witnessed dramatic losses in commercially managed honey bees over the past decade to what is considered an unsustainable extent. The large-scale loss of bees has cons...

    Authors: Lindsay Rutter, Jimena Carrillo-Tripp, Bryony C. Bonning, Dianne Cook, Amy L. Toth and Adam G. Dolezal

    Citation: BMC Genomics 2019 20:412

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  7. Content type: Research article

    Trichophyton rubrum is the main etiological agent of skin and nail infections worldwide. Because of its keratinolytic activity and anthropophilic nature, infection models based on the addition of protein substrat...

    Authors: Tamires Aparecida Bitencourt, Claudia Macedo, Matheus Eloy Franco, Marina Campos Rocha, Igor Sawasaki Moreli, Bruna Aline Micheloto Cantelli, Pablo Rodrigo Sanches, Rene Oliveira Beleboni, Iran Malavazi, Geraldo Aleixo Passos, Mozart Marins and Ana Lúcia Fachin

    Citation: BMC Genomics 2019 20:411

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  8. Content type: Methodology article

    China has the richest local chicken breeding resources in the world and is the world’s second largest producer of meat-type chickens. Development of a moderate-density SNP array for genetic analysis of chicken...

    Authors: Ranran Liu, Siyuan Xing, Jie Wang, Maiqing Zheng, Huanxian Cui, Richard P. M. A. Crooijmans, Qinghe Li, Guiping Zhao and Jie Wen

    Citation: BMC Genomics 2019 20:410

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  9. Content type: Research article

    Our previous study described the crucial role of Rho-associated coiled-coil containing-kinases (ROCK) in hepatocellular carcinoma (HCC). However, the potential significance of long noncoding RNA downstream of ...

    Authors: He-Ming Zhou, Ji-Gang Zhang, Xue Zhang, Guo-Rong Fan, Gao-Lin Liu and Qin Li

    Citation: BMC Genomics 2019 20:409

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  10. Content type: Research article

    Overfeeding reduces laying performance in broiler breeder hens, which is associated with obesity, hepatic steatosis and systemic inflammation. To unravel the underlying mechanisms governing the effect of feedi...

    Authors: Zehui Wei, Pengcheng Li, Sijia Huang, Purevsuren Lkhagvagarav, Mengqi Zhu, Chuanyu Liang and Cunling Jia

    Citation: BMC Genomics 2019 20:408

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  11. Content type: Research article

    Magnetotactic bacteria (MTB) are ubiquitous in natural aquatic environments. MTB can produce intracellular magnetic particles, navigate along geomagnetic field, and respond to light. However, the potential mec...

    Authors: Yinzhao Wang, Giorgio Casaburi, Wei Lin, Ying Li, Fengping Wang and Yongxin Pan

    Citation: BMC Genomics 2019 20:407

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  12. Content type: Research article

    Cryptosporidiosis is a major cause of gastrointestinal diseases in humans and other vertebrates. Previous analyses of invasion-related proteins revealed that Cryptosporidium parvum, Cryptosporidium hominis, and C...

    Authors: Zhixiao Xu, Yaqiong Guo, Dawn M. Roellig, Yaoyu Feng and Lihua Xiao

    Citation: BMC Genomics 2019 20:406

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  13. Content type: Research article

    Fertility in dairy cows depends on ovarian cyclicity and on uterine involution. Ovarian cyclicity and uterine involution are delayed when there is uterine dysbiosis (overgrowth of pathogenic bacteria). Fertili...

    Authors: Stephen G. Moore, Aaron C. Ericsson, Susanta K. Behura, William R. Lamberson, Timothy J. Evans, Matthew S. McCabe, Scott E. Poock and Matthew C. Lucy

    Citation: BMC Genomics 2019 20:405

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  14. Content type: Research article

    Human milk oligosaccharides (OS) play a key role in brain and gut microbiota development of the neonate, but the underlying biosynthetic steps of OS in the mammary gland are still largely unknown. As bovine mi...

    Authors: Nina A. Poulsen, Randall C. Robinson, Daniela Barile, Lotte B. Larsen and Bart Buitenhuis

    Citation: BMC Genomics 2019 20:404

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  15. Content type: Research article

    Cotton (Gossypium spp.) is the most important natural fiber crop worldwide, and cottonseed oil is its most important byproduct. Phospholipid: diacylglycerol acyltransferase (PDAT) is important in TAG biosynthesis...

    Authors: Xinshan Zang, Xiaoli Geng, Lei Ma, Nuohan Wang, Wenfeng Pei, Man Wu, Jinfa Zhang and Jiwen Yu

    Citation: BMC Genomics 2019 20:402

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  16. Content type: Research article

    Through precise implementation of distinct cell type specification programs, differentially regulated in both space and time, complex patterns emerge during organogenesis. Thanks to its easy experimental acces...

    Authors: Christian Feregrino, Fabio Sacher, Oren Parnas and Patrick Tschopp

    Citation: BMC Genomics 2019 20:401

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  17. Content type: Research article

    In the mammary gland transcriptome of lactating dairy cows genes encoding milk proteins are highly abundant, which can impair the detection of lowly expressed transcripts and can bias the outcome in global tra...

    Authors: Johanna Brodhagen, Rosemarie Weikard, Ulrike Thom, Annika Heimes, Juliane Günther, Frieder Hadlich, Holm Zerbe, Wolfgang Petzl, Marie M. Meyerholz, Martina Hoedemaker, Hans-Joachim Schuberth, Susanne Engelmann and Christa Kühn

    Citation: BMC Genomics 2019 20:400

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  18. Content type: Research article

    The three epidemiologically important Opisthorchiidae liver flukes Opisthorchis felineus, O. viverrini, and Clonorchis sinensis, are believed to harbour similar potencies to provoke hepatobiliary diseases in thei...

    Authors: Nikita I. Ershov, Viatcheslav A. Mordvinov, Egor B. Prokhortchouk, Mariya Y. Pakharukova, Konstantin V. Gunbin, Kirill Ustyantsev, Mikhail A. Genaev, Alexander G. Blinov, Alexander Mazur, Eugenia Boulygina, Svetlana Tsygankova, Ekaterina Khrameeva, Nikolay Chekanov, Guangyi Fan, An Xiao, He Zhang…

    Citation: BMC Genomics 2019 20:399

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  19. Content type: Research article

    Salmonella enterica consists of over 2500 serovars and displays dichotomy in disease manifestations and host range. Except for the enrichment of pseudogenes in genomes for human-restricted serovars, no hallmark h...

    Authors: Ye Feng, Enze Lin, Shengmei Zou, Chyi-Liang Chen and Cheng-Hsun Chiu

    Citation: BMC Genomics 2019 20:398

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  20. Content type: Research article

    Phenotypic plasticity is a common and highly adaptive phenomenon where the same genotype produces different phenotypes in response to environmental cues. Sogatella furcifera, a migratory pest of rice exhibits win...

    Authors: Xinlei Gao, Yating Fu, Olugbenga Emmanuel Ajayi, Dongyang Guo, Liqin Zhang and Qingfa Wu

    Citation: BMC Genomics 2019 20:396

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  21. Content type: Research article

    Many genome-wide association studies have detected genomic regions associated with traits, yet understanding the functional causes of association often remains elusive. Utilizing systems approaches and focusin...

    Authors: Azam Yazdani, Akram Yazdani, Sarah H. Elsea, Daniel J. Schaid, Michael R. Kosorok, Gita Dangol and Ahmad Samiei

    Citation: BMC Genomics 2019 20:395

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  22. Content type: Research article

    The behavioural transition from nurses to foragers in honey bees is known to be affected by intrinsic and extrinsic factors, including colony demography, hormone levels, brain chemistry and structure, and gene...

    Authors: Fang Liu, Tengfei Shi, Lei Qi, Xin Su, Deqian Wang, Jie Dong and Zachary Y. Huang

    Citation: BMC Genomics 2019 20:393

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  23. Content type: Research article

    Peanut embryo development is a complex process involving a series of gene regulatory pathways and is easily affected by various elements in the soil. Calcium deficiency in the soil induces early embryo abortio...

    Authors: Hua Chen, Qiang Yang, Kun Chen, Shanshan Zhao, Chong Zhang, Ronglong Pan, Tiecheng Cai, Ye Deng, Xingjun Wang, Yuting Chen, Wenting Chu, Wenping Xie and Weijian Zhuang

    Citation: BMC Genomics 2019 20:392

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  24. Content type: Research article

    Phytohormones are key regulators of plant growth, development, and signalling networks involved in responses to diverse biotic and abiotic stresses. Transcriptional reference maps of hormone responses have bee...

    Authors: Peng-Fei Qi, Yun-Feng Jiang, Zhen-Ru Guo, Qing Chen, Thérèse Ouellet, Lu-Juan Zong, Zhen-Zhen Wei, Yan Wang, Ya-Zhou Zhang, Bin-Jie Xu, Li Kong, Mei Deng, Ji-Rui Wang, Guo-Yue Chen, Qian-Tao Jiang, Xiu-Jin Lan…

    Citation: BMC Genomics 2019 20:390

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  25. Content type: Research article

    Repeated culture reduces within-sample Mycobacterium tuberculosis genetic diversity due to selection of clones suited to growth in culture and/or random loss of lineages, but it is not known to what extent omitti...

    Authors: Camus Nimmo, Liam P. Shaw, Rona Doyle, Rachel Williams, Kayleen Brien, Carrie Burgess, Judith Breuer, Francois Balloux and Alexander S. Pym

    Citation: BMC Genomics 2019 20:389

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  26. Content type: Research article

    Hydrothermal vents and cold seeps are typical deep-sea chemosynthetically-driven ecosystems that allow high abundance of specialized macro-benthos. To gather knowledge about the genetic basis of adaptation to ...

    Authors: Jiao Cheng, Min Hui and Zhongli Sha

    Citation: BMC Genomics 2019 20:388

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  27. Content type: Database

    Scleractinian corals are important reef builders, but around the world they are under the threat of global climate change as well as local stressors. Molecular resources are critical for understanding a specie...

    Authors: Yanjie Zhang, Qian Chen, James Y. Xie, Yip Hung Yeung, Baohua Xiao, Baoling Liao, Jianliang Xu and Jian-Wen Qiu

    Citation: BMC Genomics 2019 20:387

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  28. Content type: Research article

    Adenovirus protein, Gam1, triggers the proteolytic destruction of the E1 SUMO-activating enzyme. Microinjection of an empirically determined amount of Gam1 mRNA into one-cell Xenopus embryos can reduce SUMOylatio...

    Authors: Michelle M. Bertke, Kyle M. Dubiak, Laura Cronin, Erliang Zeng and Paul W. Huber

    Citation: BMC Genomics 2019 20:386

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  29. Content type: Research article

    Narrow-leafed lupin is an emerging crop of significance in agriculture, livestock feed and human health food. However, its susceptibility to various diseases is a major obstacle towards increased adoption. Sclero...

    Authors: Mahsa Mousavi-Derazmahalleh, Steven Chang, Geoff Thomas, Mark Derbyshire, Phillip E. Bayer, David Edwards, Matthew N. Nelson, William Erskine, Francisco J. Lopez-Ruiz, Jon Clements and James K. Hane

    Citation: BMC Genomics 2019 20:385

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  30. Content type: Research article

    Panax ginseng C. A. Mey is one of famous medicinal herb plant species. Its major bioactive compounds are various ginsenosides in roots and rhizomes. It is commonly accepted that ginsenosides are synthesized from ...

    Authors: Le Xue, Zilong He, Xiaochun Bi, Wei Xu, Ting Wei, Shuangxiu Wu and Songnian Hu

    Citation: BMC Genomics 2019 20:383

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  31. Content type: Research article

    Several lines of evidence suggest that recombination plays a central role in replication and evolution of herpes simplex virus-1 (HSV-1). G-quadruplex (G4)-motifs have been linked to recombination events in hu...

    Authors: Nandhini Saranathan, Banhi Biswas, Anupam Patra and Perumal Vivekanandan

    Citation: BMC Genomics 2019 20:382

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  32. Content type: Research article

    Salinization seriously threatens land use efficiency and crop yields across the world. Understanding the mechanisms plants use to protect against salt stress will help breeders develop salt-tolerant vegetable ...

    Authors: Yihua Zhan, Qingfei Wu, Yue Chen, Mengling Tang, Chendong Sun, Junwei Sun and Chenliang Yu

    Citation: BMC Genomics 2019 20:381

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  33. Content type: Research article

    Discovering a genome-wide set of avocado (Persea americana Mill.) single nucleotide polymorphisms and characterizing the diversity of germplasm collection is a powerful tool for breeding. However, discovery is a ...

    Authors: Mor Rubinstein, Ravit Eshed, Ada Rozen, Tali Zviran, David N. Kuhn, Vered Irihimovitch, Amir Sherman and Ron Ophir

    Citation: BMC Genomics 2019 20:379

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  34. Content type: Research article

    Banana is one of the most important crops in tropical and sub-tropical regions. To meet the demands of international markets, banana plantations require high amounts of chemical fertilizers which translate int...

    Authors: Rocío M. Gamez, Fernando Rodríguez, Newton Medeiros Vidal, Sandra Ramirez, Roberto Vera Alvarez, David Landsman and Leonardo Mariño-Ramírez

    Citation: BMC Genomics 2019 20:378

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  35. Content type: Research article

    Copy number variations (CNVs), which are genetic variations present throughout mammalian genomes, are a vital source of phenotypic variation that can lead to the development of unique traits. In this study we ...

    Authors: Congjun Jia, Hongbo Wang, Chen Li, Xiaoyun Wu, Linsen Zan, Xuezhi Ding, Xian Guo, Pengjia Bao, Jie Pei, Min Chu, Chunnian Liang and Ping Yan

    Citation: BMC Genomics 2019 20:376

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  36. Content type: Research article

    Plant non-specific lipid transfer proteins (nsLTPs) are small, basic proteins that are abundant in higher plants. They have been reported to play an important role in various plant physiological processes, suc...

    Authors: Guojun Li, Menglu Hou, Yaxue Liu, Yue Pei, Minghui Ye, Yao Zhou, Chenxi Huang, Yaqi Zhao and Haoli Ma

    Citation: BMC Genomics 2019 20:375

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  37. Content type: Research article

    Phomafungin is a recently reported broad spectrum antifungal compound but its biosynthetic pathway is unknown. We combed publicly available Phoma genomes but failed to find any putative biosynthetic gene cluster ...

    Authors: Swati Sinha, Choy-Eng Nge, Chung Yan Leong, Veronica Ng, Sharon Crasta, Mohammad Alfatah, Falicia Goh, Kia-Ngee Low, Huibin Zhang, Prakash Arumugam, Alexander Lezhava, Swaine L. Chen, Yoganathan Kanagasundaram, Siew Bee Ng, Frank Eisenhaber and Birgit Eisenhaber

    Citation: BMC Genomics 2019 20:374

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  38. Content type: Research article

    Legumes can establish on nitrogen-deprived soils a symbiotic interaction with Rhizobia bacteria, leading to the formation of nitrogen-fixing root nodules. Cytokinin phytohormones are critical for triggering ro...

    Authors: Sovanna Tan, Frédéric Debellé, Pascal Gamas, Florian Frugier and Mathias Brault

    Citation: BMC Genomics 2019 20:373

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  39. Content type: Research article

    Barbarea vulgaris is a wild cruciferous plant and include two distinct types: the G- and P-types named after their glabrous and pubescent leaves, respectively. The types differ significantly in resistance to a ra...

    Authors: Tong-jin Liu, You-jun Zhang, Niels Agerbirk, Hai-ping Wang, Xiao-chun Wei, Jiang-ping Song, Hong-ju He, Xue-zhi Zhao, Xiao-hui Zhang and Xi-xiang Li

    Citation: BMC Genomics 2019 20:371

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  40. Content type: Research article

    Heat shock proteins have important functions in regulating plant growth and response to abiotic stress. HSP70 family genes have been described in several plant species, but a comprehensive analysis of the HSP70 f...

    Authors: Henan Su, Miaomiao Xing, Xing Liu, Zhiyuan Fang, Limei Yang, Mu Zhuang, Yangyong Zhang, Yong Wang and Honghao Lv

    Citation: BMC Genomics 2019 20:369

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  41. Content type: Research article

    Human papillomaviruses (HPVs) are genetically diverse, belonging to five distinct genera: Alpha, Beta, Gamma, Mu and Nu. All papillomaviruses have double stranded DNA genomes that are thought to evolve slowly ...

    Authors: Alltalents T. Murahwa, Fredrick Nindo, Harris Onywera, Tracy L. Meiring, Darren P. Martin and Anna-Lise Williamson

    Citation: BMC Genomics 2019 20:368

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  42. Content type: Research article

    Species of the Festuca and Lolium genera, as well as intergeneric Festuca × Lolium (Festulolium) hybrids, are valuable fodder and turf grasses for agricultural and amenity purposes worldwide. Festulolium hybrids ...

    Authors: Joanna Majka, Katarzyna Bzdęga, Agnieszka Janiak, Hanna Ćwiek-Kupczyńska, Paweł Krajewski, Tomasz Książczyk and Zbigniew Zwierzykowski

    Citation: BMC Genomics 2019 20:367

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  43. Content type: Research article

    There has been a steady increase in the number of studies aiming to identify DNA methylation differences associated with complex phenotypes. Many of the challenges of epigenetic epidemiology regarding study de...

    Authors: Georgina Mansell, Tyler J. Gorrie-Stone, Yanchun Bao, Meena Kumari, Leonard S. Schalkwyk, Jonathan Mill and Eilis Hannon

    Citation: BMC Genomics 2019 20:366

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