Table 5 Log odd scores (LOS) of amino acid substitutions calculated using the Eqn (ii).

Mesophiles

Tiny (T)

1.47

1.12

-0.68

-3.86

0.79

-0.94

-3.31

-5.40

-1.32

0.87

-3.67

0.74

Small (S)

1.89

1.12

-0.59

-3.93

0.58

-0.86

-2.03

-4.96

-0.48

1.11

-2.41

0.44

Aliphatic (Al)

3.34

1.60

-0.40

-3.19

-0.29

-0.10

-2.60

-2.66

-2.50

2.69

-2.52

-0.33

Aromatic(Ar)

4.67

2.75

0.05

-0.40

-0.02

0.12

-0.41

-0.32

-0.73

1.94

-2.05

-0.11

Nonpolar (Np)

2.01

1.31

-0.49

-1.49

0.07

-1.01

-2.91

-3.93

-1.61

1.36

-3.31

-0.08

Polar (P)

3.50

2.03

0.59

-2.66

1.65

-0.84

-1.66

-2.55

-0.76

1.44

-1.91

1.51

Charged (C)

5.52

2.49

0.68

-2.40

1.69

-1.13

-1.54

-2.24

-0.83

1.69

-1.87

1.69

Basic (B)

5.75

3.44

0.47

-2.07

1.15

-1.16

-1.72

-1.76

-1.50

1.56

-2.07

0.89

Acidic (A)

5.29

1.94

1.00

-3.59

2.39

-1.10

-1.36

-4.84

-0.70

1.86

-1.68

2.84

Neutral (N)

1.78

1.39

0.16

-2.12

1.02

-0.69

-2.26

-3.11

-1.10

0.95

-2.68

0.98

H-philic (Hi)

5.53

2.41

0.97

-3.90

2.14

-1.07

-1.64

-2.66

-0.72

1.76

-1.78

2.17

H-phobic (Hb)

2.38

1.55

-0.48

-1.32

-0.08

-0.57

-2.57

-2.98

-1.98

1.97

-2.90

-0.14

All

2.56

1.60

-0.34

-1.89

0.42

-0.91

-1.83

-2.79

-0.87

1.34

-2.16

0.25