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An in-depth analysis of the genomes of the Q fever-causing bacterium Coxiella burnetii shows an evolutionary pattern based on the modification of existing genes, supporting a model of clonal expansion of established genotypes, with significant variation at protein level.
Methylation levels of N6-adenine (6mA) and N4-cytosine (4mC) observed in metazoan samples may be due to bacterial contamination or incorporation of methylated nucleosides from exogenous DNA.
Aims and scope
- Matteo Pasini, BioMed Central, UK
- Alexandria Latto, BioMed Central, UK
- Arwa Tawfiq, BioMed Central, UK
- Shane C Burgess, University of Arizona
- Leonid Bystrykh, University of Groningen
- Alexei Fedorov, University of Toledo
- Scott E Hemby, Wake Forest University
- David Lightfoot, Southern Illinois University at Carbondale
- Leonard Schalkwyk, King's College London
- Jacqueline Smith, The Roslin Institute
- Theo Smits, Zürich University for Applied Sciences
- Stefan Wiemann, German Cancer Research Center
Dr. Jacqueline Smith is a Career Track Fellow at The Roslin Institute in Edinburgh. She joined the Editorial Board of BMC Genomics in 2015.
BMC Series blog
19 September 2019
13 September 2019
09 September 2019