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  1. Bovine leukemia virus (BLV) is associated with enzootic bovine leukosis and is closely related to human T-cell leukemia virus type I. The Tax protein of BLV is a transcriptional activator of viral replication ...

    Authors: Mariluz Arainga, Eri Takeda and Yoko Aida
    Citation: BMC Genomics 2012 13:121
    Content type: Research article Published on:

  2. The sequence of the pathogen Mycobacterium tuberculosis (Mtb) strain H37Rv has been available for over a decade, but the biology of the pathogen remains poorly understood. Genome sequences from other Mtb strains ...

    Authors: Abigail Manson McGuire, Brian Weiner, Sang Tae Park, Ilan Wapinski, Sahadevan Raman, Gregory Dolganov, Matthew Peterson, Robert Riley, Jeremy Zucker, Thomas Abeel, Jared White, Peter Sisk, Christian Stolte, Mike Koehrsen, Robert T Yamamoto, Milena Iacobelli-Martinez…
    Citation: BMC Genomics 2012 13:120
    Content type: Research article Published on:

  3. In the silkworm, Bombyx mori, femaleness is strongly controlled by the female-specific W chromosome. Originally, it was presumed that the W chromosome encodes female-determining gene(s), accordingly called Fem. H...

    Authors: Kahori Hara, Tsuguru Fujii, Yutaka Suzuki, Sumio Sugano, Toru Shimada, Susumu Katsuma and Shinpei Kawaoka
    Citation: BMC Genomics 2012 13:119
    Content type: Research article Published on:

  4. A valuable tool for both research and industry, in vitro fertilization (IVF) has applications range from gamete selection and preservation of traits to cloning. Although IVF has achieved worldwide use, with ap...

    Authors: Ashley M Driver, Francisco Peñagaricano, Wen Huang, Khawaja R Ahmad, Katie S Hackbart, Milo C Wiltbank and Hasan Khatib
    Citation: BMC Genomics 2012 13:118
    Content type: Research article Published on:

  5. Expression traits can vary quantitatively between individuals and have a complex inheritance. Identification of the genetics underlying transcript variation can help in the understanding of phenotypic variatio...

    Authors: Francisco A Cubillos, Jennifer Yansouni, Hamid Khalili, Sandrine Balzergue, Samira Elftieh, Marie-Laure Martin-Magniette, Yann Serrand, Loïc Lepiniec, Sébastien Baud, Bertrand Dubreucq, Jean-Pierre Renou, Christine Camilleri and Olivier Loudet
    Citation: BMC Genomics 2012 13:117
    Content type: Research article Published on:

  6. In addition to genome sequencing, accurate functional annotation of genomes is required in order to carry out comparative and evolutionary analyses between species. Among primates, the human genome is the most...

    Authors: Michael Dannemann, Birgit Nickel, Esther Lizano, Hernán A Burbano and Janet Kelso
    Citation: BMC Genomics 2012 13:116
    Content type: Research article Published on:

  7. The placenta is a key component in understanding the physiological processes involved in pregnancy. Characterizing genes critical for placental function can serve as a basis for identifying mechanisms underlyi...

    Authors: Jinsil Kim, Keyan Zhao, Peng Jiang, Zhi-xiang Lu, Jinkai Wang, Jeffrey C Murray and Yi Xing
    Citation: BMC Genomics 2012 13:115
    Content type: Research article Published on:

  8. This study describes how the complete mitogenome of a terrestrial snail, Cylindrus obtusus (Draparnaud, 1805) was sequenced without PCRs from a collection specimen that had been in 70% ethanol for 8 years. The mi...

    Authors: Dick SJ Groenenberg, Walter Pirovano, Edmund Gittenberger and Menno Schilthuizen
    Citation: BMC Genomics 2012 13:114
    Content type: Methodology article Published on:

  9. Knowledge of germplasm diversity and relationships among elite breeding materials is fundamentally important in crop improvement. We genotyped 450 maize inbred lines developed and/or widely used by CIMMYT bree...

    Authors: Kassa Semagn, Cosmos Magorokosho, Bindiganavile S Vivek, Dan Makumbi, Yoseph Beyene, Stephen Mugo, BM Prasanna and Marilyn L Warburton
    Citation: BMC Genomics 2012 13:113
    Content type: Research article Published on:

  10. Actinoplanes sp. SE50/110 is known as the wild type producer of the alpha-glucosidase inhibitor acarbose, a potent drug used worldwide in the treatment of type-2 diabetes mellitus. As the incidence of diabetes is...

    Authors: Patrick Schwientek, Rafael Szczepanowski, Christian Rückert, Jörn Kalinowski, Andreas Klein, Klaus Selber, Udo F Wehmeier, Jens Stoye and Alfred Pühler
    Citation: BMC Genomics 2012 13:112
    Content type: Research article Published on:

  11. Different Cupriavidus metallidurans strains isolated from metal-contaminated and other anthropogenic environments were genotypically and phenotypically compared with C. metallidurans type strain CH34. The latter ...

    Authors: Rob Van Houdt, Pieter Monsieurs, Kristel Mijnendonckx, Ann Provoost, Ann Janssen, Max Mergeay and Natalie Leys
    Citation: BMC Genomics 2012 13:111
    Content type: Research article Published on:

  12. Dickeya dadantii and Pectobacterium atrosepticum are phytopathogenic enterobacteria capable of facultative anaerobic growth in a wide range of O2 concentrations found in plant and natural environments. The transc...

    Authors: Lavanya Babujee, Jennifer Apodaca, Venkatesh Balakrishnan, Paul Liss, Patricia J Kiley, Amy O Charkowski, Jeremy D Glasner and Nicole T Perna
    Citation: BMC Genomics 2012 13:110
    Content type: Research article Published on:

  13. Drosophila albomicans is a unique model organism for studying both sex chromosome and B chromosome evolution. A pair of its autosomes comprising roughly 40% of the whole genome has fused to the ancient X and Y ch...

    Authors: Qi Zhou, Hong-mei Zhu, Quan-fei Huang, Li Zhao, Guo-jie Zhang, Scott W Roy, Beatriz Vicoso, Zhao-lin Xuan, Jue Ruan, Yue Zhang, Ruo-ping Zhao, Chen Ye, Xiu-qing Zhang, Jun Wang, Wen Wang and Doris Bachtrog
    Citation: BMC Genomics 2012 13:109
    Content type: Research article Published on:

  16. Drug resistance in the malaria parasite Plasmodium falciparum severely compromises the treatment and control of malaria. A knowledge of the critical mutations conferring resistance to particular drugs is importan...

    Authors: Katarzyna Kinga Modrzynska, Alison Creasey, Laurence Loewe, Timothee Cezard, Sofia Trindade Borges, Axel Martinelli, Louise Rodrigues, Pedro Cravo, Mark Blaxter, Richard Carter and Paul Hunt
    Citation: BMC Genomics 2012 13:106
    Content type: Research article Published on:

  17. Biological systems respond to changes in both the Earth's magnetic and gravitational fields, but as experiments in space are expensive and infrequent, Earth-based simulation techniques are required. A high gra...

    Authors: Ana I Manzano, Jack JWA van Loon, Peter CM Christianen, Juana M Gonzalez-Rubio, F Javier Medina and Raul Herranz
    Citation: BMC Genomics 2012 13:105
    Content type: Research article Published on:

  18. Field pea (Pisum sativum L.) and faba bean (Vicia faba L.) are cool-season grain legume species that provide rich sources of food for humans and fodder for livestock. To date, both species have been relative 'gen...

    Authors: Sukhjiwan Kaur, Luke W Pembleton, Noel OI Cogan, Keith W Savin, Tony Leonforte, Jeffrey Paull, Michael Materne and John W Forster
    Citation: BMC Genomics 2012 13:104
    Content type: Research article Published on:

  19. Coffee trees (Rubiaceae) and tomato (Solanaceae) belong to the Asterid clade, while grapevine (Vitaceae) belongs to the Rosid clade. Coffee and tomato separated from grapevine 125 million years ago, while coff...

    Authors: Romain Guyot, Florent Lefebvre-Pautigny, Christine Tranchant-Dubreuil, Michel Rigoreau, Perla Hamon, Thierry Leroy, Serge Hamon, Valérie Poncet, Dominique Crouzillat and Alexandre de Kochko
    Citation: BMC Genomics 2012 13:103
    Content type: Research article Published on:

  20. Clostridium beijerinckii is a prominent solvent-producing microbe that has great potential for biofuel and chemical industries. Although transcriptional analysis is essential to understand gene functions and regu...

    Authors: Yi Wang, Xiangzhen Li, Yuejian Mao and Hans P Blaschek
    Citation: BMC Genomics 2012 13:102
    Content type: Research article Published on:

  21. Plants react to iron deficiency stress adopting different kind of adaptive responses. Tomato, a Strategy I plant, improves iron uptake through acidification of rhizosphere, reduction of Fe3+ to Fe2+ and transport...

    Authors: Anita Zamboni, Laura Zanin, Nicola Tomasi, Mario Pezzotti, Roberto Pinton, Zeno Varanini and Stefano Cesco
    Citation: BMC Genomics 2012 13:101
    Content type: Research article Published on:

  23. Sugar beet (Beta vulgaris sp. vulgaris) crops account for about 30% of world sugar. Sugar yield is compromised by reproductive growth hence crops must remain vegetative until harvest. Prolonged exposure to cold t...

    Authors: Effie S Mutasa-Göttgens, Anagha Joshi, Helen F Holmes, Peter Hedden and Berthold Göttgens
    Citation: BMC Genomics 2012 13:99
    Content type: Research article Published on:

  24. Marmosets are playing an increasingly large and important role in biomedical research. They share genetic, anatomical, and physiological similarities with humans and other primate model species, but their smal...

    Authors: Carolyn G Sweeney, Elizabeth Curran, Susan V Westmoreland, Keith G Mansfield and Eric J Vallender
    Citation: BMC Genomics 2012 13:98
    Content type: Research article Published on:

  25. In Drosophila melanogaster, the dosage-compensation system that equalizes X-linked gene expression between males and females, thereby assuring that an appropriate balance is maintained between the expression of g...

    Authors: Philge Philip, Fredrik Pettersson and Per Stenberg
    Citation: BMC Genomics 2012 13:97
    Content type: Research article Published on:

  26. Common carp (Cyprinus carpio) is thought to have undergone one extra round of genome duplication compared to zebrafish. Transcriptome analysis has been used to study the existence and timing of genome duplication...

    Authors: Jin-Tu Wang, Jiong-Tang Li, Xiao-Feng Zhang and Xiao-Wen Sun
    Citation: BMC Genomics 2012 13:96
    Content type: Research article Published on:

  27. High-density linkage maps facilitate the mapping of target genes and the construction of partial linkage maps around target loci to develop markers for marker-assisted selection (MAS). MAS is quite challenging...

    Authors: Yoshinari Moriguchi, Tokuko Ujino-Ihara, Kentaro Uchiyama, Norihiro Futamura, Maki Saito, Saneyoshi Ueno, Asako Matsumoto, Naoki Tani, Hideaki Taira, Kenji Shinohara and Yoshihiko Tsumura
    Citation: BMC Genomics 2012 13:95
    Content type: Research article Published on:

  28. Genome-wide gene expression profiling and detailed physiological investigation were used for understanding the molecular mechanism and physiological response of Gossypium herbaceum, which governs the adaptability...

    Authors: Alok Ranjan, Deepti Nigam, Mehar H Asif, Ruchi Singh, Sanjay Ranjan, Shrikant Mantri, Neha Pandey, Ila Trivedi, Krishan Mohan Rai, Satya N Jena, Bhupendra Koul, Rakesh Tuli, Uday V Pathre and Samir V Sawant
    Citation: BMC Genomics 2012 13:94
    Content type: Research article Published on:

  29. In rodent models and in humans the impact of gestational diets on the offspring's phenotype was shown experimentally and epidemiologically. Adverse environmental conditions during fetal development provoke an ...

    Authors: Michael Oster, Eduard Murani, Cornelia C Metges, Siriluck Ponsuksili and Klaus Wimmers
    Citation: BMC Genomics 2012 13:93
    Content type: Research article Published on:

  30. Transcriptome analysis is increasingly being used to study the evolutionary origins and ecology of non-model plants. One issue for both transcriptome assembly and differential gene expression analyses is the c...

    Authors: Nicole Gruenheit, Oliver Deusch, Christian Esser, Matthias Becker, Claudia Voelckel and Peter Lockhart
    Citation: BMC Genomics 2012 13:92
    Content type: Research article Published on:

  31. A central goal in Huntington's disease (HD) research is to identify and prioritize candidate targets for neuroprotective intervention, which requires genome-scale information on the modifiers of early-stage ne...

    Authors: François-Xavier Lejeune, Lilia Mesrob, Frédéric Parmentier, Cedric Bicep, Rafael P Vazquez-Manrique, J Alex Parker, Jean-Philippe Vert, Cendrine Tourette and Christian Neri
    Citation: BMC Genomics 2012 13:91
    Content type: Research article Published on:

  32. The peanut (Arachis hypogaea L.) is an important oilseed crop in tropical and subtropical regions of the world. However, little about the molecular biology of the peanut is currently known. Recently, next-generat...

    Authors: Jianan Zhang, Shan Liang, Jialei Duan, Jin Wang, Silong Chen, Zengshu Cheng, Qiang Zhang, Xuanqiang Liang and Yurong Li
    Citation: BMC Genomics 2012 13:90
    Content type: Research article Published on:

  33. The genome of Mycobacterium avium subspecies paratuberculosis (MAP) is remarkably homogeneous among the genomes of bovine, human and wildlife isolates. However, previous work in our laboratories with the bovine K...

    Authors: John P Bannantine, Chia-wei Wu, Chungyi Hsu, Shiguo Zhou, David C Schwartz, Darrell O Bayles, Michael L Paustian, David P Alt, Srinand Sreevatsan, Vivek Kapur and Adel M Talaat
    Citation: BMC Genomics 2012 13:89
    Content type: Research article Published on:

  34. Technological advances in high throughput genome sequencing are making whole genome sequencing (WGS) available as a routine tool for bacterial typing. Standardized procedures for identification of relevant gen...

    Authors: Pimlapas Leekitcharoenphon, Oksana Lukjancenko, Carsten Friis, Frank M Aarestrup and David W Ussery
    Citation: BMC Genomics 2012 13:88
    Content type: Research article Published on:

  35. The Tasmanian devil (Sarcophilus harrisii) is currently under threat of extinction due to an unusual fatal contagious cancer called Devil Facial Tumour Disease (DFTD). DFTD is caused by a clonal tumour cell line ...

    Authors: Yuanyuan Cheng, Andrew Stuart, Katrina Morris, Robyn Taylor, Hannah Siddle, Janine Deakin, Menna Jones, Chris T Amemiya and Katherine Belov
    Citation: BMC Genomics 2012 13:87
    Content type: Research article Published on:

  38. Small intestine and liver greatly contribute to whole body lipid, cholesterol and phospholipid metabolism but to which extent cholesterol and phospholipid handling in these tissues is affected by high fat West...

    Authors: Charles Desmarchelier, Christoph Dahlhoff, Sylvia Keller, Manuela Sailer, Gerhard Jahreis and Hannelore Daniel
    Citation: BMC Genomics 2012 13:84
    Content type: Research article Published on:

  39. MicroRNAs (miRNAs) are endogenously encoded small RNAs that post-transcriptionally regulate gene expression. MiRNAs play essential roles in almost all plant biological processes. Currently, few miRNAs have bee...

    Authors: Pablo Peláez, Minerva S Trejo, Luis P Iñiguez, Georgina Estrada-Navarrete, Alejandra A Covarrubias, José L Reyes and Federico Sanchez
    Citation: BMC Genomics 2012 13:83
    Content type: Research article Published on:

  40. The small airway epithelium (SAE), the cell population that covers the human airway surface from the 6th generation of airway branching to the alveoli, is the major site of lung disease caused by smoking. The foc...

    Authors: Neil R Hackett, Marcus W Butler, Renat Shaykhiev, Jacqueline Salit, Larsson Omberg, Juan L Rodriguez-Flores, Jason G Mezey, Yael Strulovici-Barel, Guoqing Wang, Lukas Didon and Ronald G Crystal
    Citation: BMC Genomics 2012 13:82
    Content type: Research article Published on:

  41. There has been an increasing body of epidemiologic and biochemical evidence implying the role of cerebral insulin resistance in Alzheimer-type dementia. For a better understanding of the insulin effect on the ...

    Authors: Omar Abdul-Rahman, Maria Sasvari-Szekely, Agota Ver, Klara Rosta, Bernadett K Szasz, Eva Kereszturi and Gergely Keszler
    Citation: BMC Genomics 2012 13:81
    Content type: Research article Published on:

  42. Cucurbita pepo is a member of the Cucurbitaceae family, the second- most important horticultural family in terms of economic importance after Solanaceae. The "summer squash" types, including Zucchini and Scallop,...

    Authors: Cristina Esteras, Pedro Gómez, Antonio J Monforte, José Blanca, Nelly Vicente-Dólera, Cristina Roig, Fernando Nuez and Belén Picó
    Citation: BMC Genomics 2012 13:80
    Content type: Research article Published on:

  43. The importance of peptide microarrays as a tool for serological diagnostics has strongly increased over the last decade. However, interpretation of the binding signals is still hampered by our limited understa...

    Authors: Victor Greiff, Henning Redestig, Juliane Lück, Nicole Bruni, Atijeh Valai, Susanne Hartmann, Sebastian Rausch, Johannes Schuchhardt and Michal Or-Guil
    Citation: BMC Genomics 2012 13:79
    Content type: Research article Published on:

  44. The catalog of genetic variants in the horse genome originates from a few select animals, the majority originating from the Thoroughbred mare used for the equine genome sequencing project. The purpose of this ...

    Authors: Ryan Doan, Noah D Cohen, Jason Sawyer, Noushin Ghaffari, Charles D Johnson and Scott V Dindot
    Citation: BMC Genomics 2012 13:78
    Content type: Research article Published on:

  45. Restriction Enzyme-based Reduced Representation Library (RRL) method represents a relatively feasible and flexible strategy used for Single Nucleotide Polymorphism (SNP) identification in different species. It...

    Authors: Ye Du, Hui Jiang, Ying Chen, Cong Li, Meiru Zhao, Jinghua Wu, Yong Qiu, Qibin Li and Xiuqing Zhang
    Citation: BMC Genomics 2012 13:77
    Content type: Research article Published on:

  46. Although sexual reproduction is dominant within eukaryotes, asexual reproduction is widespread and has evolved independently as a derived trait in almost all major taxa. How asexuality evolved in sexual organi...

    Authors: Aurore Gallot, Shuji Shigenobu, Tomomi Hashiyama, Stéphanie Jaubert-Possamai and Denis Tagu
    Citation: BMC Genomics 2012 13:76
    Content type: Research article Published on:

  47. The potato genome sequence derived from the Solanum tuberosum Group Phureja clone DM1-3 516 R44 provides unparalleled insight into the genome composition and organisation of this important crop. A key class of ge...

    Authors: Florian Jupe, Leighton Pritchard, Graham J Etherington, Katrin MacKenzie, Peter JA Cock, Frank Wright, Sanjeev Kumar Sharma, Dan Bolser, Glenn J Bryan, Jonathan DG Jones and Ingo Hein
    Citation: BMC Genomics 2012 13:75
    Content type: Research article Published on:

  49. The structural and functional annotation of genomes is now heavily based on data obtained using automated pipeline systems. The key for an accurate structural annotation consists of blending similarities betwe...

    Authors: Joseph A Christie-Oleza, Guylaine Miotello and Jean Armengaud
    Citation: BMC Genomics 2012 13:73
    Content type: Research article Published on:

  50. The evolution of sociality in spiders involves a transition from an outcrossing to a highly inbreeding mating system, a shift to a female biased sex ratio, and an increase in the reproductive skew among indivi...

    Authors: Tiina M Mattila, Jesper S Bechsgaard, Troels T Hansen, Mikkel H Schierup and Trine Bilde
    Citation: BMC Genomics 2012 13:70
    Content type: Research article Published on:

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BMC Genomics

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