Figure 6

Changes of H3K4me3 modification on selected gene promoters in DCs and macrophages compared to monocytes. Changes are shown as log2 differences in peak intensities either in DCs or macrophages (MF) compared to monocytes and are presented either as gain (positive values) or loss (negative values) of the modification. The filled gray shapes represent the positions of transcripts. The red and green colors in boxes indicate up- and downregulation compared to the mRNA levels in monocytes. H3K4me3 modification changes of (A) cellular marker genes of monocytes, DCs and macrophages, (B, C) chemokine gene clusters on chromosome chr17:29,606,409-31,457,127 and chr16:55,950,219-56,007,475, respectively, and (D) CD1 cluster on chromosome chr1:156,490,551-156,593,967.