Table 1 Top regulated genes filtered by expression in skeletal muscle
From: Comparative gene expression profiling between human cultured myotubes and skeletal muscle tissue
Gene ID | Gene Name | Description | FC |
|---|---|---|---|
DOWNREGULATED | Â | Â | |
4151 | MB | myoglobin | -2541 |
761 | CA3 | carbonic anhydrase III, muscle specific | -2391 |
29765 | TMOD4 | tropomodulin 4 (muscle) | -1564 |
4634 | MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | -1529 |
844 | CASQ1 | calsequestrin 1 (fast-twitch, skeletal muscle) | -1496 |
270 | AMPD1 | adenosine monophosphate deaminase 1 (isoform M) | -1320 |
4604 | MYBPC1 | myosin binding protein C, slow type | -1128 |
136371 | ASB10 | ankyrin repeat and SOCS box-containing 10 | -869.2 |
91977 | MYOZ3 | myozenin 3 | -841.6 |
4023 | LPL | lipoprotein lipase | -608.5 |
58529 | MYOZ1 | myozenin 1 | -546.7 |
53405 | CLIC5 | chloride intracellular channel 5 | -504.7 |
6271 | S100A1 | S100 calcium binding protein A1 | -366.4 |
57467 | HHATL | hedgehog acyltransferase-like | -364.5 |
57142 | RTN4 | reticulon 4 | -338.4 |
6123 | RPL3L | ribosomal protein L3-like | -317.8 |
200539 | ANKRD23 | ankyrin repeat domain 23 | -298.1 |
4892 | NRAP | nebulin-related anchoring protein | -294.9 |
123722 | FSD2 | fibronectin type III and SPRY domain containing 2 | -293.3 |
760 | CA2 | carbonic anhydrase II | -290.2 |
5837 | PYGM | phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V) | -277.4 |
84448 | ABLIM2 | actin binding LIM protein family, member 2 | -276.9 |
4618 | MYF6 | myogenic factor 6 (herculin) | -265.7 |
142689 | ASB12 | ankyrin repeat and SOCS box-containing 12 | -228.6 |
339456 | TMEM52 | transmembrane protein 52 | -217.2 |
129446 | XIRP2 | xin actin-binding repeat containing 2 | -216.1 |
26287 | ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) | -200.5 |
712 | C1QA | complement component 1, q subcomponent, A chain | -197.9 |
10840 | ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 | -196.1 |
9452 | ITM2A | integral membrane protein 2A | -178.5 |
5104 | SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -175.8 |
825 | CAPN3 | calpain 3, (p94) | -164.2 |
4653 | MYOC | myocilin, trabecular meshwork inducible glucocorticoid response | -162.9 |
55335 | NIPSNAP3B | nipsnap homolog 3B (C. elegans) | -161.9 |
361 | AQP4 | aquaporin 4 | -160.4 |
4129 | MAOB | monoamine oxidase B | -158.9 |
1375 | CPT1B | carnitine palmitoyltransferase 1B (muscle) | -151.4 |
3743 | KCNA7 | potassium voltage-gated channel, shaker-related subfamily, member 7 | -137.9 |
UPREGULATED | Â | Â | |
57214 | KIAA1199 | KIAA1199 | +1279 |
5806 | PTX3 | pentraxin-related gene, rapidly induced by IL-1 beta | +491.7 |
1026 | CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | +192.8 |
114801 | TMEM200A | transmembrane protein 200A | +184.9 |
2335 | FN1 | fibronectin 1 | +82.93/43.39D |
23362 | PSD3 | pleckstrin and Sec7 domain containing 3 | +82.63 |
124565 | SLC38A10 | solute carrier family 38, member 10 | +68.68 |
7077 | TIMP2 | TIMP metallopeptidase inhibitor 2 | +68.09 |
7153 | TOP2A | topoisomerase (DNA) II alpha 170kDa | +43.58 |
8985 | PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | +43.02 |
6505 | SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | +40.97 |
9663 | LPIN2 | lipin 2 | +40.92 |
54480 | CSGlcAT | chondroitin sulfate glucuronyltransferase | +39.96 |
338773 | TMEM119 | transmembrane protein 119 | +38.12 |
5352 | PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | +36.07/25.77D |
493869 | GPX8 | glutathione peroxidase 8 | +35.9 |
3091 | HIF1A | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | +34.89 |
115908 | CTHRC1 | collagen triple helix repeat containing 1 | +33.74 |
8572 | PDLIM4 | PDZ and LIM domain 4 | +31.9 |
151887 | CCDC80 | coiled-coil domain containing 80 | +31.02/17.06D |
4323 | MMP14 | matrix metallopeptidase 14 (membrane-inserted) | +29.75 |
23114 | NFASC | neurofascin homolog (chicken) | +26.53 |
55165 | CEP55 | centrosomal protein 55kDa | +25.73 |
5270 | SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | +24.59 |
54431 | DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | +24.52 |
6695 | SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | +24.35 |
2629 | GBA | glucosidase, beta; acid (includes glucosylceramidase) | +24.33 |
7421 | VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | +23.83 |
4643 | MYO1E | myosin IE | +23.46 |
166929 | SGMS2 | sphingomyelin synthase 2 | +22.63 |
7058 | THBS2 | thrombospondin 2 | +22.59 |