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  1. Content type: Research

    The advances in target control of complex networks not only can offer new insights into the general control dynamics of complex systems, but also be useful for the practical application in systems biology, suc...

    Authors: Wei-Feng Guo, Shao-Wu Zhang, Qian-Qian Shi, Cheng-Ming Zhang, Tao Zeng and Luonan Chen

    Citation: BMC Genomics 2018 19(Suppl 1):924

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  2. Content type: Research

    Since the establishment of the first biomedical ontology Gene Ontology (GO), the number of biomedical ontology has increased dramatically. Nowadays over 300 ontologies have been built including extensively use...

    Authors: Liang Cheng, Yue Jiang, Hong Ju, Jie Sun, Jiajie Peng, Meng Zhou and Yang Hu

    Citation: BMC Genomics 2018 19(Suppl 1):919

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  3. Content type: Research

    Ebolavirus (EBOV) is responsible for one of the most fatal diseases encountered by mankind. Cellular T-cell responses have been implicated to be important in providing protection against the virus. Antigenic vari...

    Authors: Wan Ching Lim and Asif M. Khan

    Citation: BMC Genomics 2018 19(Suppl 1):42

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  4. Content type: Research

    Recent results demonstrated that either non-coding or coding genes generate phased secondary small interfering RNAs (phasiRNAs) guided by specific miRNAs. Till now, there is no studies for phasiRNAs in Panax noto...

    Authors: Kun Chen, Li Liu, Xiaotuo Zhang, Yuanyuan Yuan, Shuchao Ren, Junqiang Guo, Qingyi Wang, Peiran Liao, Shipeng Li, Xiuming Cui, Yong-Fang Li and Yun Zheng

    Citation: BMC Genomics 2018 19(Suppl 1):41

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  5. Content type: Research article

    The immunoglobulin (Ig) superfamily receptor Down syndrome cell adhesion molecule (Dscam) gene can generate tens of thousands of isoforms via alternative splicing, which is essential for both nervous and immune s...

    Authors: Guozheng Cao, Yang Shi, Jian Zhang, Hongru Ma, Shouqing Hou, Haiyang Dong, Weiling Hong, Shuo Chen, Hao Li, Yandan Wu, Pengjuan Guo, Xu Shao, Bingbing Xu, Feng Shi, Yijun Meng and Yongfeng Jin

    Citation: BMC Genomics 2018 19:66

    Published on:

  6. Content type: Research

    Transcriptional target genes show functional enrichment of genes. However, how many and how significantly transcriptional target genes include functional enrichments are still unclear. To address these issues,...

    Authors: Naoki Osato

    Citation: BMC Genomics 2018 19(Suppl 1):957

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  7. Content type: Research

    Adenosine-to-Inosine (A-to-I) RNA editing is catalyzed by the adenosine deaminase acting on RNA (ADAR) family of enzymes, which induces alterations in mRNA sequence. It has been shown that A-to-I RNA editing e...

    Authors: Yaowei Huang, Yingying Cao, Jiarui Li, Yuanhua Liu, Wu Zhong, Xuan Li, Chen Chen and Pei Hao

    Citation: BMC Genomics 2018 19(Suppl 1):43

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  8. Content type: Research

    Post-translational modification is considered an important biological mechanism with critical impact on the diversification of the proteome. Although a long list of such modifications has been studied, succiny...

    Authors: Yosvany López, Alok Sharma, Abdollah Dehzangi, Sunil Pranit Lal, Ghazaleh Taherzadeh, Abdul Sattar and Tatsuhiko Tsunoda

    Citation: BMC Genomics 2018 19(Suppl 1):923

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  9. Content type: Research article

    Infectious disease is the single greatest threat to taxa such as amphibians (chytrid fungus), bats (white nose syndrome), Tasmanian devils (devil facial tumor disease), and black-footed ferrets (canine distemp...

    Authors: Jean P. Elbers, Mary B. Brown and Sabrina S. Taylor

    Citation: BMC Genomics 2018 19:64

    Published on:

  10. Content type: Research

    RNA editing is an important mechanism that expands the diversity and complexity of genetic codes. The conversions of adenosine (A) to inosine (I) and cytosine (C) to uridine (U) are two prominent types of RNA ...

    Authors: Yingying Cao, Ruiyuan Cao, Yaowei Huang, Hongxia Zhou, Yuanhua Liu, Xuan Li, Wu Zhong and Pei Hao

    Citation: BMC Genomics 2018 19(Suppl 1):925

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  11. Content type: Research

    Whole-genome sequencing (WGS) plays an increasingly important role in clinical practice and public health. Due to the big data size, WGS data analysis is usually compute-intensive and IO-intensive. Currently i...

    Authors: Yiqi Wang, Gen Li, Mark Ma, Fazhong He, Zhuo Song, Wei Zhang and Chengkun Wu

    Citation: BMC Genomics 2018 19(Suppl 1):959

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  12. Content type: Research

    Emerging evidence has been experimentally confirmed the tissue-specific expression of circRNAs (circRNAs). Global identification of human tissue-specific circRNAs is crucial for the functionality study, which ...

    Authors: Yu-Chen Liu, Yu-Jung Chiu, Jian-Rong Li, Chuan-Hu Sun, Chun-Chi Liu and Hsien-Da Huang

    Citation: BMC Genomics 2018 19(Suppl 1):958

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  13. Content type: Research

    Since PGAP (pan-genome analysis pipeline) was published in 2012, it has been widely employed in bacterial genomics research. Though PGAP has integrated several modules for pan-genomics analysis, how to properl...

    Authors: Yongbing Zhao, Chen Sun, Dongyu Zhao, Yadong Zhang, Yang You, Xinmiao Jia, Junhui Yang, Lingping Wang, Jinyue Wang, Haohuan Fu, Yu Kang, Fei Chen, Jun Yu, Jiayan Wu and Jingfa Xiao

    Citation: BMC Genomics 2018 19(Suppl 1):36

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  14. Content type: Research

    It has been observed that many transcription factors (TFs) can bind to different genomic loci depending on the cell type in which a TF is expressed in, even though the individual TF usually binds to the same c...

    Authors: Xin Wang, Peijie Lin and Joshua W. K. Ho

    Citation: BMC Genomics 2018 19(Suppl 1):929

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  15. Content type: Research

    Natural rubber is an economically important material. Currently the Pará rubber tree, Hevea brasiliensis is the main commercial source. Little is known about rubber biosynthesis at the molecular level. Next-gener...

    Authors: Yuko Makita, Mika Kawashima, Nyok Sean Lau, Ahmad Sofiman Othman and Minami Matsui

    Citation: BMC Genomics 2018 19(Suppl 1):922

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  16. Content type: Introduction

    The 16th International Conference on Bioinformatics (InCoB) was held at Tsinghua University, Shenzhen from September 20 to 22, 2017. The annual conference of the Asia-Pacific Bioinformatics Network featured si...

    Authors: Christian Schönbach, Jinyan Li, Lan Ma, Paul Horton, Muhammad Farhan Sjaugi and Shoba Ranganathan

    Citation: BMC Genomics 2018 19(Suppl 1):920

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  17. Content type: Research

    Inferring phylogenetic trees for newly recovered genomes from metagenomic samples is very useful in determining the identities of uncultivated microorganisms. Even though 16S ribosomal RNA small subunit genes ...

    Authors: Yu-Wei Wu

    Citation: BMC Genomics 2018 19(Suppl 1):921

    Published on:

    This article is part of a Supplement: Volume 19 Supplement 1

  18. Content type: Database

    Euplotes, a ciliated protozoan, is a useful unicellular model organism. Studies on Euplotes have provided excellent insights into various basic biological principles. We have recently sequenced the macronuclear g...

    Authors: Ruan-lin Wang, Wei Miao, Wei Wang, Jie Xiong and Ai-hua Liang

    Citation: BMC Genomics 2018 19:63

    Published on:

  19. Content type: Research article

    Heat shock proteins (Hsps) are essential components in plant tolerance mechanism under various abiotic stresses. Hsp20 is the major family of heat shock proteins, but little of Hsp20 family is known in potato (So...

    Authors: Peng Zhao, Dongdong Wang, Ruoqiu Wang, Nana Kong, Chao Zhang, Chenghui Yang, Wentao Wu, Haoli Ma and Qin Chen

    Citation: BMC Genomics 2018 19:61

    Published on:

  20. Content type: Research article

    The neural crest (NC) is a class of transitory stem cell-like cells unique to vertebrate embryos. NC cells arise within the dorsal neural tube where they undergo an epithelial to mesenchymal transition in orde...

    Authors: Nicole J. Ward, Darrell Green, Janet Higgins, Tamas Dalmay, Andrea Münsterberg, Simon Moxon and Grant N. Wheeler

    Citation: BMC Genomics 2018 19:59

    Published on:

  21. Content type: Research article

    De novo heterozygous assembly is an ongoing challenge requiring improved assembly approaches. In this study, three strategies were used to develop de novo Vitis vinifera ‘Sultanina’ genome assemblies for comparis...

    Authors: Sagar Patel, Zhixiu Lu, Xiaozhu Jin, Padmapriya Swaminathan, Erliang Zeng and Anne Y. Fennell

    Citation: BMC Genomics 2018 19:57

    Published on:

  22. Content type: Research article

    The Ceratocystis genus harbors a large number of phytopathogenic fungi that cause xylem parenchyma degradation and vascular destruction on a broad range of economically important plants. Ceratocystis cacaofunesta

    Authors: Eddy Patricia Lopez Molano, Odalys García Cabrera, Juliana Jose, Leandro Costa do Nascimento, Marcelo Falsarella Carazzolle, Paulo José Pereira Lima Teixeira, Javier Correa Alvarez, Ricardo Augusto Tiburcio, Paulo Massanari Tokimatu Filho, Gustavo Machado Alvares de Lima, Rafael Victório Carvalho Guido, Thamy Lívia Ribeiro Corrêa, Adriana Franco Paes Leme, Piotr Mieczkowski and Gonçalo Amarante Guimarães Pereira

    Citation: BMC Genomics 2018 19:58

    Published on:

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