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  1. Recent advances in CRISPR technology have enabled us to perform gene knock-in in various species and cell lines. CRISPR-mediated knock-in requires donor DNA which serves as a template for homology-directed rep...

    Authors: Akira Mabuchi, Shoji Hata, Mariya Genova, Chiharu Tei, Kei K. Ito, Masayasu Hirota, Takuma Komori, Masamitsu Fukuyama, Takumi Chinen, Atsushi Toyoda and Daiju Kitagawa
    Citation: BMC Genomics 2023 24:289
    Content type: Research Published on:

  2. Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also...

    Authors: Konrad Sachse, Martin Hölzer, Fabien Vorimore, Lisa-Marie Barf, Carsten Sachse, Karine Laroucau, Manja Marz and Kevin Lamkiewicz
    Citation: BMC Genomics 2023 24:288
    Content type: Research Published on:

  3. DNA methylation is one of the most abundant epigenetic modifications, which plays important roles in flower development, sex differentiation, and regulation of flowering time. Its pattern is affected by cytosi...

    Authors: Qian Wang, Yinquan Qu, Yanhao Yu, Xia Mao and Xiangxiang Fu
    Citation: BMC Genomics 2023 24:287
    Content type: Research Published on:

  5. The genetic locus responsible for duck body size has been fully explained before, but the growth trait-related genetic basis is still waiting to be explored. For example, the genetic site related to growth rat...

    Authors: Yang Xi, Qifan Wu, Yutian Zeng, Jingjing Qi, Junpeng Li, Hua He, Hengyong Xu, Jiwei Hu, Xiping Yan, Lili Bai, Chunchun Han, Shenqiang Hu, Jiwen Wang, Hehe Liu and Liang Li
    Citation: BMC Genomics 2023 24:285
    Content type: Research Published on:

  6. Authors: Mishal Cohen‑Rengifo, Morgane Danion, Anne‑Alicia Gonzalez, Marie‑Laure Begout, Alexandre Cormier, Cyril Noel, Joelle Cabon, Thomas Vitre, Felix C. Mark and David Mazurais
    Citation: BMC Genomics 2023 24:284
    Content type: Correction Published on:

    The original article was published in BMC Genomics 2022 23:448

  7. Testis is the only organ supporting sperm production and with the largest number of proteins and tissue-specific proteins in animals. In our previous studies, we have found that knockdown of ocnus (ocn), a testis...

    Authors: Ya Zheng, Bin Mao, Qian Wang, Xin Duan, Meng-Yan Chen, Wei Shen, Chao Li and Yu-Feng Wang
    Citation: BMC Genomics 2023 24:283
    Content type: Research Published on:

  8. The genus Acidithiobacillus has been widely concerned due to its superior survival and oxidation ability in acid mine drainage (AMD). However, the contribution of insertion sequence (IS) to their biological evolu...

    Authors: Shanshan Huang, Huiying Li, Liyuan Ma, Rui Liu, Yiran Li, Hongmei Wang, Xiaolu Lu, Xinping Huang, Xinhong Wu and Xueduan Liu
    Citation: BMC Genomics 2023 24:282
    Content type: Research Published on:

  9. Cyclic nucleotide-gated ion channels (CNGCs) are nonselective cation channels that are ubiquitous in eukaryotic organisms. As Ca2+ channels, some CNGCs have also proven to be K+-permeable and involved in plant de...

    Authors: Nannan Zhang, Huanzhang Lin, Qiaoying Zeng, Danwen Fu, Xiaoning Gao, Jiayun Wu, Xiaomin Feng, Qinnan Wang, Qiuping Ling and Zilin Wu
    Citation: BMC Genomics 2023 24:281
    Content type: Research Published on:

  11. Piwi-interacting RNAs (piRNAs) have been proven to be closely associated with human diseases. The identification of the potential associations between piRNA and disease is of great significance for complex dis...

    Authors: Xianghan Meng, Junliang Shang, Daohui Ge, Yi Yang, Tongdui Zhang and Jin-Xing Liu
    Citation: BMC Genomics 2023 24:279
    Content type: Research Published on:

  12. Apicomplexa are ancient and diverse organisms which have been poorly characterized by modern genomics. To better understand the evolution and diversity of these single-celled eukaryotes, we sequenced the genom...

    Authors: Andrew J. Mongue, Simon H. Martin, Rachel E. V. Manweiler, Helena Scullion, Jordyn L. Koehn, Jacobus C. de Roode and James R. Walters
    Citation: BMC Genomics 2023 24:278
    Content type: Research Published on:

  14. Despite being in the 21st century, the world has still not been able to vanquish the global AIDS epidemic, and the only foreseeable solution seems to be a safe and effective vaccine. Unfortunately, vaccine trials...

    Authors: Hamza Sher, Hafsa Sharif, Tahreem Zaheer, Sarmad Ahmad Khan, Amjad Ali, Hasnain Javed and Aneela Javed
    Citation: BMC Genomics 2023 24:276
    Content type: Research Published on:

  15. Armillaria species are plant pathogens, but a few Armillaria species can establish a symbiotic relationship with Gastrodia elata, a rootless and leafless orchid, that is used as a Chinese herbal medicine. Armill...

    Authors: Jinlong Cai, Ikram Muhammad, Bilian Chen, Peng Xu, Yiguo Li, Huini Xu and Kunzhi Li
    Citation: BMC Genomics 2023 24:275
    Content type: Research Published on:

  16. The risk of exposure of the general public or military personnel to high levels of ionizing radiation from nuclear weapons or radiological accidents is a dire national security matter. The development of advan...

    Authors: Neetha Nanoth Vellichirammal, Sahil Sethi, Nagavardhini Avuthu, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Chittibabu Guda and Vijay K. Singh
    Citation: BMC Genomics 2023 24:274
    Content type: Research Published on:

  17. Previous studies have shown that secondary metabolites of Bacillus subtilis strain Z15 (BS-Z15) are effective in treating fungal infections in mice. To evaluate whether it also modulates immune function in mice t...

    Authors: Xi-Yuan Cao, Reyihanguli Aimaier, Jun Yang, Jing Yang, Zhong-Yi Chen, Jing-Jing Zhao, Li Yin, Qi Zhang, Jia You, Hui Zhang, Hao-Ran Li, Jia-Yi Chen, Qing-Chen Mao, Li-Ping Yang, Fei Yu, He-Ping Zhao…
    Citation: BMC Genomics 2023 24:273
    Content type: Research Published on:

  18. Macrophages are important effector cells in tumor progression and immune regulation. Previously, we demonstrated that the transcription suppressor homeobox containing 1(HMBOX1) exhibits immunosuppressive activ...

    Authors: Wen Jiang, Yu Jiang, Xinghai Zhang, Hongli Mu, Yuanming Song and Hengli Zhao
    Citation: BMC Genomics 2023 24:272
    Content type: Research Published on:

  19. To reduce the cost of genomic selection, a low-density (LD) single nucleotide polymorphism (SNP) chip can be used in combination with imputation for genotyping selection candidates instead of using a high-dens...

    Authors: Florian Herry, Frédéric Hérault, Frédéric Lecerf, Laëtitia Lagoutte, Mathilde Doublet, David Picard-Druet, Philippe Bardou, Amandine Varenne, Thierry Burlot, Pascale Le Roy and Sophie Allais
    Citation: BMC Genomics 2023 24:271
    Content type: Research Published on:

  20. Ilex pubescens is an important traditional Chinese medicinal plant with many naturally occurring compounds and multiple pharmacological effects. However, the lack of reference genomic information has led to tardi...

    Authors: Peng Zhou, Qiang Zhang, Jiao Li, Fei Li, Jing Huang and Min Zhang
    Citation: BMC Genomics 2023 24:270
    Content type: Research Published on:

  21. Seagull as a migratory wild bird has become most popular species in southwest China since 1980s. Previously, we analyzed the gut microbiota and intestinal pathogenic bacteria configuration for this species by ...

    Authors: Feng Liao, Jing Qian, Ruian Yang, Wenpeng Gu, Rufang Li, Tingting Yang, Xiaoqing Fu, Bing Yuan and Yunhui Zhang
    Citation: BMC Genomics 2023 24:269
    Content type: Research Published on:

  22. The molecular mechanisms underlying the onset and progression of irreversible pulpitis have been studied for decades. Many studies have indicated a potential correlation between autophagy and this disease. Aga...

    Authors: Ye Wang, Qiuyan Xie, Hongwen Yu, Bangyi Zhou, Xiaolan Guo, Buling Wu and Jiao Hu
    Citation: BMC Genomics 2023 24:268
    Content type: Research Published on:

  23. Oriental river prawn Macrobrachium nipponense is an economically important aquaculture species in China, Japan, and Vietnam. In commercial prawn farming, feed cost constitutes about 50 to 65% of the actual variab...

    Authors: Feiyue Ling, Yaoran Fan, Zefei Wang, Nan Xie, Jiale Li, Guiling Wang and Jianbin Feng
    Citation: BMC Genomics 2023 24:267
    Content type: Research Published on:

  24. The prevalence of the COVID-19 disease in recent years and its widespread impact on mortality, as well as various aspects of life around the world, has made it important to study this disease and its viral cau...

    Authors: Saeedeh Akbari Rokn Abadi, Amirhossein Mohammadi and Somayyeh Koohi
    Citation: BMC Genomics 2023 24:266
    Content type: Research Published on:

  25. Cattle (Bos taurus) are a major large livestock, however, compared with other species, the transcriptional specificity of bovine oocyte development has not been emphasised.

    Authors: Fa-Li Zhang, Wei-Dong Li, Geng Zhang, Min Zhang, Zhao-Jun Liu, Ke-Xin Zhu, Qing-Chun Liu, Shu-Er Zhang, Wei Shen and Xi-Feng Zhang
    Citation: BMC Genomics 2023 24:265
    Content type: Research Published on:

  29. Huntiella resides in the Ceratocystidaceae, a family of fungi that accommodates important plant pathogens and insect-associated saprotrophs. Species in the genus have either heterothallic or unisexual (a form of ...

    Authors: Andi M. Wilson, Michael J. Wingfield and Brenda D. Wingfield
    Citation: BMC Genomics 2023 24:261
    Content type: Research Published on:

  30. Human primary hepatocytes (PHCs) are considered to be the best cell source for cell-based therapies for the treatment of end-stage liver disease and acute liver failure. To obtain sufficient and high-quality f...

    Authors: Min Ding, Weijian Huang, Guifen Liu, Bo Zhai, Hexin Yan and Yong Zhang
    Citation: BMC Genomics 2023 24:260
    Content type: Research Published on:

  31. Yellow or stripe rust, caused by the fungus Puccinia striiformis f. sp. tritici (Pst) is an important disease of wheat that threatens wheat production. Since developing resistant cultivars offers a viable solutio...

    Authors: Sandeep Kumar, Dinesh Kumar Saini, Farkhandah Jan, Sofora Jan, Mohd Tahir, Ivica Djalovic, Dragana Latkovic, Mohd Anwar Khan, Sundeep Kumar, V. K. Vikas, Upendra Kumar, Sundip Kumar, Narendra Singh Dhaka, Om Parkash Dhankher, Sachin Rustgi and Reyazul Rouf Mir
    Citation: BMC Genomics 2023 24:259
    Content type: Research Published on:

  32. Bacterial epidemiology needs to understand the spread and dissemination of strains in a One Health context. This is important for highly pathogenic bacteria such as Bacillus anthracis, Brucella species, and Franc...

    Authors: Jörg Linde, Hanka Brangsch, Martin Hölzer, Christine Thomas, Mandy C. Elschner, Falk Melzer and Herbert Tomaso
    Citation: BMC Genomics 2023 24:258
    Content type: Research Published on:

  35. Bread wheat is a recent allohexaploid (genomic constitution AABBDD) that emerged through a hybridization between tetraploid Triticum turgidum (AABB) and diploid Aegilops tauschii (DD) less than 10,000 years ago. ...

    Authors: Meriem Banouh, David Armisen, Annaig Bouguennec, Cécile Huneau, Mamadou Dia Sow, Caroline Pont, Jérôme Salse and Peter Civáň
    Citation: BMC Genomics 2023 24:255
    Content type: Research Published on:

  36. Genomic complexity is a growing field of evolution, with case studies for comparative evolutionary analyses in model and emerging non-model systems. Understanding complexity and the functional components of th...

    Authors: James E. Titus-McQuillan, Adalena V. Nanni, Lauren M. McIntyre and Rebekah L. Rogers
    Citation: BMC Genomics 2023 24:254
    Content type: Research Published on:

  37. Cis-regulatory elements (CRE) are critical for coordinating gene expression programs that dictate cell-specific differentiation and homeostasis. Recently developed self-transcribing active regulatory region se...

    Authors: Kurtis Stefan and Artem Barski
    Citation: BMC Genomics 2023 24:253
    Content type: Research Published on:

  38. The long non-coding RNAs (lncRNAs) are critical regulators of diverse biological processes. Nevertheless, a global view of its expression and function in the mouse retina, a crucial model for neurogenesis stud...

    Authors: Dongliang Yu, Yuqing Wu, Leilei Zhu, Yuying Wang, Donglai Sheng, Xiaofeng Zhao, Guoqing Liang and Lin Gan
    Citation: BMC Genomics 2023 24:252
    Content type: Research Published on:

  39. With the rising demand for entry to extremely high altitudes (HAs), rapid adaptability to extremely hypoxic environments is a challenge that we need to explore. Fasting was used to evaluate acute hypoxia toler...

    Authors: Ruzhou Zhao, Xiaobo Wang, Xiang Zhou, Shuai Jiang, Lin Zhang and Zhibin Yu
    Citation: BMC Genomics 2023 24:251
    Content type: Research Published on:

  40. Rootstocks can improve the chilling tolerance of grafted cucumbers, but their effectiveness varies. Rootstocks with strong de-blooming capacity may result in lower chilling tolerance of grafted cucumbers compa...

    Authors: Qiang Ma, Chenxu Niu, Chao Wang, Chunhua Chen, Yan Li and Min Wei
    Citation: BMC Genomics 2023 24:250
    Content type: Research Published on:

  41. Marine deep subsurface sediments were once thought to be devoid of eukaryotic life, but advances in molecular technology have unlocked the presence and activity of well-known closely related terrestrial and ma...

    Authors: Morgan S. Sobol, Tatsuhiko Hoshino, Victor Delgado, Taiki Futagami, Chihiro Kadooka, Fumio Inagaki and Brandi Kiel Reese
    Citation: BMC Genomics 2023 24:249
    Content type: Research Published on:

  42. Real-time quantitative PCR (RT-qPCR) is a crucial and widely used method for gene expression analysis. Selecting suitable reference genes is extremely important for the accuracy of RT-qPCR results. Commonly us...

    Authors: Jiao Chen, Yunjian Wang, Zhi Yang, Danwen Liu, Yao Jin, Xixi Li, Yuhang Deng, Boya Wang, Zhifeng Zhang and Yubin Ma
    Citation: BMC Genomics 2023 24:248
    Content type: Research Published on:

  43. The Human Leukocyte Antigen (HLA) genes are a group of highly polymorphic genes that are located in the Major Histocompatibility Complex (MHC) region on chromosome 6. The HLA genotype affects the presentabilit...

    Authors: Arne Claeys, Peter Merseburger, Jasper Staut, Kathleen Marchal and Jimmy Van den Eynden
    Citation: BMC Genomics 2023 24:247
    Content type: Research Published on:

  45. Semen cryopreservation is a critical tool for breed improvement and preservation of biodiversity. However, instability of sperm freezability affects its application. The Mediterranean buffalo is one of the riv...

    Authors: Xi Luo, Mingming Liang, Shihai Huang, Qingsong Xue, Xuan Ren, Yanfang Li, Jinli Wang, Deshun Shi and Xiangping Li
    Citation: BMC Genomics 2023 24:245
    Content type: Research Published on:

  47. Sex determination is the process whereby the bipotential embryonic gonads become committed to differentiate into testes or ovaries. In genetic sex determination (GSD), the sex determining trigger is encoded by...

    Authors: Susan Wagner, Sarah L. Whiteley, Meghan Castelli, Hardip R. Patel, Ira W. Deveson, James Blackburn, Clare E. Holleley, Jennifer A. Marshall Graves and Arthur Georges
    Citation: BMC Genomics 2023 24:243
    Content type: Research Published on:

  49. Lineage distribution of Mycobacterium tuberculosis (Mtb) isolates is strongly associated with geographically distinct human populations, and its transmission can be further impacted by the bacterial genome. Howev...

    Authors: Zonglei Zhou, Huaiming Yi, Qingrong Zhou, Luqi Wang, Yue Zhu, Weibing Wang, Zhengwe Liu and Haiyan Xiong
    Citation: BMC Genomics 2023 24:241
    Content type: Research Published on:

  50. Alternative splicing is an important step in gene expression, generating multiple isoforms for the same genes and greatly expanding the diversity of proteomes. Genetic variation in alternative splicing contrib...

    Authors: Fei Zhang, Deborah Velez-Irizarry, Catherine W. Ernst and Wen Huang
    Citation: BMC Genomics 2023 24:240
    Content type: Research Published on:

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