Table 1 Genes which were significantly up-regulated at any time point. Numbers indicate fold change at that time point.

immune response

SRV_03329_at

INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5

11.85

82.22

91.04

SRV_01342_at

INTERFERON REGULATORY FACTOR 1

1.94

12.71

12.79

SRV_01343_a_at

INTERFERON REGULATORY FACTOR 1

2.10

16.07

15.63

SRV_13637_a_at

INTERFERON INDUCED TRANSMEMBRANE PROTEIN 3 (1–8 U)

1.75

8.48

10.88

SRV_01199_a_at

CLUSTERIN

1.05

4.35

8.02

SRV_00442_at

SOLUTE CARRIER FAMILY 11 (PROTON-COUPLED DIVALENT METAL ION TRANSPORTERS), MEMBER 1

1.28

6.17

5.38

SRV_01303_a_at

GUANYLATE BINDING PROTEIN 1, INTERFERON-INDUCIBLE, 67 KDA

1.10

2.35

2.49

SRV_02828_at

2'-5'-OLIGOADENYLATE SYNTHETASE 3, 100 KDA

2.47

13.56

9.35

SRV_02072_at

CATHEPSIN S

1.54

5.51

6.43

SRV_02588_a_at

LECTIN, GALACTOSIDE-BINDING, SOLUBLE, 3 BINDING PROTEIN

4.04

26.37

24.40

SRV_02586_at

LECTIN, GALACTOSIDE-BINDING, SOLUBLE, 3 BINDING PROTEIN

3.88

21.30

18.03

response to virus

SRV_03073_at

INTERFERON-INDUCED PROTEIN 44

2.05

9.44

13.16

SRV_01439_a_at

MYXOVIRUS (INFLUENZA VIRUS) RESISTANCE 1, INTERFERON-INDUCIBLE PROTEIN P78 (MOUSE)

3.13

29.23

36.80

SRV_01441_at

MYXOVIRUS (INFLUENZA VIRUS) RESISTANCE 1, INTERFERON-INDUCIBLE PROTEIN P78 (MOUSE)

3.26

28.24

35.84

SRV_04604_s_at

INTERFERON INDUCED WITH HELICASE C DOMAIN 1

6.81

27.34

24.15

SRV_04604_at

INTERFERON INDUCED WITH HELICASE C DOMAIN 1

7.27

25.43

22.62

SRV_04518_at

RIBONUCLEASE L (2',5'-OLIGOISOADENYLATE SYNTHETASE-DEPENDENT)

3.30

7.38

8.66

cell defense response

SRV_00353_at

NEUTROPHIL CYTOSOLIC FACTOR 2 (65 KDA, CHRONIC GRANULOMATOUS DISEASE, AUTOSOMAL 2)

1.05

2.07

1.73

SRV_00264_a_at

MYELOPEROXIDASE

1.60

7.60

4.10

antigen processing and presentation

SRV_05347_at

PROTEASOME (PROSOME, MACROPAIN) SUBUNIT, BETA TYPE, 9 (LARGE MULTIFUNCTIONAL PEPTIDASE 2)

1.27

3.73

4.25

lysosome/endosome

SRV_02581_a_at

LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1

1.23

2.26

2.06

SRV_12596_at

EH-DOMAIN CONTAINING 1

1.22

4.16

3.47

inflammatory response

SRV_10702_at

CYTOCHROME B-245, BETA POLYPEPTIDE (CHRONIC GRANULOMATOUS DISEASE)

1.69

5.58

4.40

SRV_00330_at

CYTOCHROME B-245, BETA POLYPEPTIDE (CHRONIC GRANULOMATOUS DISEASE)

1.59

4.74

3.89

SRV_01877_at

CHEMOKINE (C-X-C MOTIF) RECEPTOR 4

1.29

5.70

8.08

SRV_02292_at

N-myc (and STAT) interactor

1.15

2.29

2.29

SRV_00453_a_at

TRANSFORMING GROWTH FACTOR, BETA 1 (CAMURATI-ENGELMANN DISEASE)

1.12

2.19

2.18

SRV_01617_a_at

PENTRAXIN-RELATED GENE, RAPIDLY INDUCED BY IL-1 BETA

2.83

12.82

17.76

cell cycle

SRV_02067_at

POLO-LIKE KINASE 3 (DROSOPHILA)

0.93

3.82

6.18

SRV_11882_s_at

RAS HOMOLOG GENE FAMILY, MEMBER B

1.18

2.33

2.40

SRV_02051_at

RAS HOMOLOG GENE FAMILY, MEMBER B

1.26

2.15

2.28

SRV_02050_at

RAS HOMOLOG GENE FAMILY, MEMBER B

1.23

2.51

2.55

SRV_00154_at

EXOSTOSES (MULTIPLE) 1

0.90

2.07

1.90

glycolysis

SRV_01520_at

pyruvate kinase, muscle

1.41

4.60

4.22

SRV_01519_a_at

pyruvate kinase, muscle

1.56

5.94

5.48

B_s_at

ALDOLASE A, FRUCTOSE-BISPHOSPHATE

1.22

3.14

2.96

transcription

SRV_01351_at

JUN B PROTO-ONCOGENE

1.76

7.82

7.54

SRV_01336_a_at

INHIBITOR OF DNA BINDING 3, DOMINANT NEGATIVE HELIX-LOOP-HELIX PROTEIN

1.56

3.14

3.57

SRV_02310_at

EUKARYOTIC TRANSLATION TERMINATION FACTOR 1

0.95

2.70

2.45

SRV_03646_at

SPEN HOMOLOG, TRANSCRIPTIONAL REGULATOR (DROSOPHILA)

1.15

2.22

2.30

SRV_02571_at

HAIRY AND ENHANCER OF SPLIT 1, (DROSOPHILA)

1.23

4.52

6.10

complement

SRV_00137_a_at

COMPLEMENT COMPONENT 3

1.80

9.79

13.66

SRV_01145_a_at

COMPLEMENT FACTOR B

3.46

18.33

20.05

apoptosis

SRV_02399_a_at

MATRIX METALLOPEPTIDASE 9 (GELATINASE B, 92 KDA GELATINASE, 92 KDA TYPE IV COLLAGENASE)

2.19

6.79

8.78

SRV_02516_at

HEAT SHOCK 70 KDA PROTEIN 5 (GLUCOSE-REGULATED PROTEIN, 78 KDA)

2.70

10.28

7.60

SRV_04970_a_at

CASPASE RECRUITMENT DOMAIN FAMILY, MEMBER 6

1.35

4.78

4.80

SRV_08154_a_at

HEAT SHOCK 70 KDA PROTEIN 9B (MORTALIN-2)

1.18

3.45

2.71

SRV_04300_a_at

CYTOCHROME C, SOMATIC

1.30

2.80

2.64

SRV_02132_at

EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON 1

1.21

3.56

3.38

SRV_01812_a_at

HEAT SHOCK PROTEIN 90 KDA BETA (GRP94), MEMBER 1

1.31

3.53

3.26

SRV_03753_at

GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE, BETA

1.39

7.34

8.89

SRV_03023_a_at

GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE, GAMMA

1.00

3.73

5.99

metabolic process

SRV_05147_a_at

SYNDECAN BINDING PROTEIN (SYNTENIN)

1.27

4.78

4.42

SRV_00332_a_at

glucose-6-phosphate dehydrogenase

1.32

4.55

3.35

SRV_00292_a_at

PHOSPHOMANNOMUTASE 2

1.14

2.61

2.65

SRV_01737_a_at

UDP-N-ACTEYLGLUCOSAMINE PYROPHOSPHORYLASE 1

1.84

2.18

2.59

SRV_05108_a_at

PHOSPHOSERINE AMINOTRANSFERASE 1

1.12

1.97

2.48

C_s_at

ALDOLASE A, FRUCTOSE-BISPHOSPHATE

1.15

2.42

2.27

A_s_at

ALDOLASE A, FRUCTOSE-BISPHOSPHATE

1.24

3.64

3.39

SRV_00129_a_at

ALDOLASE B, FRUCTOSE-BISPHOSPHATE

1.26

2.30

2.13

SRV_02002_at

CARBOXYLESTERASE 1 (MONOCYTE/MACROPHAGE SERINE ESTERASE 1)

1.28

3.86

2.38

signal transduction

SRV_02657_at

PRE-B-CELL COLONY ENHANCING FACTOR 1

1.61

7.61

7.01

SRV_03054_at

MACROPHAGE RECEPTOR WITH COLLAGENOUS STRUCTURE

2.17

8.20

6.82

SRV_01818_at

THIOREDOXIN

1.19

3.29

3.51

SRV_01313_a_at

GRANULIN

1.45

3.72

3.40

SRV_01462_at

NUCLEAR FACTOR OF KAPPA LIGHT POLYPEPTIDE GENE ENHANCER IN B-CELLS 2 (P49/P100)

1.59

3.67

2.77

SRV_03006_a_at

IQ MOTIF CONTAINING GTPASE ACTIVATING PROTEIN 2

1.23

2.59

2.69

SRV_01480_at

PURINERGIC RECEPTOR P2Y, G-PROTEIN COUPLED, 2

1.47

3.17

2.44

SRV_02894_a_at

CAP, ADENYLATE CYCLASE-ASSOCIATED PROTEIN 1 (YEAST)

1.10

2.09

1.76

SRV_00844_a_at

CHLORIDE INTRACELLULAR CHANNEL 1

1.15

1.95

2.10

membrane

SRV_03227_at

NIDOGEN 2 (OSTEONIDOGEN)

1.42

3.69

4.29

SRV_01179_a_at

CD63 ANTIGEN (MELANOMA 1 ANTIGEN)

1.34

3.82

3.97

SRV_02687_s_at

MANNOSE-6-PHOSPHATE RECEPTOR BINDING PROTEIN 1

1.30

4.82

3.55

SRV_04888_a_at

UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 5

2.41

4.44

3.50

SRV_04819_a_at

TRANSMEMBRANE PROTEIN 49

1.46

3.40

3.20

SRV_04070_a_at

LEUCINE RICH REPEAT CONTAINING 59

1.22

2.48

2.78

SRV_03407_at

FER-1-LIKE 3, MYOFERLIN (C. ELEGANS)

1.22

2.67

3.81

SRV_05439_at

HYPOTHETICAL PROTEIN LOC441168

1.40

3.43

2.79

SRV_02874_a_at

BRAIN ABUNDANT, MEMBRANE ATTACHED SIGNAL PROTEIN 1

1.33

2.80

2.31

SRV_04226_a_at

GTPASE, IMAP FAMILY MEMBER 5

1.13

2.05

2.02

transport

SRV_00744_a_at

ADIPOSE DIFFERENTIATION-RELATED PROTEIN

3.49

12.49

7.34

SRV_00294_s_at

PROTECTIVE PROTEIN FOR BETA-GALACTOSIDASE (GALACTOSIALIDOSIS)

1.53

5.23

4.73

SRV_02592_a_at

LYSYL OXIDASE-LIKE 1

1.18

2.81

4.59

SRV_03991_a_at

SOLUTE CARRIER FAMILY 15, MEMBER 3

1.36

5.33

3.88

SRV_03562_at

ERO1-LIKE (S. CEREVISIAE)

1.00

2.24

1.77

SRV_04996_at

SOLUTE CARRIER FAMILY 7 (CATIONIC AMINO ACID TRANSPORTER, Y+ SYSTEM), MEMBER 3

1.07

1.75

2.11

SRV_01134_at

ATPASE, H+ TRANSPORTING, LYSOSOMAL 56/58 KDA, V1 SUBUNIT B2

1.04

2.17

1.59

SRV_01220_at

CYTOCHROME C OXIDASE SUBUNIT VIB POLYPEPTIDE 1 (UBIQUITOUS)

1.15

4.51

4.18

SRV_02133_a_at

GOLGI SNAP RECEPTOR COMPLEX MEMBER 2

1.05

2.24

1.88

extracellular region

SRV_02948_a_at

fibulin 1

0.93

1.65

2.24

SRV_01275_at

fibulin 1

0.81

1.54

2.10

SRV_02965_at

TISSUE FACTOR PATHWAY INHIBITOR 2

3.56

3.04

2.56

SRV_03142_at

ELASTIN MICROFIBRIL INTERFACER 1

1.11

3.37

3.73

ion binding

SRV_00713_a_at

TRANSCOBALAMIN I (VITAMIN B12 BINDING PROTEIN, R BINDER FAMILY)

2.55

23.02

12.98

SRV_02456_at

GASTRIC INTRINSIC FACTOR (VITAMIN B SYNTHESIS)

3.36

20.67

11.63

SRV_07722_at

CHROMOSOME 17 OPEN READING FRAME 27

0.94

4.46

4.63

SRV_05460_at

tripartite motif-containing 39

1.58

3.81

4.07

SRV_05065_at

tripartite motif-containing 17

1.53

2.86

3.46

SRV_00371_a_at

FRUCTOSE-1,6-BISPHOSPHATASE 1

2.40

5.01

3.14

SRV_00741_a_at

ADENOSINE DEAMINASE, RNA-SPECIFIC

1.44

3.76

2.86

SRV_00562_a_at

PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 1 (PROSTAGLANDIN G/H SYNTHASE AND CYCLOOXYGENASE)

1.29

2.05

2.54

SRV_05448_at

ATPase, Ca++ transporting, cardiac muscle, slow twitch 2

0.87

2.16

2.13

SRV_02724_at

METHIONINE ADENOSYLTRANSFERASE II, ALPHA

1.66

2.06

1.56

SRV_00449_a_at

LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN 1

1.05

1.79

3.15

SRV_00131_a_at

SECRETED PROTEIN, ACIDIC, CYSTEINE-RICH (OSTEONECTIN)

1.19

1.99

2.74

SRV_04896_a_at

TRANSKETOLASE (WERNICKE-KORSAKOFF SYNDROME)

1.44

4.02

2.52

SRV_02047_at

ANNEXIN A2

1.29

2.15

2.45

SRV_01345_at

INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR, TYPE 3

1.19

2.80

2.35

SRV_12418_at

MYOSIN, LIGHT POLYPEPTIDE 9, REGULATORY

1.01

1.99

2.20

SRV_01649_at

RETICULOCALBIN 1, EF-HAND CALCIUM BINDING DOMAIN

1.16

3.01

2.68

Protein binding/transport

SRV_03206_at

V-SET AND IMMUNOGLOBULIN DOMAIN CONTAINING 4

1.90

13.14

9.17

SRV_00797_a_at

SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), MEMBER 1, (COLLAGEN BINDING PROTEIN 1)

1.77

4.67

4.79

SRV_04964_a_at

TUBULIN, BETA 6

1.06

2.53

2.55

SRV_03477_a_at

TRANSMEMBRANE PROTEIN 4

1.59

2.22

2.39

SRV_02085_at

FK506 BINDING PROTEIN 1B, 12.6 KDA

1.29

1.71

2.18

SRV_02652_a_at

PROTEIN DISULFIDE ISOMERASE FAMILY A, MEMBER 6

1.28

2.16

1.99

SRV_02814_at

DNAJ (HSP40) HOMOLOG, SUBFAMILY B, MEMBER 1

2.35

4.29

1.73

SRV_03255_a_at

AHA1, ACTIVATOR OF HEAT SHOCK 90 KDA PROTEIN ATPASE HOMOLOG 1 (YEAST)

1.07

2.14

1.53

SRV_05534_at

HYPOTHETICAL PROTEIN MGC16212

1.74

4.05

3.73

SRV_00840_a_at

COLD INDUCIBLE RNA BINDING PROTEIN

1.03

2.46

3.20

SRV_01147_a_at

BIGLYCAN

0.99

2.01

2.90

SRV_05461_x_at

tripartite motif-containing 39

1.32

2.53

2.76

SRV_02070_a_at

CYSTEINE AND GLYCINE-RICH PROTEIN 1

1.27

2.22

2.46

SRV_00257_at

KERATIN 18

1.12

1.93

2.44

SRV_04005_at

KDEL (LYS-ASP-GLU-LEU) ENDOPLASMIC RETICULUM PROTEIN RETENTION RECEPTOR 3

0.90

2.07

2.06

SRV_02647_a_at

ARP2 ACTIN-RELATED PROTEIN 2 HOMOLOG (YEAST)

1.23

2.33

1.93

SRV_01234_a_at

CATENIN (CADHERIN-ASSOCIATED PROTEIN), ALPHA 1, 102 KDA

0.98

1.43

2.05

SRV_01504_a_at

PHOSPHOGLUCONATE DEHYDROGENASE

1.19

2.20

1.50

SRV_05174_a_at

THREE PRIME REPAIR EXONUCLEASE 2

1.57

5.55

5.02

protein modification

SRV_04305_a_at

GLYCINE N-METHYLTRANSFERASE

1.24

1.84

3.49

SRV_01832_a_at

UBIQUITIN-CONJUGATING ENZYME E2L 3

1.04

2.09

1.99

SRV_00309_at

TRANSGLUTAMINASE 1 (K POLYPEPTIDE EPIDERMAL TYPE I, PROTEIN-GLUTAMINE-GAMMA-GLUTAMYLTRANSFERASE)

3.22

16.60

14.36

SRV_02093_a_at

HEAT SHOCK 70 KDA PROTEIN 9B (MORTALIN-2)

1.35

3.91

2.79

SRV_02989_at

HEAT SHOCK 70 KDA PROTEIN 8

2.28

6.93

2.73

SRV_01225_at

CRYSTALLIN, ALPHA B

1.27

3.35

2.38

SRV_05456_a_at

UBIQUITIN SPECIFIC PEPTIDASE 2

1.27

2.56

2.00

SRV_05457_a_at

UBIQUITIN SPECIFIC PEPTIDASE 2

1.26

2.28

1.89

SRV_11417_a_at

MATRIX METALLOPEPTIDASE 1 (INTERSTITIAL COLLAGENASE)

5.26

13.96

3.65

SRV_04306_at

GLYCINE N-METHYLTRANSFERASE

1.03

2.15

4.66

SRV_00327_a_at

CATHEPSIN K (PYCNODYSOSTOSIS)

1.37

3.23

3.94

cellular process

SRV_11663_a_at

TIMP METALLOPEPTIDASE INHIBITOR 1

1.96

24.74

23.31

SRV_04387_at

RETINOIC ACID RECEPTOR RESPONDER (TAZAROTENE INDUCED) 1

1.64

6.63

9.22

SRV_03285_at

RELATED RAS VIRAL (R-RAS) ONCOGENE HOMOLOG 2

1.76

5.07

4.97

SRV_04911_at

SIMILAR TO THIOREDOXIN DOMAIN-CONTAINING 2

1.34

3.15

3.20

SRV_01534_at

PROTEIN PHOSPHATASE 1, CATALYTIC SUBUNIT, ALPHA ISOFORM

1.15

2.04

2.18

SRV_04858_at

POLY (ADP-RIBOSE) POLYMERASE FAMILY, MEMBER 9

0.97

2.36

2.15

SRV_03421_a_at

LR8 PROTEIN

1.31

1.95

2.02

SRV_11406_at

V-YES-1 YAMAGUCHI SARCOMA VIRAL RELATED ONCOGENE HOMOLOG

1.37

2.46

2.12

other

SRV_03887_at

DYNEIN, CYTOPLASMIC 1, LIGHT INTERMEDIATE CHAIN 1

1.31

2.42

2.20

SRV_01920_at

poly (ADP-ribose) glycohydrolase

1.31

1.95

2.23

SRV_00155_a_at

COAGULATION FACTOR XIII, A1 POLYPEPTIDE

1.20

2.46

2.35

SRV_01367_a_at

KERATIN 8

1.19

2.90

3.29

SRV_00775_at

ARGINASE, TYPE II

1.44

4.08

6.06

SRV_11767_a_at

INTERFERON INDUCED TRANSMEMBRANE PROTEIN 5

1.17

2.74

4.24

SRV_07726_a_at

MACROPHAGE EXPRESSED GENE 1

1.69

4.25

3.18

SRV_01302_at

GUANYLATE BINDING PROTEIN 4

1.07

2.39

2.64

SRV_02761_at

ARGININE-RICH, MUTATED IN EARLY STAGE TUMORS

1.10

2.17

1.99

SRV_03758_a_at

ARRESTIN DOMAIN CONTAINING 2

0.90

5.48

8.72