%PDF-1.3
%
1 0 obj
<>
endobj
2 0 obj
<>stream
Alzheimer’s disease,Genome-wide association study,Quantitative biomarkers,Cognitive traits,Imaging traits
Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
application/pdf
10.1186/s12864-021-08269-8
BMC Genomics
BMC Genomics, 2022, doi:10.1186/s12864-021-08269-8
Alzheimer’s disease
Genome-wide association study
Quantitative biomarkers
Cognitive traits
Imaging traits
Genome-Wide association study of quantitative biomarkers identifies a novel locus for alzheimer’s disease at 12p12.1
Brian Lee
Xiaohui Yao
Li Shen
for the Alzheimer’s Disease Neuroimaging Initiative
2022-01-28T00:44:10+01:00
2022-01-28T00:44:10+01:00
2022-01-28T04:35:46+08:00
LaTeX with hyperref package
uuid:7471156e-8278-49bd-a20b-b36a9a8ce063
uuid:c2c6661c-aa2e-4f00-8f4e-b3bd76083f8c
default
1
converted
uuid:7471156e-8278-49bd-a20b-b36a9a8ce063
converted to PDF/A-2b
pdfToolbox
2022-01-28T07:05:42+08:00
2
B
Springer Nature ORCID Schema
http://springernature.com/ns/xmpExtensions/2.0/
sn
authorInfo
Bag AuthorInformation
external
Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.
editorInfo
Bag EditorInformation
external
Editor information: contains the name of each editor and his/her ORCID identifier.
seriesEditorInfo
Bag SeriesEditorInformation
external
Series editor information: contains the name of each series editor and his/her ORCID identifier.
AuthorInformation
http://springernature.com/ns/xmpExtensions/2.0/authorInfo/
author
Specifies the types of author information: name and ORCID of an author.
name
Text
Gives the name of an author.
orcid
URI
Gives the ORCID of an author.
EditorInformation
http://springernature.com/ns/xmpExtensions/2.0/editorInfo/
editor
Specifies the types of editor information: name and ORCID of an editor.
name
Text
Gives the name of an editor.
orcid
URI
Gives the ORCID of an editor.
SeriesEditorInformation
http://springernature.com/ns/xmpExtensions/2.0/seriesEditorInfo/
seriesEditor
Specifies the types of series editor information: name and ORCID of a series editor.
name
Text
Gives the name of a series editor.
orcid
URI
Gives the ORCID of a series editor.
http://ns.adobe.com/pdf/1.3/
pdf
Adobe PDF Schema
internal
A name object indicating whether the document has been modified to include trapping information
Trapped
Text
http://ns.adobe.com/xap/1.0/mm/
xmpMM
XMP Media Management Schema
internal
UUID based identifier for specific incarnation of a document
InstanceID
URI
internal
The common identifier for all versions and renditions of a document.
OriginalDocumentID
URI
internal
A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original.
DerivedFrom
ResourceRef
Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced.
http://ns.adobe.com/xap/1.0/sType/Part#
stPart
Part
http://ns.adobe.com/xap/1.0/t/pg/
xmpTPg
XMP Paged-Text
internal
A structure containing the characteristics of a font used in a document
Fonts
Bag Font
internal
XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents).
PlateNames
Seq Text
A structure containing the characteristics of a font used in a document.
http://ns.adobe.com/xap/1.0/sType/Font#
stFnt
Font
http://ns.adobe.com/pdfx/1.3/
pdfx
Adobe Document Info PDF eXtension Schema
internal
ID of PDF/X standard
GTS_PDFXVersion
Text
internal
Conformance level of PDF/X standard
GTS_PDFXConformance
Text
internal
Company creating the PDF
Company
Text
internal
Date when document was last modified
SourceModified
Text
http://www.aiim.org/pdfa/ns/id/
pdfaid
PDF/A ID Schema
internal
Part of PDF/A standard
part
Integer
internal
Amendment of PDF/A standard
amd
Text
internal
Conformance level of PDF/A standard
conformance
Text
endstream
endobj
3 0 obj
<>
endobj
5 0 obj
<>/BBox[0 0 11.802 8.41797]/Length 15>>stream
HR(T0 u
endstream
endobj
6 0 obj
<>/ExtGState<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI]/Font<>>>/Annots[20 0 R 21 0 R 22 0 R 23 0 R 24 0 R 25 0 R 26 0 R 27 0 R 28 0 R 29 0 R 30 0 R 31 0 R 32 0 R 33 0 R 34 0 R 35 0 R]/CropBox[0 0 595 791]/Parent 36 0 R/Rotate 0/MediaBox[0 0 595 791]/TrimBox[0 0 595 791]>>
endobj
37 0 obj
<>
endobj
38 0 obj
<>/BBox[0 0 11.802 8.418]/Length 15>>stream
HR(T0 u
endstream
endobj
20 0 obj
<>/Rect[258.885 632.856 270.687 641.283]>>
endobj
40 0 obj
<>
endobj
21 0 obj
<>/Rect[174.654 596.991 186.456 605.418]>>
endobj
41 0 obj
<>
endobj
39 0 obj
<>/BBox[0 0 11.802 8.427]/Length 15>>stream
HR(T0 u
endstream
endobj
22 0 obj
<>/Rect[190.368 596.991 202.17 605.418]>>
endobj
42 0 obj
<>
endobj
23 0 obj
<>/Rect[107.577 262.245 119.379 270.672]>>
endobj
43 0 obj
<>
endobj
24 0 obj
<>/Rect[236.484 178.563 248.286 186.981]>>
endobj
45 0 obj
<>
endobj
25 0 obj
<>/Rect[163.908 142.698 175.71 151.116]>>
endobj
46 0 obj
<>
endobj
47 0 obj
<>/BBox[0 0 11.802 8.41803]/Length 15>>stream
HR(T0 u
endstream
endobj
26 0 obj
<>/Rect[188.874 94.881 200.676 103.299]>>
endobj
49 0 obj
<>
endobj
50 0 obj
<>/BBox[0 0 6.897 8.427]/Length 15>>stream
HR(T0 u
endstream
endobj
27 0 obj
<>/Rect[204.588 94.881 216.39 103.299]>>
endobj
51 0 obj
<>
endobj
28 0 obj
<>/Rect[118.017 82.92 129.819 91.347]>>
endobj
52 0 obj
<>
endobj
29 0 obj
<>/Rect[133.731 82.92 145.533 91.347]>>
endobj
53 0 obj
<>
endobj
30 0 obj
<>/Rect[75.888 70.968 87.69 79.386]>>
endobj
54 0 obj
<>
endobj
31 0 obj
<>/Rect[92.727 70.968 104.529 79.386]>>
endobj
55 0 obj
<>
endobj
32 0 obj
<>/C[0 1 1]/Subtype/Link/F 4/Type/Annot/H/I/Border[0 0 0]/AP<>/Rect[435.168 642.549 539.022 653.658]>>
endobj
57 0 obj
<>
endobj
58 0 obj
<>/BBox[0 0 6.897 8.418]/Length 15>>stream
HR(T0 u
endstream
endobj
33 0 obj
<>/C[0 1 1]/Subtype/Link/F 4/Type/Annot/H/I/Border[0 0 0]/AP<>/Rect[303.174 630.597 362.568 641.706]>>
endobj
60 0 obj
<>
endobj
34 0 obj
<>/Rect[366.282 166.512 373.179 174.939]>>
endobj
63 0 obj
<>
endobj
35 0 obj
<>/Rect[492.507 154.56 499.404 162.987]>>
endobj
64 0 obj
<>
endobj
65 0 obj
<>
endobj
66 0 obj
<>
endobj
67 0 obj
<>/ExtGState<>/ProcSet[/PDF/Text/ImageC/ImageB/ImageI]/Font<>/XObject<>/Properties<>>>/Annots[76 0 R 77 0 R 78 0 R 79 0 R 80 0 R 81 0 R 82 0 R]/CropBox[0 0 595 791]/Parent 36 0 R/Rotate 0/MediaBox[0 0 595 791]/TrimBox[0 0 595 791]>>
endobj
83 0 obj
<>
endobj
76 0 obj
<>/Rect[213.354 217.65 220.251 226.068]>>
endobj
84 0 obj
<>
endobj
77 0 obj
<>/Rect[184.356 119.739 285.186 130.848]>>
endobj
86 0 obj
<>
endobj
87 0 obj
<>/BBox[0 0 72.939 10.9109]/Length 15>>stream
HR(T0 u
endstream
endobj
78 0 obj
<>/Rect[437.454 289.38 444.351 297.798]>>
endobj
88 0 obj
<>
endobj
89 0 obj
<>/BBox[0 0 33.717 11.109]/Length 15>>stream
HR(T0 u
endstream
endobj
79 0 obj
<>/Rect[321.03 193.737 327.927 202.155]>>
endobj
80 0 obj
<>/Rect[378.639 145.911 385.536 154.338]>>
endobj
81 0 obj
<>/Rect[491.931 122.007 498.828 130.425]>>
endobj
90 0 obj
<>
endobj
82 0 obj
<>/Rect[342.144 83.874 442.974 94.983]>>
endobj
36 0 obj
<>
endobj
91 0 obj
<>
endobj
100 0 obj
<>/BBox[0 0 6.89697 8.41801]/Length 15>>stream
HR(T0 u
endstream
endobj
101 0 obj
<>stream
hj0B`${Iga
RJ[v',{L.H{vj`XGs
ϛB=m#$+*KK=^^ >gaÛdJWH5p߆ F]G]@WhHJZ.7~yQB94p<߰L6 ggSpB{ݼ