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  1. Previous study reported that patients who suffered coronary heart disease (CHD) complicated with non-alcoholic fatty liver disease (NAFLD) had worse cardiac function and clinical outcomes than patients with CH...

    Authors: Yiwen Zhang, Jun Xu, Xuemei Wang, Xinhua Ren and Yulan Liu

    Citation: BMC Genomics 2019 20:862

    Content type: Research article

    Published on:

  2. Elymus sibiricus is an ecologically and economically important perennial, self-pollinated, and allotetraploid (StStHH) grass, widely used for forage production and animal husbandry in Western and Northern China. ...

    Authors: Zongyu Zhang, Wengang Xie, Junchao Zhang, Na Wang, Yongqiang Zhao, Yanrong Wang and Shiqie Bai

    Citation: BMC Genomics 2019 20:861

    Content type: Research article

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  3. The incidence of dementia and cognitive decline is increasing with no therapy or cure. One of the reasons treatment remains elusive is because there are various pathologies that contribute to age-related cogni...

    Authors: Kate E. Foley, Hongtian Stanley Yang, Leah C. Graham and Gareth R. Howell

    Citation: BMC Genomics 2019 20:860

    Content type: Research article

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  4. The protozoan pathogen Toxoplasma gondii has the unique ability to develop a chronic infection in the brain of its host by transitioning from the fast growing tachyzoite morphology to latent bradyzoite morphology...

    Authors: Andrew L. Garfoot, Gary M. Wilson, Joshua J. Coon and Laura J. Knoll

    Citation: BMC Genomics 2019 20:859

    Content type: Research article

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  5. APOBEC1 (A1) enzymes are cytidine deaminases involved in RNA editing. In addition to this activity, a few A1 enzymes have been shown to be active on single stranded DNA. As two human ssDNA cytidine deaminases ...

    Authors: Vincent Caval, Wenjuan Jiao, Noémie Berry, Pierre Khalfi, Emmanuelle Pitré, Valérie Thiers, Jean-Pierre Vartanian, Simon Wain-Hobson and Rodolphe Suspène

    Citation: BMC Genomics 2019 20:858

    Content type: Research article

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  6. Saffron crocus (Crocus sativus) is a valuable spice with medicinal uses in gynaecopathia and nervous system diseases. Identify flowering regulatory genes plays a vital role in increasing flower numbers, thereby r...

    Authors: Xiaodong Qian, Youping Sun, Guifen Zhou, Yumei Yuan, Jing Li, Huilian Huang, Limin Xu and Liqin Li

    Citation: BMC Genomics 2019 20:857

    Content type: Research article

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  7. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long ncRNAs (lncRNAs) and circular RNAs (circRNAs), accomplish remarkable variety of biological functions. However, the composition of ncRNAs and their in.....

    Authors: Xi Chen, Shuo Sun, Fangjie Liu, Enhui Shen, Lu Liu, Chuyu Ye, Bingguang Xiao, Michael P. Timko, Qian-Hao Zhu, Longjiang Fan and Peijian Cao

    Citation: BMC Genomics 2019 20:856

    Content type: Research article

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  8. Annelids exhibit remarkable postembryonic developmental abilities. Most annelids grow during their whole life by adding segments through the action of a segment addition zone (SAZ) located in front of the pygi...

    Authors: Rannyele Passos Ribeiro, Guillermo Ponz-Segrelles, Christoph Bleidorn and Maria Teresa Aguado

    Citation: BMC Genomics 2019 20:855

    Content type: Research article

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  9. The ureagenesis plays a central role in the homeostatic control of nitrogen metabolism. This process occurs in the liver, the key metabolic organ in the maintenance of energy homeostasis in the body. To date, ...

    Authors: Zhongyan Lu, Zhihui Xu, Zanming Shen, Hong Shen and Jörg R. Aschenbach

    Citation: BMC Genomics 2019 20:854

    Content type: Research article

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  10. Enzymatic plant biomass degradation by fungi is a highly complex process and one of the leading challenges in developing a biobased economy. Some industrial fungi (e.g. Aspergillus niger) have a long history of u...

    Authors: Claire Khosravi, Joanna E. Kowalczyk, Tania Chroumpi, Evy Battaglia, Maria-Victoria Aguilar Pontes, Mao Peng, Ad Wiebenga, Vivian Ng, Anna Lipzen, Guifen He, Diane Bauer, Igor V. Grigoriev and Ronald P. de Vries

    Citation: BMC Genomics 2019 20:853

    Content type: Research article

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  11. Cleft lip (CL), one of the most common congenital birth defects, shows considerable geographic and ethnic variation, with contribution of both genetic and environmental factors. Mouse genetic studies have iden...

    Authors: Akiko Suzuki, Hiroki Yoshioka, Dima Summakia, Neha G. Desai, Goo Jun, Peilin Jia, David S. Loose, Kenichi Ogata, Mona V. Gajera, Zhongming Zhao and Junichi Iwata

    Citation: BMC Genomics 2019 20:852

    Content type: Research article

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  12. Endogenous α-synuclein (α-Syn) is involved in many pathophysiological processes in the secondary injury stage after acute spinal cord injury (SCI), and the mechanism governing these functions has not been thor...

    Authors: Hong Zeng, Bao-fu Yu, Nan Liu, Yan-yan Yang, Hua-yi Xing, Xiao-xie Liu and Mou-wang Zhou

    Citation: BMC Genomics 2019 20:851

    Content type: Research article

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  13. The MinION Access Program (MAP, 2014–2016) allowed selected users to test the prospects of long nanopore reads for diverse organisms and applications through the rapid development of improving chemistries. In ...

    Authors: Thomas Sauvage, William E. Schmidt, Hwan Su Yoon, Valerie J. Paul and Suzanne Fredericq

    Citation: BMC Genomics 2019 20:850

    Content type: Research article

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  14. micro RNA (miRNA) are important regulators of gene expression and may influence phenotypes and disease traits. The connection between genetics and miRNA expression can be determined through expression quantita...

    Authors: Gordon Kordas, Pratyaydipta Rudra, Audrey Hendricks, Laura Saba and Katerina Kechris

    Citation: BMC Genomics 2019 20:849

    Content type: Research article

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  15. Insertions/deletions (InDels) and more specifically presence/absence variations (PAVs) are pervasive in several species and have strong functional and phenotypic effect by removing or drastically modifying gen...

    Authors: Clément Mabire, Jorge Duarte, Aude Darracq, Ali Pirani, Hélène Rimbert, Delphine Madur, Valérie Combes, Clémentine Vitte, Sébastien Praud, Nathalie Rivière, Johann Joets, Jean-Philippe Pichon and Stéphane D. Nicolas

    Citation: BMC Genomics 2019 20:848

    Content type: Methodology article

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  17. Recent studies have shown that long non-coding RNAs (lncRNAs) play a crucial role in the induction of cancer through epigenetic regulation, transcriptional regulation, post-transcriptional regulation and other...

    Authors: Tao Chen, Cangui Zhang, Yingqiao Liu, Yuyun Zhao, Dingyi Lin, Yanfeng Hu, Jiang Yu and Guoxin Li

    Citation: BMC Genomics 2019 20:846

    Content type: Research article

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  18. To understand the genetic mechanisms of insect herbivory, the transcriptional response of insects feeding on different host plant species has to be studied. Here, we generated gene expression data of the gener...

    Authors: Thijmen Breeschoten, Vera I. D. Ros, M. Eric Schranz and Sabrina Simon

    Citation: BMC Genomics 2019 20:845

    Content type: Research article

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  19. Cultivated peanut (Arachis hypogaea L.) is an important oil and protein crop, but it has low disease resistance; therefore, it is important to reveal the number, sequence features, function, and evolution of gene...

    Authors: Hui Song, Zhonglong Guo, Xiaohui Hu, Lang Qian, Fuhong Miao, Xiaojun Zhang and Jing Chen

    Citation: BMC Genomics 2019 20:844

    Content type: Research article

    Published on:

  20. Intraspecific variations among induced responses might lead to understanding of adaptive variations in defense strategies against insects. We employed RNA-Seq transcriptome screening to elucidate the molecular...

    Authors: Ariel Ogran, Adi Faigenboim and Oz Barazani

    Citation: BMC Genomics 2019 20:843

    Content type: Research article

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  21. Recent advances in genomic technologies have facilitated genome-wide investigation of human genetic variations. However, most efforts have focused on the major populations, yet trio genomes of indigenous popul...

    Authors: Lian Deng, Haiyi Lou, Xiaoxi Zhang, Bhooma Thiruvahindrapuram, Dongsheng Lu, Christian R. Marshall, Chang Liu, Bo Xie, Wanxing Xu, Lai-Ping Wong, Chee-Wei Yew, Aghakhanian Farhang, Rick Twee-Hee Ong, Mohammad Zahirul Hoque, Abdul Rahman Thuhairah, Bhak Jong…

    Citation: BMC Genomics 2019 20:842

    Content type: Research article

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  22. Fusarium graminearum is a destructive fungal pathogen of wheat, barley and other small grain cereals. During plant infection, the pathogen produces trichothecene mycotoxin deoxynivalenol (DON), which is harmful t...

    Authors: Shanyue Zhou and Chunlan Wu

    Citation: BMC Genomics 2019 20:841

    Content type: Research article

    Published on:

  23. Subfertility is a major issue facing the dairy industry as the average US Holstein cow conception rate (CCR) is approximately 35%. The genetics underlying the physiological processes responsible for CCR, the p...

    Authors: Jennifer N. Kiser, Erin Clancey, Joao G. N. Moraes, Joseph Dalton, Gregory W. Burns, Thomas E. Spencer and Holly L. Neibergs

    Citation: BMC Genomics 2019 20:840

    Content type: Research article

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  24. Weeping lovegrass (Eragrostis curvula [Shrad.] Nees) is a perennial grass found in semi-arid regions that is well adapted for growth in sandy soils and drought conditions. E. curvula constitutes a polymorphic com...

    Authors: Ingrid Garbus, Juan Pablo Selva, María Cielo Pasten, Andrés Martín Bellido, José Carballo, Emidio Albertini and Viviana Echenique

    Citation: BMC Genomics 2019 20:839

    Content type: Research article

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  25. Pachycladon cheesemanii is a close relative of Arabidopsis thaliana and is an allotetraploid perennial herb which is widespread in the South Island of New Zealand. It grows at altitudes of up to 1000 m where it i...

    Authors: Yanni Dong, Saurabh Gupta, Rixta Sievers, Jason J. Wargent, David Wheeler, Joanna Putterill, Richard Macknight, Tsanko Gechev, Bernd Mueller-Roeber and Paul P. Dijkwel

    Citation: BMC Genomics 2019 20:838

    Content type: Research article

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  26. Cytoplasmic male sterility (CMS) and its restoration of fertility (Rf) system is an important mechanism to produce F1 hybrid seeds. Understanding the interaction that controls restoration at a molecular level wil...

    Authors: Bingqiang Wei, Lanlan Wang, Paul W. Bosland, Gaoyuan Zhang and Ru Zhang

    Citation: BMC Genomics 2019 20:837

    Content type: Research article

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  27. The Metarhizium genus harbors important entomopathogenic fungi. These species have been widely explored as biological control agents, and strategies to improve the fungal virulence are under investigation. Thus, ...

    Authors: Nicolau Sbaraini, Reinaldo Bellini, Augusto Bartz Penteriche, Rafael Lucas Muniz Guedes, Ane Wichine Acosta Garcia, Alexandra Lehmkuhl Gerber, Marilene Henning Vainstein, Ana Tereza Ribeiro de Vasconcelos, Augusto Schrank and Charley Christian Staats

    Citation: BMC Genomics 2019 20:836

    Content type: Research article

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  28. Tail-anchored membrane proteins (TAMPs) differ from other integral membrane proteins, because they contain a single transmembrane domain at the extreme carboxyl-terminus and are therefore obliged to target to ...

    Authors: Glauber Costa Brito, Wiebke Schormann, Satinder K. Gidda, Robert T. Mullen and David W. Andrews

    Citation: BMC Genomics 2019 20:835

    Content type: Research article

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  29. The genus Hosta is a group of economically appreciated perennial herbs consisting of approximately 25 species that is endemic to eastern Asia. Due to considerable morphological variability, the genus has been wel...

    Authors: Soo-Rang Lee, Kyeonghee Kim, Byoung-Yoon Lee and Chae Eun Lim

    Citation: BMC Genomics 2019 20:833

    Content type: Research article

    Published on:

  30. Machine learning can effectively nominate novel genes for various research purposes in the laboratory. On a genome-wide scale, we implemented multiple databases and algorithms to predict and prioritize the human

    Authors: Masoud Arabfard, Mina Ohadi, Vahid Rezaei Tabar, Ahmad Delbari and Kaveh Kavousi

    Citation: BMC Genomics 2019 20:832

    Content type: Research article

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  31. Formalin-fixed and paraffin-embedded (FFPE) blocks held in clinical laboratories are an invaluable resource for clinical research, especially in the era of personalized medicine. It is important to accurately ...

    Authors: Xiaojing Lin, Lihong Qiu, Xue Song, Junyan Hou, Weizhi Chen and Jun Zhao

    Citation: BMC Genomics 2019 20:831

    Content type: Methodology article

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  32. Similar to humans, the zebrafish brain plays a central role in regulating sexual reproduction, maturation and sexual behavior. However, systematic studies of the dimorphic patterns of gene expression in the br...

    Authors: Wenliang Yuan, Shouwen Jiang, Dan Sun, Zhichao Wu, Cai Wei, Chaoxu Dai, Linhua Jiang and Sihua Peng

    Citation: BMC Genomics 2019 20:830

    Content type: Research article

    Published on:

  33. Scylla paramamosain is a commercially important mud crab. The microbiota is a community that inhabits the crab intestine, and is important for physiological functional and host health.

    Authors: Hongling Wei, Huan Wang, Lei Tang, Changkao Mu, Chunyu Ye, Lizhi Chen and Chunlin Wang

    Citation: BMC Genomics 2019 20:829

    Content type: Research article

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  34. The merging of two divergent genomes during hybridization can result in the remodeling of parental gene expression in hybrids. A molecular basis underling expression change in hybrid is regulatory divergence, ...

    Authors: Min Zhang, Yi-Wei Tang, Ji Qi, Xin-Kai Liu, Dan-Feng Yan, Nai-Sheng Zhong, Nai-Qi Tao, Ji-Yin Gao, Yu-Guo Wang, Zhi-Ping Song, Ji Yang and Wen-Ju Zhang

    Citation: BMC Genomics 2019 20:828

    Content type: Research article

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  35. Dual-purpose cattle are more adaptive to environmental challenges than single-purpose dairy or beef cattle. Balance among milk, reproductive, and mastitis resistance traits in breeding programs is therefore mo...

    Authors: Jinghang Zhou, Liyuan Liu, Chunpeng James Chen, Menghua Zhang, Xin Lu, Zhiwu Zhang, Xixia Huang and Yuangang Shi

    Citation: BMC Genomics 2019 20:827

    Content type: Research article

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  36. Upon exposure to unfavorable environmental conditions, plants need to respond quickly to maintain their homeostasis. For instance, physiological, biochemical and transcriptional changes occur during plant-path...

    Authors: Marco Tulio Solano-De la Cruz, Jacel Adame-García, Josefat Gregorio-Jorge, Verónica Jiménez-Jacinto, Leticia Vega-Alvarado, Lourdes Georgina Iglesias-Andreu, Esteban Elías Escobar-Hernández and Mauricio Luna-Rodríguez

    Citation: BMC Genomics 2019 20:826

    Content type: Research article

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  37. 5-Azacytidine (5-azaC) promotes the development of ‘Kyoho’ grape berry but the associated changes in gene expression have not been reported. In this study, we performed transcriptome analysis of grape berry at...

    Authors: Da-Long Guo, Qiong Li, Xiao-Ru Ji, Zhen-Guang Wang and Yi-He Yu

    Citation: BMC Genomics 2019 20:825

    Content type: Research article

    Published on:

  38. Alternative polyadenylation is commonly examined using cDNA sequencing, which is known to be affected by template-switching artifacts. However, the effects of such template-switching artifacts on alternative p...

    Authors: Zsolt Balázs, Dóra Tombácz, Zsolt Csabai, Norbert Moldován, Michael Snyder and Zsolt Boldogkői

    Citation: BMC Genomics 2019 20:824

    Content type: Research article

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  39. As one of the most described epigenetic marks in human cancers, DNA methylation plays essential roles in gene expression regulation and has been implicated in the prognosis and therapeutics of many cancers. We...

    Authors: Xiao Chen, Jianying Zhang and Xiaofeng Dai

    Citation: BMC Genomics 2019 20:823

    Content type: Research article

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  40. The enhancing incidence of carbapenem-resistant Klebsiella pneumoniae (CRKP)-mediated infections in Mengchao Hepatobiliary Hospital of Fujian Medical University in 2017 is the motivation behind this investigation...

    Authors: Xiaoling Yu, Wen Zhang, Zhiping Zhao, Chengsong Ye, Shuyan Zhou, Shaogui Wu, Lifen Han, Zhaofang Han and Hanhui Ye

    Citation: BMC Genomics 2019 20:822

    Content type: Research article

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  41. At sexual maturity, the liver of laying hens undergoes many metabolic changes to support vitellogenesis. In published transcriptomic approaches, hundreds of genes were reported to be overexpressed in laying he...

    Authors: Audrey Gloux, Michel J. Duclos, Aurélien Brionne, Marie Bourin, Yves Nys and Sophie Réhault-Godbert

    Citation: BMC Genomics 2019 20:821

    Content type: Research article

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  42. The lucinid clam Loripes orbiculatus lives in a nutritional symbiosis with sulphur-oxidizing bacteria housed in its gills. Although our understanding of the lucinid endosymbiont physiology and metabolism has made...

    Authors: Benedict Yuen, Julia Polzin and Jillian M. Petersen

    Citation: BMC Genomics 2019 20:820

    Content type: Research article

    Published on:

  43. The brain plays a critical role in upstream regulation of processes central to mating effort, parental effort, and self-maintenance. For seasonally breeding animals, the brain is likely mediating trade-offs am...

    Authors: Alexandra B. Bentz, Douglas B. Rusch, Aaron Buechlein and Kimberly A. Rosvall

    Citation: BMC Genomics 2019 20:819

    Content type: Research article

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  45. Internode elongation is one of the most important traits in sugarcane because of its relation to crop productivity. Understanding the microRNA (miRNA) and mRNA expression profiles related to sugarcane internod...

    Authors: Lihang Qiu, Rongfa Chen, Yegeng Fan, Xing Huang, Hanmin Luo, Faqian Xiong, Junxian Liu, Ronghua Zhang, Jingchao Lei, Huiwen Zhou, Jianming Wu and Yangrui Li

    Citation: BMC Genomics 2019 20:817

    Content type: Research article

    Published on:

  46. The Djallonke sheep is well adapted to harsh environmental conditions, and is relatively resistant to Haemonchosis and resilient to animal trypanosomiasis. The larger Sahelian sheep, which cohabit the same reg...

    Authors: M. Yaro, K. A. Munyard, E. Morgan, R. J. N. Allcock, M. J. Stear and D. M. Groth

    Citation: BMC Genomics 2019 20:816

    Content type: Research article

    Published on:

  47. The study of the mechanisms controlling wound healing is an attractive area within the field of biology, with it having a potentially significant impact on the health sector given the current medical burden as...

    Authors: Pavel Abaffy, Silvie Tomankova, Ravindra Naraine, Mikael Kubista and Radek Sindelka

    Citation: BMC Genomics 2019 20:815

    Content type: Research article

    Published on:

  48. Nsa cytoplasmic male sterility (CMS) is a novel alloplasmic male sterility system derived from somatic hybridization between Brassica napus and Sinapis arvensis. Identification of the CMS-associated gene is a pre...

    Authors: Shi-Fei Sang, De-Sheng Mei, Jia Liu, Qamar U. Zaman, Hai-Yan Zhang, Meng-Yu Hao, Li Fu, Hui Wang, Hong-Tao Cheng and Qiong Hu

    Citation: BMC Genomics 2019 20:813

    Content type: Research article

    Published on:

  49. Drought stress is a major limiting factor of soybean [Glycine max (L.) Merr.] production around the world. Soybean plants can ameliorate this stress with improved water-saving, sustained N2 fixation during water ...

    Authors: Clinton J. Steketee, Thomas R. Sinclair, Mandeep K. Riar, William T. Schapaugh and Zenglu Li

    Citation: BMC Genomics 2019 20:811

    Content type: Research article

    Published on:

  50. Resistance genes composing the two-layer immune system of plants are thought as important markers for breeding pathogen-resistant crops. Many have been the attempts to establish relationships between the genom...

    Authors: Hugo V. S. Rody, Renato G. H. Bombardelli, Silvana Creste, Luís E. A. Camargo, Marie-Anne Van Sluys and Claudia B. Monteiro-Vitorello

    Citation: BMC Genomics 2019 20:809

    Content type: Research article

    Published on:

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