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  1. New chemotherapeutic agents against Schistosoma mansoni, an etiological agent of human schistosomiasis, are a priority due to the emerging drug resistance and the inability of current drug treatments to prevent r...

    Authors: David H Bos, Chris Mayfield and Dennis J Minchella
    Citation: BMC Genomics 2009 10:488
  2. The silkworm, Bombyx mori, is one of the most economically important insects in many developing countries owing to its large-scale cultivation for silk production. With the development of genomic and biotechnolog...

    Authors: Michihiko Shimomura, Hiroshi Minami, Yoshitaka Suetsugu, Hajime Ohyanagi, Chikatada Satoh, Baltazar Antonio, Yoshiaki Nagamura, Keiko Kadono-Okuda, Hideyuki Kajiwara, Hideki Sezutsu, Javaregowda Nagaraju, Marian R Goldsmith, Qingyou Xia, Kimiko Yamamoto and Kazuei Mita
    Citation: BMC Genomics 2009 10:486
  3. Rare population variants are known to have important biomedical implications, but their systematic discovery has only recently been enabled by advances in DNA sequencing. The design process of a discovery proj...

    Authors: Michael C Wendl and Richard K Wilson
    Citation: BMC Genomics 2009 10:485
  4. How photosynthetic organelles, or plastids, were acquired by diverse eukaryotes is among the most hotly debated topics in broad scale eukaryotic evolution. The history of plastid endosymbioses commonly is inte...

    Authors: John W Stiller, Jinling Huang, Qin Ding, Jing Tian and Carol Goodwillie
    Citation: BMC Genomics 2009 10:484
  5. Several global transcriptomic and proteomic approaches have been applied in order to obtain new molecular insights on skeletal myogenesis, but none has generated any specific data on glycogenome expression, an...

    Authors: Mathilde Janot, Aymeric Audfray, Céline Loriol, Agnès Germot, Abderrahman Maftah and Fabrice Dupuy
    Citation: BMC Genomics 2009 10:483
  6. Trypanosoma brucei, the causative agent of African sleeping sickness, undergoes a complex developmental cycle that takes place in mammalian and insect hosts and is accompanied by changes in metabolism and cellula...

    Authors: Bryan C Jensen, Dhileep Sivam, Charles T Kifer, Peter J Myler and Marilyn Parsons
    Citation: BMC Genomics 2009 10:482
  7. During gut colonization, the enteric pathogen Campylobacter jejuni must surmount the toxic effects of reactive oxygen species produced by its own metabolism, the host immune system, and intestinal microflora. Elu...

    Authors: Kiran Palyada, Yi-Qian Sun, Annika Flint, James Butcher, Hemant Naikare and Alain Stintzi
    Citation: BMC Genomics 2009 10:481
  8. Pseudogenes provide a record of the molecular evolution of genes. As glycolysis is such a highly conserved and fundamental metabolic pathway, the pseudogenes of glycolytic enzymes comprise a standardized genom...

    Authors: Yuen-Jong Liu, Deyou Zheng, Suganthi Balasubramanian, Nicholas Carriero, Ekta Khurana, Rebecca Robilotto and Mark B Gerstein
    Citation: BMC Genomics 2009 10:480
  9. The development of second generation sequencing methods has enabled large scale DNA variation studies at moderate cost. For the high throughput discovery of single nucleotide polymorphisms (SNPs) in species la...

    Authors: Hindrik HD Kerstens, Richard PMA Crooijmans, Albertine Veenendaal, Bert W Dibbits, Thomas FC Chin-A-Woeng, Johan T den Dunnen and Martien AM Groenen
    Citation: BMC Genomics 2009 10:479
  10. miRNAs play important roles in the regulation of gene functions. Maternal dietary modifications during pregnancy and gestation have long-term effects on the offspring, but it is not known whether a maternal hi...

    Authors: Junlong Zhang, Fang Zhang, Xavier Didelot, Kimberley D Bruce, Felino R Cagampang, Manu Vatish, Mark Hanson, Hendrik Lehnert, Antonio Ceriello and Christopher D Byrne
    Citation: BMC Genomics 2009 10:478
  11. Bacterial artificial chromosomes (BACs) are among the most widely used tools for studies of gene regulation and function in model vertebrates, yet methods for predictable delivery of BAC transgenes to the geno...

    Authors: Maximiliano L Suster, Kenta Sumiyama and Koichi Kawakami
    Citation: BMC Genomics 2009 10:477
  12. The development and maintenance of the prostate is dependent on androgens and the androgen receptor. The androgen pathway continues to be important in prostate cancer. Here, we evaluated the transcriptome of p...

    Authors: Tammy L Romanuik, Gang Wang, Robert A Holt, Steven JM Jones, Marco A Marra and Marianne D Sadar
    Citation: BMC Genomics 2009 10:476
  13. Meiotic recombination alters frequency and distribution of genetic variation, impacting genetics and evolution. In the budding yeast, DNA double strand breaks (DSBs) and D loops form either crossovers (COs) or...

    Authors: Ji Qi, Asela J Wijeratne, Lynn P Tomsho, Yi Hu, Stephan C Schuster and Hong Ma
    Citation: BMC Genomics 2009 10:475
  14. Gene expression signatures are clusters of genes discriminating different statuses of the cells and their definition is critical for understanding the molecular bases of diseases. The identification of a gene ...

    Authors: Paolo Fardin, Annalisa Barla, Sofia Mosci, Lorenzo Rosasco, Alessandro Verri and Luigi Varesio
    Citation: BMC Genomics 2009 10:474
  15. Grasses are among the most important and widely cultivated plants on Earth. They provide high quality fodder for livestock, are used for turf and amenity purposes, and play a fundamental role in environment pr...

    Authors: David Kopecký, Jan Bartoš, Adam J Lukaszewski, James H Baird, Vladimír Černoch, Roland Kölliker, Odd Arne Rognli, Helene Blois, Vanessa Caig, Thomas Lübberstedt, Bruno Studer, Paul Shaw, Jaroslav Doležel and Andrzej Kilian
    Citation: BMC Genomics 2009 10:473
  16. Epigenetic modification of DNA via methylation is one of the key inventions in eukaryotic evolution. It provides a source for the switching of gene activities, the maintenance of stable phenotypes and the inte...

    Authors: Sylvain Foret, Robert Kucharski, Yvonne Pittelkow, Gabrielle A Lockett and Ryszard Maleszka
    Citation: BMC Genomics 2009 10:472
  17. Microarrays are an invaluable tool in many modern genomic studies. It is generally perceived that decreasing the size of microarray features leads to arrays with higher resolution (due to greater feature densi...

    Authors: Ron Ammar, Andrew M Smith, Lawrence E Heisler, Guri Giaever and Corey Nislow
    Citation: BMC Genomics 2009 10:471
  18. COG0523 proteins are, like the nickel chaperones of the UreG family, part of the G3E family of GTPases linking them to metallocenter biosynthesis. Even though the first COG0523-encoding gene, cobW, was identified...

    Authors: Crysten E Haas, Dmitry A Rodionov, Janette Kropat, Davin Malasarn, Sabeeha S Merchant and Valérie de Crécy-Lagard
    Citation: BMC Genomics 2009 10:470
  19. Tardigrades represent an animal phylum with extraordinary resistance to environmental stress.

    Authors: Frank Förster, Chunguang Liang, Alexander Shkumatov, Daniela Beisser, Julia C Engelmann, Martina Schnölzer, Marcus Frohme, Tobias Müller, Ralph O Schill and Thomas Dandekar
    Citation: BMC Genomics 2009 10:469
  20. Genome analysis of three Frankia sp. strains has revealed a high number of transposable elements in two of the strains. Twelve out of the 20 major families of bacterial Insertion Sequence (IS) elements are repres...

    Authors: Derek M Bickhart, Johann P Gogarten, Pascal Lapierre, Louis S Tisa, Philippe Normand and David R Benson
    Citation: BMC Genomics 2009 10:468
  21. Melon (Cucumis melo) is a horticultural specie of significant nutritional value, which belongs to the Cucurbitaceae family, whose economic importance is second only to the Solanaceae. Its small genome of approx. ...

    Authors: Albert Mascarell-Creus, Joaquin Cañizares, Josep Vilarrasa-Blasi, Santiago Mora-García, José Blanca, Daniel Gonzalez-Ibeas, Montserrat Saladié, Cristina Roig, Wim Deleu, Belén Picó-Silvent, Nuria López-Bigas, Miguel A Aranda, Jordi Garcia-Mas, Fernando Nuez, Pere Puigdomènech and Ana I Caño-Delgado
    Citation: BMC Genomics 2009 10:467
  22. Cultivated tomato (Solanum lycopersicum L.) has narrow genetic diversity that makes it difficult to identify polymorphisms between elite germplasm. We explored array-based single feature polymorphism (SFP) discov...

    Authors: Sung-Chur Sim, Matthew D Robbins, Charles Chilcott, Tong Zhu and David M Francis
    Citation: BMC Genomics 2009 10:466
  23. Glandular trichomes produce a wide variety of commercially important secondary metabolites in many plant species. The most prominent anti-malarial drug artemisinin, a sesquiterpene lactone, is produced in glan...

    Authors: Wei Wang, Yejun Wang, Qing Zhang, Yan Qi and Dianjing Guo
    Citation: BMC Genomics 2009 10:465
  24. Schistosomes are trematode parasites of the phylum Platyhelminthes. They are considered the most important of the human helminth parasites in terms of morbidity and mortality. Draft genome sequences are now av...

    Authors: Claudia S Copeland, Manja Marz, Dominic Rose, Jana Hertel, Paul J Brindley, Clara Bermudez Santana, Stephanie Kehr, Camille Stephan-Otto Attolini and Peter F Stadler
    Citation: BMC Genomics 2009 10:464
  25. Genome sequences can be conceptualized as arrangements of motifs or words. The frequencies and positional distributions of these words within particular non-coding genomic segments provide important insights i...

    Authors: Jens Lichtenberg, Alper Yilmaz, Joshua D Welch, Kyle Kurz, Xiaoyu Liang, Frank Drews, Klaus Ecker, Stephen S Lee, Matt Geisler, Erich Grotewold and Lonnie R Welch
    Citation: BMC Genomics 2009 10:463
  26. Rainbow trout (Oncorhynchus mykiss) are the most-widely cultivated cold freshwater fish in the world and an important model species for many research areas. Coupling great interest in this species as a research m...

    Authors: Yniv Palti, Ming-Cheng Luo, Yuqin Hu, Carine Genet, Frank M You, Roger L Vallejo, Gary H Thorgaard, Paul A Wheeler and Caird E Rexroad III
    Citation: BMC Genomics 2009 10:462
  27. The industrially important yeast Saccharomyces cerevisiae is able to grow both in the presence and absence of oxygen. However, the regulation of its metabolism in conditions of intermediate oxygen availability is...

    Authors: Eija Rintala, Mervi Toivari, Juha-Pekka Pitkänen, Marilyn G Wiebe, Laura Ruohonen and Merja Penttilä
    Citation: BMC Genomics 2009 10:461
  28. Phytoplasmas are bacteria without cell walls from the class Mollicutes. They are obligate intracellular plant pathogens which cause diseases in hundreds of economically important plants including the grapevine (V...

    Authors: Matjaž Hren, Petra Nikolić, Ana Rotter, Andrej Blejec, Nancy Terrier, Maja Ravnikar, Marina Dermastia and Kristina Gruden
    Citation: BMC Genomics 2009 10:460
  29. Pleiotropic Drug Resistant transporters (PDR) are members of the ATP-Binding Cassette (ABC) subfamily which export antifungals and other xenobiotics in fungi and plants. This subfamily of transmembrane transpo...

    Authors: Marie-Line Seret, Julie F Diffels, André Goffeau and Philippe V Baret
    Citation: BMC Genomics 2009 10:459
  30. Triticum monococcum (2n = 2x = 14) is an ancient diploid wheat with many useful traits and is used as a model for wheat gene discovery. DArT (D iversity Ar rays T echnology) employs a hybridisation-based approach...

    Authors: Hai-Chun Jing, Carlos Bayon, Kostya Kanyuka, Simon Berry, Peter Wenzl, Eric Huttner, Andrzej Kilian and Kim E Hammond-Kosack
    Citation: BMC Genomics 2009 10:458
  31. Cotton (Gossypium hirsutum) is one of the most important economic crops and provides excellent fibers for textile manufacture. In addition to its industrial and agricultural importance, the fiber cell (plant tric...

    Authors: Pieter Bas Kwak, Qin Qin Wang, Xu Sheng Chen, Cheng Xiang Qiu and Zhi Min Yang
    Citation: BMC Genomics 2009 10:457
  32. Aphid adaptation to harsh winter conditions is illustrated by an alternation of their reproductive mode. Aphids detect photoperiod shortening by sensing the length of the night and switch from viviparous parth...

    Authors: G Le Trionnaire, F Francis, S Jaubert-Possamai, J Bonhomme, E De Pauw, J-P Gauthier, E Haubruge, F Legeai, N Prunier-Leterme, J-C Simon, S Tanguy and D Tagu
    Citation: BMC Genomics 2009 10:456
  33. MicroRNAs (miRNAs) are expressed by a wide range of eukaryotic organisms, and function in diverse biological processes. Numerous miRNAs have been identified in Bombyx mori, but the temporal expression profiles of...

    Authors: Shiping Liu, Liang Zhang, Qibin Li, Ping Zhao, Jun Duan, Daojun Cheng, Zhonghuai Xiang and Qingyou Xia
    Citation: BMC Genomics 2009 10:455

    The Retraction Note to this article has been published in BMC Genomics 2011 12:284

  34. The globe artichoke (Cynara cardunculus var. scolymus L.) is a significant crop in the Mediterranean basin. Despite its commercial importance and its both dietary and pharmaceutical value, knowledge of its geneti...

    Authors: Davide Scaglione, Alberto Acquadro, Ezio Portis, Christopher A Taylor, Sergio Lanteri and Steven J Knapp
    Citation: BMC Genomics 2009 10:454
  35. There is little information about the DNA sequence variation within and between closely related plant species. The combination of re-sequencing technologies, large-scale DNA pools and availability of reference...

    Authors: Carsten Külheim, Suat Hui Yeoh, Jens Maintz, William J Foley and Gavin F Moran
    Citation: BMC Genomics 2009 10:452
  36. The freshwater snail Lymnaea stagnalis (L. stagnalis) has served as a successful model for studies in the field of Neuroscience. However, a serious drawback in the molecular analysis of the nervous system of L. s...

    Authors: Z-P Feng, Z Zhang, RE van Kesteren, VA Straub, P van Nierop, K Jin, N Nejatbakhsh, JI Goldberg, GE Spencer, MS Yeoman, W Wildering, JR Coorssen, RP Croll, LT Buck, NI Syed and AB Smit
    Citation: BMC Genomics 2009 10:451
  37. Gluconacetobacter diazotrophicus Pal5 is an endophytic diazotrophic bacterium that lives in association with sugarcane plants. It has important biotechnological features such as nitrogen fixation, plant growth pr...

    Authors: Marcelo Bertalan, Rodolpho Albano, Vânia de Pádua, Luc Rouws, Cristian Rojas, Adriana Hemerly, Kátia Teixeira, Stefan Schwab, Jean Araujo, André Oliveira, Leonardo França, Viviane Magalhães, Sylvia Alquéres, Alexander Cardoso, Welington Almeida, Marcio Martins Loureiro…
    Citation: BMC Genomics 2009 10:450
  38. MicroRNAs (miRNAs) are endogenous small RNAs having large-scale regulatory effects on plant development and stress responses. Extensive studies of miRNAs have only been performed in a few model plants. Althoug...

    Authors: Jingyu Zhang, Yunyuan Xu, Qing Huan and Kang Chong
    Citation: BMC Genomics 2009 10:449
  39. Systemic administration of β-adrenoceptor (β-AR) agonists has been found to induce skeletal muscle hypertrophy and significant metabolic changes. In the context of energy homeostasis, the importance of β-AR si...

    Authors: Michael A Pearen, James G Ryall, Gordon S Lynch and George EO Muscat
    Citation: BMC Genomics 2009 10:448
  40. Rhodoferax ferrireducens is a metabolically versatile, Fe(III)-reducing, subsurface microorganism that is likely to play an important role in the carbon and metal cycles in the subsurface. It also has the unique ...

    Authors: Carla Risso, Jun Sun, Kai Zhuang, Radhakrishnan Mahadevan, Robert DeBoy, Wael Ismail, Susmita Shrivastava, Heather Huot, Sagar Kothari, Sean Daugherty, Olivia Bui, Christophe H Schilling, Derek R Lovley and Barbara A Methé
    Citation: BMC Genomics 2009 10:447
  41. The detection of odorants is mediated by olfactory receptors (ORs). ORs are G-protein coupled receptors that form a remarkably large protein superfamily in vertebrate genomes. We used data that became availabl...

    Authors: Silke S Steiger, Vladimir Y Kuryshev, Marcus C Stensmyr, Bart Kempenaers and Jakob C Mueller
    Citation: BMC Genomics 2009 10:446
  42. Subtelomeric RIFIN genes constitute the most abundant multigene family in Plasmodium falciparum. RIFIN products are targets for the human immune response and contribute to the antigenic variability of the parasit...

    Authors: Emanuele Bultrini, Kevin Brick, Srayanta Mukherjee, Yang Zhang, Francesco Silvestrini, Pietro Alano and Elisabetta Pizzi
    Citation: BMC Genomics 2009 10:445
  43. Mastitis is the most important disease in dairy cows and it causes significant lost of profit to producers. Identification of the genes, and their variants, involved in innate immune responses is essential for...

    Authors: Karin Alain, Niel A Karrow, Catherine Thibault, Jessika St-Pierre, Martin Lessard and Nathalie Bissonnette
    Citation: BMC Genomics 2009 10:444
  44. MicroRNAs are the major class of gene-regulating molecules playing diverse roles through sequence complementarity to target mRNAs at post-transcriptional level. Tightly regulated expression and interaction of ...

    Authors: Md Munir Hossain, Nasser Ghanem, Michael Hoelker, Franca Rings, Chirawath Phatsara, Ernst Tholen, Karl Schellander and Dawit Tesfaye
    Citation: BMC Genomics 2009 10:443
  45. Diamond-Blackfan anaemia (DBA) is a rare inherited red cell hypoplasia characterised by a defect in the maturation of erythroid progenitors and in some cases associated with malformations. Patients have an inc...

    Authors: Federica Avondo, Paola Roncaglia, Nicoletta Crescenzio, Helena Krmac, Emanuela Garelli, Marta Armiraglio, Carlotta Castagnoli, Maria Francesca Campagnoli, Ugo Ramenghi, Stefano Gustincich, Claudio Santoro and Irma Dianzani
    Citation: BMC Genomics 2009 10:442
  46. Many genes oscillate in their level of expression through the cell division cycle. Previous studies have identified such genes by applying Fourier analysis to cell cycle time course experiments. Typically, suc...

    Authors: Saumyadipta Pyne, Roee Gutman, Chang Sik Kim and Bruce Futcher
    Citation: BMC Genomics 2009 10:440
  47. With the increasing number of expression profiling technologies, researchers today are confronted with choosing the technology that has sufficient power with minimal sample size, in order to reduce cost and ti...

    Authors: M van Iterson, PAC 't Hoen, P Pedotti, GJEJ Hooiveld, JT den Dunnen, GJB van Ommen, JM Boer and RX Menezes
    Citation: BMC Genomics 2009 10:439
  48. Oceans cover more than 70% of the earth's surface and are critical for the homeostasis of the environment. Among the components of the ocean ecosystem, zooplankton play vital roles in energy and matter transfe...

    Authors: Ryuji J Machida, Yasuyuki Hashiguchi, Mutsumi Nishida and Shuhei Nishida
    Citation: BMC Genomics 2009 10:438

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