Transcriptional response of Mexican axolotls to Ambystoma tigrinum virus (ATV) infection

BMC Genomics

Table 3 Significant (p ≤ 0.05 geometric mean p-value) functional groups obtained from functional annotation using DAVID.

	Ontology	Number of Genes	p-value		Ontology	Number of Genes	p-value
Functional Group 1	response to biotic stimulus	25	<0.001	Functional Group 5	water-soluble vitamin metabolism	4	0.02
<0.001	immune response	21	<0.001	0.033	vitamin metabolism	4	0.03
	defense response	22	<0.001		pyridine nucleotide metabolism	3	0.07
Functional Group 2	cation binding	34	0.001	Functional Group 6	di-, tri-valent inorganic cation transport	5	0.006
0.002	ion binding	36	0.004	0.042	metal ion transport	5	0.06
	metal ion binding	36	0.004		cation transport	6	0.22
Functional Group 3	innate immunity	4	0.001	Functional Group 7	bcr protein	3	0.02
0.005	immune response	5	0.004	0.045	molecular chaperone	4	0.02
	innate immune response	4	0.007		Heat shock protein Hsp70	3	0.03
	complement activation	3	0.02		Heat shock protein 70	3	0.03
					antigen processing and presentation	4	0.09
					cell surface	3	0.20
Functional Group 4	lysosome	7	0.002
0.008	lysosome	7	0.009	Functional Group 8	response to unfolded protein	5	0.02
	lytic vacuole	7	0.009	0.048	response to protein stimulus	5	0.02
	vacuole	7	0.02		chaperone	6	0.26

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