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  1. Content type: Research article

    The core functions of the insulin/insulin-like signaling and target of rapamycin (IIS/TOR) pathway are nutrient sensing, energy homeostasis, growth, and regulation of stress responses. This pathway is also kno...

    Authors: Rita M. Graze, Ruei-Ying Tzeng, Tiffany S. Howard and Michelle N. Arbeitman

    Citation: BMC Genomics 2018 19:893

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  2. Content type: Research article

    The application of genomic data and bioinformatics for the identification of restricted or illegally-sourced natural products is urgently needed. The taxonomic identity and geographic provenance of raw and pro...

    Authors: Kujin Tang, Jie Ren, Richard Cronn, David L. Erickson, Brook G. Milligan, Meaghan Parker-Forney, John L. Spouge and Fengzhu Sun

    Citation: BMC Genomics 2018 19:896

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  3. Content type: Research article

    Malaria parasites are genetically polymorphic and phenotypically plastic. In studying transcriptome variation among parasites from different infections, it is challenging to overcome potentially confounding te...

    Authors: Sarah J. Tarr, Ofelia Díaz-Ingelmo, Lindsay B. Stewart, Suzanne E. Hocking, Lee Murray, Craig W. Duffy, Thomas D. Otto, Lia Chappell, Julian C. Rayner, Gordon A. Awandare and David J. Conway

    Citation: BMC Genomics 2018 19:894

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  4. Content type: Research article

    Selection acts on the phenotype, yet only the genotype is inherited. While both the phenotypic and genotypic response to short-term selection can be measured, the link between these is a major unsolved problem...

    Authors: Ken Kraaijeveld, Vicencio Oostra, Maartje Liefting, Bregje Wertheim, Emile de Meijer and Jacintha Ellers

    Citation: BMC Genomics 2018 19:892

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  5. Content type: Research article

    Expression patterns of many laticifer-specific gens are closely correlative with rubber yield of Hevea brasiliensis (para rubber tree). To unveil the mechanisms underlying the rubber yield, transcript levels of n...

    Authors: Chuntai Wu, Li Lan, Yu Li, Zhiyi Nie and Rizhong Zeng

    Citation: BMC Genomics 2018 19:897

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  6. Content type: Research article

    While the genetics of obesity has been well defined, the epigenetics of obesity is poorly understood. Here, we used a genome-wide approach to identify genes with differences in both DNA methylation and express...

    Authors: Madeline Rose Keleher, Rabab Zaidi, Lauren Hicks, Shyam Shah, Xiaoyun Xing, Daofeng Li, Ting Wang and James M. Cheverud

    Citation: BMC Genomics 2018 19:888

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  7. Content type: Research article

    Pectobacterium spp. are necrotrophic bacterial plant pathogens of the family Pectobacteriaceae, responsible for a wide spectrum of diseases of important crops and ornamental plants including soft rot, blackleg, a...

    Authors: Xiaoying Li, Yali Ma, Shuqing Liang, Yu Tian, Sanjun Yin, Sisi Xie and Hua Xie

    Citation: BMC Genomics 2018 19:889

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  8. Content type: Research article

    Even though microsatellite loci frequently have been isolated using recently developed next-generation sequencing (NGS) techniques, this task is still difficult because of the subsequent polymorphism screening...

    Authors: Yun Xia, Wei Luo, Siqi Yuan, Yuchi Zheng and Xiaomao Zeng

    Citation: BMC Genomics 2018 19:886

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  9. Content type: Research article

    Restriction-modification (R-M) systems protect bacteria and archaea from attacks by bacteriophages and archaeal viruses. An R-M system specifically recognizes short sites in foreign DNA and cleaves it, while s...

    Authors: I. S. Rusinov, A. S. Ershova, A. S. Karyagina, S. A. Spirin and A. V. Alexeevski

    Citation: BMC Genomics 2018 19:885

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  10. Content type: Research article

    The most common infusion in southern Latin-American countries is prepared with dried leaves of Ilex paraguariensis A. St.-Hil., an aboriginal ancestral beverage known for its high polyphenols concentration curren...

    Authors: Jessica V. Fay, Christopher J. Watkins, Ram K. Shrestha, Sergio L. Litwiñiuk, Liliana N. Talavera Stefani, Cristian A. Rojas, Carina F. Argüelles, Julian A. Ferreras, Mario Caccamo and Marcos M. Miretti

    Citation: BMC Genomics 2018 19:891

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  11. Content type: Research article

    Many large-effect quantitative trait loci (QTLs) for yield and disease resistance related traits have been identified in different mapping populations of peanut (Arachis hypogaea L.) under multiple environments. ...

    Authors: Qing Lu, Hao Liu, Yanbin Hong, Haifen Li, Haiyan Liu, Xingyu Li, Shijie Wen, Guiyuan Zhou, Shaoxiong Li, Xiaoping Chen and Xuanqiang Liang

    Citation: BMC Genomics 2018 19:887

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  12. Content type: Research article

    The facultatively anaerobic thermophile Parageobacillus thermoglucosidasius produces hydrogen gas (H2) by coupling CO oxidation to proton reduction in the water-gas shift (WGS) reaction via a carbon monoxide dehy...

    Authors: Teresa Mohr, Habibu Aliyu, Raphael Küchlin, Michaela Zwick, Don Cowan, Anke Neumann and Pieter de Maayer

    Citation: BMC Genomics 2018 19:880

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  13. Content type: Research article

    Upland Cotton (Gossypium hirsutum) is a very important cash crop known for its high quality natural fiber. Recent advances in sequencing technologies provide powerful tools with which to explore the cotton genome...

    Authors: Iftikhar Ali, Zhonghua Teng, Yuting Bai, Qing Yang, Yongshui Hao, Juan Hou, Yongbin Jia, Lixia Tian, Xueying Liu, Zhaoyun Tan, Wenwen Wang, Kiirya Kenneth, Abdalla Yousef Ahmed Sharkh, Dexin Liu, Kai Guo, Jian Zhang…

    Citation: BMC Genomics 2018 19:879

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  14. Content type: Research article

    The eukaryotic unicellular protist Plasmodiophora brassicae is an endocellular parasite of cruciferous plants. In host cortical cells, this protist develops a unicellular structure that is termed the plasmodium. ...

    Authors: Kai Bi, Tao Chen, Zhangchao He, Zhixiao Gao, Ying Zhao, Yanping Fu, Jiasen Cheng, Jiatao Xie and Daohong Jiang

    Citation: BMC Genomics 2018 19:881

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  15. Content type: Research article

    In upland cotton (Gossypium hirsutum L.), genotypes with the same mature fiber length (FL) might possess different genes and exhibit differential expression of genes related to fiber elongation at different fiber...

    Authors: Jianjiang Ma, Yanhui Geng, Wenfeng Pei, Man Wu, Xingli Li, Guoyuan Liu, Dan Li, Qifeng Ma, XinShan Zang, Shuxun Yu, Jinfa Zhang and Jiwen Yu

    Citation: BMC Genomics 2018 19:882

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  16. Content type: Research article

    The health and resilience of species in natural environments is increasingly challenged by complex anthropogenic stressor combinations including climate change, habitat encroachment, and chemical contamination...

    Authors: Kurt A. Gust, Vijender Chaitankar, Preetam Ghosh, Mitchell S. Wilbanks, Xianfeng Chen, Natalie D. Barker, Don Pham, Leona D. Scanlan, Arun Rawat, Larry G. Talent, Michael J. Quinn Jr, Christopher D. Vulpe, Mohamed O. Elasri, Mark S. Johnson, Edward J. Perkins and Craig A. McFarland

    Citation: BMC Genomics 2018 19:877

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  17. Content type: Research article

    Essential genes are required for an organism’s viability and their functions can vary greatly, spreading across many pathways. Due to the importance of essential genes, large scale efforts have been undertaken...

    Authors: Shicheng Yu, Chaoran Zheng, Fan Zhou, David L. Baillie, Ann M. Rose, Zixin Deng and Jeffrey Shih-Chieh Chu

    Citation: BMC Genomics 2018 19:871

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  18. Content type: Research article

    Copy number variants (CNVs) have been shown to increase risk for physical anomalies, developmental, psychiatric and medical disorders. Some of them have been associated with changes in weight, height, and othe...

    Authors: David Owen, Mathew Bracher-Smith, Kimberley M. Kendall, Elliott Rees, Mark Einon, Valentina Escott-Price, Michael J. Owen, Michael C. O’Donovan and George Kirov

    Citation: BMC Genomics 2018 19:867

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  19. Content type: Research article

    Environmental stress induced genetic polymorphisms have been suggested to arbitrate functional modifications influencing adaptations in microbes. The relationship between the genetic processes and concomitant ...

    Authors: Akanksha Jaiswar, Deepti Varshney, Alok Adholeya and Pushplata Prasad

    Citation: BMC Genomics 2018 19:868

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  20. Content type: Research article

    Similar to other urban trees, holm oaks (Quercus ilex L.) provide a physiological, ecological and social service in the urban environment, since they remove atmospheric pollution. However, the urban environment h...

    Authors: Lucia Natali, Alberto Vangelisti, Lucia Guidi, Damiano Remorini, Lorenzo Cotrozzi, Giacomo Lorenzini, Cristina Nali, Elisa Pellegrini, Alice Trivellini, Paolo Vernieri, Marco Landi, Andrea Cavallini and Tommaso Giordani

    Citation: BMC Genomics 2018 19:872

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  21. Content type: Research article

    Corynebacterium diphtheriae is the main etiological agent of diphtheria, a global disease causing life-threatening infections, particularly in infants and children. Vaccination with diphtheria toxoid protects aga...

    Authors: Verlaine J. Timms, Trang Nguyen, Taryn Crighton, Marion Yuen and Vitali Sintchenko

    Citation: BMC Genomics 2018 19:869

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  22. Content type: Research article

    Taraxacum kok-saghyz R. (Tks) is a promising alternative species to Hevea brasiliensis for production of high quality natural rubber (NR). A comparative transcriptome analysis of plants with differential producti...

    Authors: Francesco Panara, Loredana Lopez, Loretta Daddiego, Elio Fantini, Paolo Facella and Gaetano Perrotta

    Citation: BMC Genomics 2018 19:875

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  23. Content type: Research article

    The goat is an important farm animal. Reproduction is an important process of goat farming. The ovary is the most important reproductive organ for goats. In recent years, an increasing number of long non-codin...

    Authors: Yong Liu, Bing Qi, Juan Xie, Xiaoqing Wu, Yinghui Ling, Xinyan Cao, Feng Kong, Jing Xin, Xin Jiang, Qiaoqin Wu, Wenying Wang, Qingmei Li, Shengnan Zhang, Fengrui Wu, Di Zhang, Rong Wang…

    Citation: BMC Genomics 2018 19:866

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  24. Content type: Research article

    Rapid and accurate identification of Verotoxigenic Escherichia coli (VTEC) O157:H7 is dependent on well-established, standardized and highly discriminatory typing methods. Currently, conventional subtyping tests ...

    Authors: Jillian Rumore, Lorelee Tschetter, Ashley Kearney, Rima Kandar, Rachel McCormick, Matthew Walker, Christy-Lynn Peterson, Aleisha Reimer and Celine Nadon

    Citation: BMC Genomics 2018 19:870

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  25. Content type: Research article

    Varicella zoster virus (VZV) is a human pathogenic alphaherpesvirus harboring a relatively large DNA molecule. The VZV transcriptome has already been analyzed by microarray and short-read sequencing analyses. ...

    Authors: István Prazsák, Norbert Moldován, Zsolt Balázs, Dóra Tombácz, Klára Megyeri, Attila Szűcs, Zsolt Csabai and Zsolt Boldogkői

    Citation: BMC Genomics 2018 19:873

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  26. Content type: Research article

    Silene vulgaris (bladder campion) is a gynodioecious species existing as two genders – male-sterile females and hermaphrodites. Cytoplasmic male sterility (CMS) is generally encoded by mitochondrial genes, which ...

    Authors: Helena Štorchová, James D. Stone, Daniel B. Sloan, Oushadee A. J. Abeyawardana, Karel Müller, Jana Walterová and Marie Pažoutová

    Citation: BMC Genomics 2018 19:874

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  27. Content type: Research article

    Corn dried distillers grains with solubles (cDDGS) are a byproduct of biofuel and alcohol production. cDDGS have been used in pig feed for many years, because they are readily available and rich in protein, fi...

    Authors: Maria Oczkowicz, Tomasz Szmatoła, Małgorzata Świątkiewicz, Klaudia Pawlina-Tyszko, Artur Gurgul and Tomasz Ząbek

    Citation: BMC Genomics 2018 19:864

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  28. Content type: Research article

    The dramatic increase in myotomal muscle mass in post-hatching fish is related to their ability to lastingly produce new muscle fibres, a process termed hyperplasia. The molecular and cellular mechanisms under...

    Authors: Sabrina Jagot, Nathalie Sabin, Aurélie Le Cam, Jérôme Bugeon, Pierre-Yves Rescan and Jean-Charles Gabillard

    Citation: BMC Genomics 2018 19:865

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  29. Content type: Research article

    Nicotiana rustica (Aztec tobacco), like common tobacco (Nicotiana tabacum), is an allotetraploid formed through a recent hybridization event; however, it originated from completely different progenitor species. H...

    Authors: N. Sierro, J. N. D. Battey, L. Bovet, V. Liedschulte, S. Ouadi, J. Thomas, H. Broye, H. Laparra, A. Vuarnoz, G. Lang, S. Goepfert, M. C. Peitsch and N. V. Ivanov

    Citation: BMC Genomics 2018 19:855

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  30. Content type: Research article

    Exoribonucleases are crucial for RNA degradation in Escherichia coli but the roles of RNase R and PNPase and their potential overlap in stationary phase are not well characterized. Here, we used a genome-wide app...

    Authors: Clémentine Dressaire, Vânia Pobre, Sandrine Laguerre, Laurence Girbal, Cecilia Maria Arraiano and Muriel Cocaign-Bousquet

    Citation: BMC Genomics 2018 19:848

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  31. Content type: Research article

    Chemosensation is a critical signalling process for all organisms and is achieved through the interaction between chemosensory receptors and their ligands. The Crown-of-thorns starfish, Acanthaster planci species...

    Authors: R. E. Roberts, D. Powell, T. Wang, M. H. Hall, C. A. Motti and S. F. Cummins

    Citation: BMC Genomics 2018 19:853

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  32. Content type: Research article

    Photorhabdus luminescens is an enteric bacterium, which lives in mutualistic association with soil nematodes and is highly pathogenic for a broad spectrum of insects. A complete genome sequence for the type strai...

    Authors: Maria-Antonia Zamora-Lagos, Simone Eckstein, Angela Langer, Athanasios Gazanis, Friedhelm Pfeiffer, Bianca Habermann and Ralf Heermann

    Citation: BMC Genomics 2018 19:854

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  33. Content type: Research article

    Spinach downy mildew caused by the oomycete Peronospora effusa is a significant burden on the expanding spinach production industry, especially for organic farms where synthetic fungicides cannot be deployed to c...

    Authors: Kyle Fletcher, Steven J. Klosterman, Lida Derevnina, Frank Martin, Lien D. Bertier, Steven Koike, Sebastian Reyes-Chin-Wo, Beiquan Mou and Richard Michelmore

    Citation: BMC Genomics 2018 19:851

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  34. Content type: Research article

    Plasmodium falciparum exhibits resistance to the artemisinin component of the frontline antimalarial treatment Artemisinin-based Combination Therapy in South East Asia. Millions of lives will be at risk if artemi...

    Authors: Justin Gibbons, Katrina A. Button-Simons, Swamy R. Adapa, Suzanne Li, Maxwell Pietsch, Min Zhang, Xiangyun Liao, John H. Adams, Michael T. Ferdig and Rays H. Y. Jiang

    Citation: BMC Genomics 2018 19:849

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  35. Content type: Research article

    Southern root-knot nematode Meloidogyne incognita (Kofoid and White, 1919), Chitwood, 1949 is a key pest of agricultural crops. Pasteuria penetrans is a hyperparasitic bacterium capable of suppressing the nematod...

    Authors: Victor Phani, Vishal S. Somvanshi, Rohit N. Shukla, Keith G. Davies and Uma Rao

    Citation: BMC Genomics 2018 19:850

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  36. Content type: Research article

    Thiazolidinone derivatives show inhibitory activity (IC50) against the Toxoplasma gondii parasite, as well as high selectivity with high therapeutic index. To disclose the target proteins of the thiazolidinone co...

    Authors: Diego Molina, Rodrigo Cossio-Pérez, Cristian Rocha-Roa, Lina Pedraza, Edwar Cortes, Alejandro Hernández and Jorge E. Gómez-Marín

    Citation: BMC Genomics 2018 19:856

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  37. Content type: Research article

    The green peach aphid (GPA), Myzus persicae (Sülzer), is a widespread phloem-feeding insect that significantly influences the yield and visual quality of peach [Prunus persica (L.) Batsch]. Single dominant gene (

    Authors: Liang Niu, Lei Pan, Wenfang Zeng, Zhenhua Lu, Guochao Cui, Meili Fan, Qiang Xu, Zhiqiang Wang and Guohuai Li

    Citation: BMC Genomics 2018 19:846

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  38. Content type: Research article

    Leishmaniasis is a neglected tropical disease with diverse clinical phenotypes, determined by parasite, host and vector interactions. Despite the advances in molecular biology and the availability of more Leishma...

    Authors: Sumudu R. Samarasinghe, Nilakshi Samaranayake, Udeshika L. Kariyawasam, Yamuna D. Siriwardana, Hideo Imamura and Nadira D. Karunaweera

    Citation: BMC Genomics 2018 19:843

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  39. Content type: Research article

    Increased attention is being paid to breast muscle yield and meat quality in the duck breeding industry. Our previous report has demonstrated that dietary Clostridium butyricum (C. butyricum) can improve meat qua...

    Authors: Yanhan Liu, Yaxiong Jia, Cun Liu, Limin Ding and Zhaofei Xia

    Citation: BMC Genomics 2018 19:844

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  40. Content type: Research article

    Pyropia yezoensis is an important marine crop which, due to its high protein content, is widely used as a seafood in China. Unfortunately, red rot disease, caused by Pythium porphyrae, seriously damages P. yezoen...

    Authors: Sohrab Khan, Yunxiang Mao, Dong Gao, Sadaf Riaz, Zeeshan Niaz, Lei Tang, Sohaib Khan and Dongmei Wang

    Citation: BMC Genomics 2018 19:842

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  41. Content type: Methodology article

    Copy Number Alternations (CNAs) is defined as somatic gain or loss of DNA regions. The profiles of CNAs may provide a fingerprint specific to a tumor type or tumor grade. Low-coverage sequencing for reporting ...

    Authors: Sangdi Lin, Chen Wang, Shabnam Zarei, Debra A. Bell, Sarah E. Kerr, George C. Runger and Jean-Pierre A. Kocher

    Citation: BMC Genomics 2018 19:841

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  42. Content type: Research article

    Skeletal muscle satellite cells (MSC) are crucial for postnatal growth and regeneration of skeletal muscle. An interaction exists between MSC and intramuscular preadipocytes (IMPA). This study is the first to ...

    Authors: Liping Guo, Huanxian Cui, Guiping Zhao, Ranran Liu, Qinghe Li, Maiqing Zheng, Yuming Guo and Jie Wen

    Citation: BMC Genomics 2018 19:838

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  43. Content type: Research article

    An increasing number of studies reported that exogenous miRNAs (xenomiRs) can be detected in animal bodies, however, some others reported negative results. Some attributed this divergence to the selective abso...

    Authors: Qi Zhao, Qian Mao, Zheng Zhao, Tongyi Dou, Zhiguo Wang, Xiaoyu Cui, Yuanning Liu and Xiaoya Fan

    Citation: BMC Genomics 2018 19:839

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  44. Content type: Research article

    Nε-Acetylation of lysine residues, a frequently occurring post-translational modification, plays important functions in regulating physiology and metabolism. However, the information of global overview of protei....

    Authors: Jutang Jiang, Zhongshuai Gai, Yu Wang, Kai Fan, Litao Sun, Hui Wang and Zhaotang Ding

    Citation: BMC Genomics 2018 19:840

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  45. Content type: Research article

    Acetogenic bacteria constitute promising biocatalysts for the conversion of CO2/H2 or synthesis gas (H2/CO/CO2) into biofuels and value-added biochemicals. These microorganisms are naturally capable of autotrophi...

    Authors: Yoseb Song, Jongoh Shin, Sangrak Jin, Jung-Kul Lee, Dong Rip Kim, Sun Chang Kim, Suhyung Cho and Byung-Kwan Cho

    Citation: BMC Genomics 2018 19:837

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