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  1. Histone deacetylases (HDACs) catalyze histone deacetylation and suppress gene transcription during various cellular processes. Within the superfamily of HDACs, RPD3/HDA1-type HDACs are the most studied, and it is...

    Authors: Jingjing Zhang, Aimin Wu, Hengling Wei, Pengbo Hao, Qi Zhang, Miaomiao Tian, Xu Yang, Shuaishuai Cheng, Xiaokang Fu, Liang Ma, Hantao Wang and Shuxun Yu

    Citation: BMC Genomics 2020 21:643

    Content type: Research article

    Published on:

  2. The Pacific bluefin tuna (Thunnus orientalis) is a regionally endothermic fish that maintains temperatures in their swimming musculature, eyes, brain and viscera above that of the ambient water. Within their skel...

    Authors: Adam Ciezarek, Luke Gardner, Vincent Savolainen and Barbara Block

    Citation: BMC Genomics 2020 21:642

    Content type: Research article

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  3. Parkinson’s disease (PD) is a degenerative disease with early-stage pathology hypothesized to manifest in brainstem regions. Vocal deficits, including soft, monotone speech, result in significant clinical and ...

    Authors: Cynthia A. Kelm-Nelson and Stephen Gammie

    Citation: BMC Genomics 2020 21:625

    Content type: Research article

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  4. In 2014, a novel tick-borne virus of the Flaviviridae family was first reported in the Mogiana region of Brazil and named the Mogiana tick virus (MGTV). Thereafter, the Jingmen tick virus (JMTV), Kindia tick viru...

    Authors: Xiaofeng Xu, Jinlong Bei, Yibo Xuan, Jiayuan Chen, Defu Chen, Stephen C. Barker, Samuel Kelava, Xiaoai Zhang, Shan Gao and Ze Chen

    Citation: BMC Genomics 2020 21:641

    Content type: Research article

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  5. Marine medaka (Oryzias melastigma) is considered as an important ecotoxicological indicator to study the biochemical, physiological and molecular responses of marine organisms towards increasing amount of polluta...

    Authors: Pingping Liang, Hafiz Sohaib Ahmed Saqib, Xiaomin Ni and Yingjia Shen

    Citation: BMC Genomics 2020 21:640

    Content type: Research article

    Published on:

  6. Entada phaseoloides (L.) Merr. is an important traditional medicinal plant. The stem of Entada phaseoloides is popularly used as traditional medicine because of its significance in dispelling wind and dampness an...

    Authors: Weifang Liao, Zhinan Mei, Lihong Miao, Pulin Liu and Ruijie Gao

    Citation: BMC Genomics 2020 21:639

    Content type: Research article

    Published on:

  7. Plant viruses maintain intricate interactions with their vector and non-vector insects and can impact the fitness of insects. However, the details of their molecular and cellular mechanisms have not been studi...

    Authors: Dandan Li, Chi Zhang, Zeqian Tong, Dan Su, Gaisheng Zhang, Shize Zhang, Huiyan Zhao and Zuqing Hu

    Citation: BMC Genomics 2020 21:638

    Content type: Research article

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  8. Transcriptome sequencing has opened the field of genomics to a wide variety of researchers, owing to its efficiency, applicability across species and ability to quantify gene expression. The resulting datasets...

    Authors: Cameron J. Hyde, Quinn P. Fitzgibbon, Abigail Elizur, Gregory G. Smith and Tomer Ventura

    Citation: BMC Genomics 2020 21:637

    Content type: Database

    Published on:

  9. Improving sow fertility is extremely important as it can lead to increased reproductive efficiency and thus profitability for swine producers. There are considerable differences in fertility rates among indivi...

    Authors: Huiyan Hu, Qing Jia, Jianzhong Xi, Bo Zhou and Zhiqiang Li

    Citation: BMC Genomics 2020 21:636

    Content type: Research article

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  10. Protein kinases (PKs) play an important role in signaling cascades and are one of the largest and most conserved protein super families in plants. Despite their importance, the woodland strawberry (Fragaria vesca

    Authors: Hui Liu, Wei Qu, Kaikai Zhu and Zong-Ming ( Max) Cheng

    Citation: BMC Genomics 2020 21:635

    Content type: Research article

    Published on:

  11. Chilo suppressalis is a widespread rice pest that poses a major threat to food security in China. This pest can develop resistance to Cry toxins from Bacillus thuringiensis (Bt), threatening the sustainable use o...

    Authors: Geng Chen, Yanhui Wang, Yanmin Liu, Fajun Chen and Lanzhi Han

    Citation: BMC Genomics 2020 21:634

    Content type: Research article

    Published on:

  12. Previous studies show that galanin neurons in ventrolateral preoptic nucleus (VLPO-Gal) are essential for sleep regulation. Here, we explored the transcriptional regulation of the VLPO-Gal neurons in sleep by ...

    Authors: Xiaofeng Guo, Xiaoling Gao, Brendan T. Keenan, Jingxu Zhu, Dimitra Sarantopoulou, Jie Lian, Raymond J. Galante, Gregory R. Grant and Allan I. Pack

    Citation: BMC Genomics 2020 21:633

    Content type: Research article

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  13. Functional genomics employs several experimental approaches to investigate gene functions. High-throughput techniques, such as loss-of-function screening and transcriptome profiling, allow to identify lists of...

    Authors: Natalia Rubanova, Guillaume Pinna, Jeremie Kropp, Anna Campalans, Juan Pablo Radicella, Anna Polesskaya, Annick Harel-Bellan and Nadya Morozova

    Citation: BMC Genomics 2020 21:632

    Content type: Methodology article

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  14. We benchmarked the hybrid assembly approaches of MaSuRCA, SPAdes, and Unicycler for bacterial pathogens using Illumina and Oxford Nanopore sequencing by determining genome completeness and accuracy, antimicrob...

    Authors: Zhao Chen, David L. Erickson and Jianghong Meng

    Citation: BMC Genomics 2020 21:631

    Content type: Research article

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  15. The contribution of mitogen-activated protein kinase (MAPK) cascades to plant growth and development has been widely studied, but this knowledge has not yet been extended to the medicinal plant Salvia miltiorrhiz...

    Authors: Yongfeng Xie, Meiling Ding, Bin Zhang, Jie Yang, Tianlin Pei, Pengda Ma and Juane Dong

    Citation: BMC Genomics 2020 21:630

    Content type: Research article

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  16. Seasonal weight loss (SWL) is a very important limitation to the production of ruminants in the Mediterranean and Tropical regions. In these areas, long dry seasons lead to poor pastures with low nutritional v...

    Authors: José Ricardo Parreira, Lorenzo Enrique Hernández-Castellano, Anastasio Argüello, Juan Capote, Noemí Castro, Susana de Sousa Araújo and André Martinho de Almeida

    Citation: BMC Genomics 2020 21:629

    Content type: Research article

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  17. Age-related resistance (ARR) is a developmentally regulated phenomenon conferring resistance to pathogens or pests. Although ARR has been observed in several host-pathogen systems, the underlying mechanisms ar...

    Authors: Ben N. Mansfeld, Marivi Colle, Chunqiu Zhang, Ying-Chen Lin and Rebecca Grumet

    Citation: BMC Genomics 2020 21:628

    Content type: Research article

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  18. DNA N4-methylcytosine (4mC) is a critical epigenetic modification and has various roles in the restriction-modification system. Due to the high cost of experimental laboratory detection, computational methods ...

    Authors: Zhixun Zhao, Xiaocai Zhang, Fang Chen, Liang Fang and Jinyan Li

    Citation: BMC Genomics 2020 21:627

    Content type: Research article

    Published on:

  19. The environmental impact of pig farming need to be reduced, with phosphorus (P) being of particular interest. Specified dietary regimens and management systems contribute to meet environmental concerns and red...

    Authors: Aisanjiang Wubuli, Christian Gerlinger, Henry Reyer, Michael Oster, Eduard Muráni, Nares Trakooljul, Siriluck Ponsuksili, Petra Wolf and Klaus Wimmers

    Citation: BMC Genomics 2020 21:626

    Content type: Research article

    Published on:

  20. The cattle introduced by European conquerors during the Brazilian colonization period were exposed to a process of natural selection in different types of biomes throughout the country, leading to the developm...

    Authors: Elisa Peripolli, Christian Reimer, Ngoc-Thuy Ha, Johannes Geibel, Marco Antonio Machado, João Cláudio do Carmo Panetto, Andréa Alves do Egito, Fernando Baldi, Henner Simianer and Marcos Vinícius Gualberto Barbosa da Silva

    Citation: BMC Genomics 2020 21:624

    Content type: Research article

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  21. Goats (Capra hircus), one of the first domesticated species, are economically important for milk and meat production, and their broad geographical distribution reflects their successful adaptation to diverse envi...

    Authors: Francesco Giannico, Serafina Massari, Anna Caputi Jambrenghi, Adriano Soriano, Angela Pala, Giovanna Linguiti, Salvatrice Ciccarese and Rachele Antonacci

    Citation: BMC Genomics 2020 21:623

    Content type: Research article

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  22. Peromyscus are the most common mammalian species in North America and are widely used in both laboratory and field studies. The deer mouse, P. maniculatus and the old-field mouse, P. polionotus, are closely relat...

    Authors: Zhenhua Shang, David J. Horovitz, Ronald H. McKenzie, Jessica L. Keisler, Michael R. Felder and Shannon W. Davis

    Citation: BMC Genomics 2020 21:622

    Content type: Research article

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  23. Chrysosplenium L. (Saxifragaceae) is a genus of plants widely distributed in Northern Hemisphere and usually found in moist, shaded valleys and mountain slopes. This genus is ideal for studying plant adaptation t...

    Authors: Zhihua Wu, Rui Liao, Tiange Yang, Xiang Dong, Deqing Lan, Rui Qin and Hong Liu

    Citation: BMC Genomics 2020 21:621

    Content type: Research article

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  24. Since 2008, the aquaculture production of Crassostrea gigas was heavily affected by mass mortalities associated to Ostreid herpesvirus 1 (OsHV-1) microvariants worldwide. Transcriptomic studies revealed the major...

    Authors: Umberto Rosani, Miriam Abbadi, Timothy Green, Chang-Ming Bai, Edoardo Turolla, Giuseppe Arcangeli, K. Mathias Wegner and Paola Venier

    Citation: BMC Genomics 2020 21:620

    Content type: Research article

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  25. Chimpanzees are the closest living relatives of humans. The divergence between human and chimpanzee ancestors dates to approximately 6,5–7,5 million years ago. Genetic features distinguishing us from chimpanze...

    Authors: Maria V. Suntsova and Anton A. Buzdin

    Citation: BMC Genomics 2020 21(Suppl 7):535

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  26. Massive forest decline has been observed almost everywhere as a result of negative anthropogenic and climatic effects, which can interact with pests, fungi and other phytopathogens and aggravate their effects....

    Authors: Vasilina S. Akulova, Vadim V. Sharov, Anastasiya I. Aksyonova, Yuliya A. Putintseva, Natalya V. Oreshkova, Sergey I. Feranchuk, Dmitry A. Kuzmin, Igor N. Pavlov, Yulia A. Litovka and Konstantin V. Krutovsky

    Citation: BMC Genomics 2020 21(Suppl 7):534

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  27. Head-to-head comparison of BeadChip and WGS/WES genotyping techniques for their precision is far from straightforward. A tool for validation of high-throughput genotyping calls such as Sanger sequencing is nei...

    Authors: Kirill A. Danilov, Dimitri A. Nikogosov, Sergey V. Musienko and Ancha V. Baranova

    Citation: BMC Genomics 2020 21(Suppl 7):528

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  28. Predicting the eye and hair color from genotype became an established and widely used tool in forensic genetics, as well as in studies of ancient human populations. However, the accuracy of this tool has been ...

    Authors: Elena Balanovska, Elena Lukianova, Janet Kagazezheva, Andrey Maurer, Natalia Leybova, Anastasiya Agdzhoyan, Igor Gorin, Valeria Petrushenko, Maxat Zhabagin, Vladimir Pylev, Elena Kostryukova and Oleg Balanovsky

    Citation: BMC Genomics 2020 21(Suppl 7):527

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  29. According to history, in the pre-Hispanic period, during the conquest and Inka expansion in Ecuador, many Andean families of the Cañar region would have been displaced to several places of Tawantinsuyu, including...

    Authors: José R. Sandoval, Daniela R. Lacerda, Marilza M. S. Jota, Paulo Robles-Ruiz, Pierina Danos, César Paz-y-Miño, Spencer Wells, Fabrício R. Santos and Ricardo Fujita

    Citation: BMC Genomics 2020 21(Suppl 7):413

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  30. Background Telomeres, which are composed of repetitive nucleotide sequences at the end of chromosomes, behave as a division clock that measures replicative senescence. Under the normal physiological condition,...

    Authors: Kyung Hyun Lee and Marek Kimmel

    Citation: BMC Genomics 2020 21(Suppl 9):587

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  31. Haplotypes, the ordered lists of single nucleotide variations that distinguish chromosomal sequences from their homologous pairs, may reveal an individual’s susceptibility to hereditary and complex diseases an...

    Authors: Abishek Sankararaman, Haris Vikalo and François Baccelli

    Citation: BMC Genomics 2020 21(Suppl 9):586

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  32. Single-cell RNA sequencing (scRNA-seq) is a powerful profiling technique at the single-cell resolution. Appropriate analysis of scRNA-seq data can characterize molecular heterogeneity and shed light into the u...

    Authors: Siamak Zamani Dadaneh, Paul de Figueiredo, Sing-Hoi Sze, Mingyuan Zhou and Xiaoning Qian

    Citation: BMC Genomics 2020 21(Suppl 9):585

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  33. B cell affinity maturation enables B cells to generate high-affinity antibodies. This process involves somatic hypermutation of B cell immunoglobulin receptor (BCR) genes and selection by their ability to bind...

    Authors: Xingyu Yang, Christopher M. Tipton, Matthew C. Woodruff, Enlu Zhou, F. Eun-Hyung Lee, Inãki Sanz and Peng Qiu

    Citation: BMC Genomics 2020 21(Suppl 9):583

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  34. Mitogen Activated Protein Kinase (MAPK) cascade is a fundamental pathway in organisms for signal transduction. Though it is well characterized in various plants, there is no systematic study of this cascade in...

    Authors: Archita Chatterjee, Abhirup Paul, G. Meher Unnati, Ruchika Rajput, Trisha Biswas, Tamalika Kar, Srijita Basak, Neelam Mishra, Ashutosh Pandey and Anurag Prakash Srivastava

    Citation: BMC Genomics 2020 21:613

    Content type: Research article

    Published on:

  35. Lysin motif-containing proteins (LYP), which act as pattern-recognition receptors, play central roles in growth, node formation, and responses to biotic stresses. The sequence of Chinese white pear genome (cv....

    Authors: Qiming Chen, Qionghou Li, Xin Qiao, Hao Yin and Shaoling Zhang

    Citation: BMC Genomics 2020 21:612

    Content type: Research article

    Published on:

  36. Anthocyanins determinate the flower color of many plants. Tobacco is a model plant for studying the molecular regulation of flower coloration. We investigated the mechanism underlying flower coloration in toba...

    Authors: Fangchan Jiao, Lu Zhao, Xingfu Wu, Zhongbang Song and Yongping Li

    Citation: BMC Genomics 2020 21:611

    Content type: Research article

    Published on:

  37. Phytohormones are the key factors regulating vascular development in plants, and they are also involved in tension wood (TW) formation. Although the theory of hormone distribution in TW formation is widely sup...

    Authors: Yao Xiao, Fei Yi, Juanjuan Ling, Guijuan Yang, Na Lu, Zirui Jia, Junchen Wang, Kun Zhao, Junhui Wang and Wenjun Ma

    Citation: BMC Genomics 2020 21:609

    Content type: Research article

    Published on:

  38. Sand flies are the vectors of Leishmania parasites. To develop in the sand fly midgut, Leishmania multiplies and undergoes various stage differentiations giving rise to the infective form, the metacyclic promasti...

    Authors: Iliano V. Coutinho-Abreu, Tiago Donatelli Serafim, Claudio Meneses, Shaden Kamhawi, Fabiano Oliveira and Jesus G. Valenzuela

    Citation: BMC Genomics 2020 21:608

    Content type: Research article

    Published on:

  39. Argeia pugettensis is an isopod species that parasitizes other crustaceans. Its huge native geographic range spans the Pacific from China to California, but molecular data are available only for a handful of spec...

    Authors: Jianmei An, Wanrui Zheng, Jielong Liang, Qianqian Xi, Ruru Chen, Junli Jia, Xia Lu and Ivan Jakovlić

    Citation: BMC Genomics 2020 21:607

    Content type: Research article

    Published on:

  40. Immune-response (IR) genes have an important role in the defense against highly variable pathogens, and therefore, diversity in these genomic regions is essential for species’ survival and adaptation. Although...

    Authors: Sara Lado, Jean P. Elbers, Mark F. Rogers, José Melo-Ferreira, Adiya Yadamsuren, Jukka Corander, Petr Horin and Pamela A. Burger

    Citation: BMC Genomics 2020 21:606

    Content type: Research article

    Published on:

  41. Phenotypic performances of livestock animals decline with increasing levels of inbreeding, however, the noticeable decline known as inbreeding depression, may not be due only to the total level of inbreeding, ...

    Authors: Bayode O. Makanjuola, Christian Maltecca, Filippo Miglior, Flavio S. Schenkel and Christine F. Baes

    Citation: BMC Genomics 2020 21:605

    Content type: Research article

    Published on:

  42. The WD40-repeat containing proteins, including DDB1–CUL4-associated factors (DCAFs), are abundant and conserved proteins that play important roles in different cellular processes including spermatogenesis. DCA...

    Authors: Bhavesh V. Mistry, Maha Alanazi, Hanae Fitwi, Olfat Al-Harazi, Mohamed Rajab, Abdullah Altorbag, Falah Almohanna, Dilek Colak and Abdullah M. Assiri

    Citation: BMC Genomics 2020 21:602

    Content type: Research article

    Published on:

  43. It has been reported that nitric oxide (NO) could ameliorate cadmium (Cd) toxicity in tall fescue; however, the underlying mechanisms of NO mediated Cd detoxification are largely unknown. In this study, we inv...

    Authors: Huihui Zhu, Honglian Ai, Zhengrong Hu, Dongyun Du, Jie Sun, Ke Chen and Liang Chen

    Citation: BMC Genomics 2020 21:601

    Content type: Research article

    Published on:

  44. Long non-coding RNAs (lncRNAs) are involved in many fundamental biological processes, such as transcription regulation, protein degradation, and cell differentiation. Information on lncRNA in the melon fly, Zeugo...

    Authors: Wei-Jun Li, Yu-Jia Song, Hong-Liang Han, Hui-Qian Xu, Dong Wei, Guy Smagghe and Jin-Jun Wang

    Citation: BMC Genomics 2020 21:600

    Content type: Research article

    Published on:

  45. Vibriosis has been implicated in major losses of larvae at shellfish hatcheries. However, the species of Vibrio responsible for disease in aquaculture settings and their associated virulence genes are often varia...

    Authors: Hanna Kehlet-Delgado, Claudia C. Häse and Ryan S. Mueller

    Citation: BMC Genomics 2020 21:599

    Content type: Research article

    Published on:

  46. Most animals restrict their activity to a specific part of the day, being diurnal, nocturnal or crepuscular. The genetic basis underlying diurnal preference is largely unknown. Under laboratory conditions, Drosop...

    Authors: Mirko Pegoraro, Laura M. M. Flavell, Pamela Menegazzi, Perrine Colombi, Pauline Dao, Charlotte Helfrich-Förster and Eran Tauber

    Citation: BMC Genomics 2020 21:596

    Content type: Research article

    Published on:

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