Analysis of yeast genes conferring arsenite and cadmium tolerance. (A) Venn diagram visualizing unique and common As and Cd sensitive yeast mutants identified in this work. (B) Model showing selected functional categories (according to FunCats (MIPS)) that are affected by As and Cd. Yellow: function required for both As and Cd tolerance; Red: function required for As tolerance; Blue: function required for Cd tolerance. (C) Heat map depicting all functional categories in our data set that were significantly (p-value < 0.005) enriched for As and Cd sensitive mutants. Parent terms are in capitals, child terms in lower case letters. The colour indicates the fold enrichment of genes within individual categories. Gray boxes indicate a category that did not pass the significance (p-value < 0.005) cut-off.