Figure 5

A, tissue from the normal looking contralateral hemisphere showed no observable staining of Tie-2 (arrows; × 40). B, stroked brain tissue showing many microvessels strongly staining positive for Tie-2 (i; × 40) and (ii and iii) at higher magnification (× 100; arrows). C, small microvessels from the peri-infarcted zone positive for Tie-2 (× 100). Di-iii, double immunoflourescence showing co-localization of Tie-2 (red) and CD105 (green) in peri-infarcted stroke tissue (× 100; sections from I06232 were used).