BMC Genomics

Table 3 Prediction results for the localization of wild type proteins with WoLF PSORT.

From: Prediction of disease-related mutations affecting protein localization

	Mutant compartment
Wild type compartment^a	tp	fp	tn	fn	Accuracy	Precision	Recall	MCC	Proteins located
CK	2	38	1471	5	0.972	0.050	0.286	0.110	40
CK_PM	0	31	1485	31	0.960	0.000	0.000	-0.020	31
C	339	304	713	160	0.694	0.527	0.679	0.362	643
C_G	0	29	1450	37	0.956	0.000	0.000	-0.022	29
C_M	8	145	1328	35	0.881	0.052	0.186	0.048	153
C_N	102	365	963	86	0.703	0.218	0.543	0.191	467
C_P	3	77	1425	11	0.942	0.038	0.214	0.070	80
ER	85	253	1081	97	0.769	0.251	0.467	0.217	338
ER_G	4	70	1392	50	0.921	0.054	0.074	0.023	74
ER_M	2	92	1413	9	0.933	0.021	0.182	0.042	94
S	281	321	856	58	0.750	0.467	0.829	0.474	602
S_PM	4	148	1358	6	0.898	0.026	0.400	0.081	152
G	13	74	1344	85	0.895	0.149	0.133	0.085	87
L	33	202	1258	23	0.852	0.140	0.589	0.235	235
M	128	325	1038	25	0.769	0.283	0.837	0.394	453
M_N	0	33	1459	24	0.962	0.000	0.000	-0.019	33
M_P	1	112	1397	6	0.922	0.009	0.143	0.018	113
N	325	330	790	71	0.735	0.496	0.821	0.467	655
P	12	302	1184	18	0.789	0.038	0.400	0.068	314
PM	356	185	841	134	0.790	0.658	0.727	0.533	542
Summary	1696^b	3398^b		966^b	0.854^c	0.174^c	0.375^c	0.168^c	5095^b

Abbreviations for statistical parameters as in Table 1.
^aC, cytosol; CK, cytoskeleton; G, Golgi compartment; M, mitochondrial; N, nuclear; P, peroxisomal; PM, plasma membrane; S, secreted
^btotal number. Underline sign indicates multiple predictions.
^caverage value

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