Prediction of disease-related mutations affecting protein localization

BMC Genomics

Table 2 Prediction results for the localization of wild type proteins with the Scandinavian protocol.

Compartment^a	tp	fp	tn	fn	Accuracy	Precision	Recall	MCC	Proteins located
Mtm	10	29	1337	140	0.889	0.256	0.067	0.086	39
Mps	0	6	1363	147	0.899	0.000	0.000	-0.021	6
Mma	91	74	1293	58	0.913	0.552	0.611	0.532	165
Gtm	23	178	1240	75	0.833	0.114	0.235	0.079	201
PM	221	35	619	641	0.554	0.863	0.256	0.268	256
S	246	84	1093	93	0.883	0.745	0.726	0.661	330
ER	2	1	1330	183	0.879	0.667	0.011	0.074	3
N	98	23	1097	298	0.788	0.810	0.247	0.368	121
P	6	24	1462	24	0.968	0.200	0.200	0.184	30
C	269	166	852	229	0.739	0.618	0.540	0.392	435
Summary	966^b	620^b		1888^b	0.835^c	0.483^c	0.289^c	0.262^c	1586^b

Abbreviations for statistical parameters as in Table 1.
^a C, cytosol; Gtm, Golgi, transmembrane; Mma, mitochondrial matrix; Mps, mitochondrial, periplasmic space; Mtm, mitochondrial transmembrane; N, nuclear; P, peroxisomal; PM, plasma membrane; S, secreted
^btotal number
^caverage value.

ISSN: 1471-2164