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Table 3 Significantly affected pathways in wild type vs. AmTR comparison through GSEA

From: Transcriptional pathways associated with the slow growth phenotype of transformed Anaplasma marginale

GO Category

Description

Lower tail*

Upper tail*

6412

Translation (PMID:16482227 [ISS] Pfam:PF00573)

0.0044

0.9956

6414

Translational elongation (PMID:16482227 [ISS] Pfam:PF00889)

0.0071

0.9929

15940

Pantothenate biosynthetic process (PMID:12721629 [ISS] TIGR_TIGRFAMS:TIGR00018)

0.0158

0.9842

6434

Seryl-tRNA aminoacylation (PMID:16482227 [ISS] TIGR_TIGRFAMS:TIGR00414)

0.0322

0.9678

15986

ATP synthesis coupled proton transport (PMID:16482227 [ISS] TIGR_TIGRFAMS:TIGR01216)

0.0343

0.966

8654

Phospholipid biosynthetic process (PMID:12721629 [ISS] Swiss-Prot:O31752)

0.0343

0.9657

19363

Pyridine nucleotide biosynthetic process (PMID:16482227 [ISS] TIGR_TIGRFAMS:TIGR00550)

0.0381

0.9619

6265

DNA topological change (PMID:16482227 [ISS] TIGR_TIGRFAMS:TIGR01051)

0.9648

0.0352

6364

rRNA processing (GO_REF:0000012 [ISS] Swiss-Prot:P21513)

0.9673

0.0327

917

Barrier septum formation (PMID:16482227 [ISS] TIGR_TIGRFAMS:TIGR00172)

0.9899

0.0101

9152

Purine ribonucleotide biosynthetic process (PMID:16482227 [ISS] TIGR_TIGRFAMS:TIGR00184)

0.9997

0.0003

  1. *Lower/Upper tail: The different pathways evaluated in through GSEA are shown. Lower and Upper tail values show the mass in the permutation based p-value distribution below or above the value of the test statistic.