Skip to main content

Table 5 Changes in WoLF PSORT localization prediction due to mutations.

From: Prediction of disease-related mutations affecting protein localization

 

Mutant compartment

Wild type compartmenta

PM

S

S_PM

C

C_N

C_M

N

N/C_N

N/C/

C_N

ER

ER_

M

M

M_N

M_N/

C_M

P

L

CK

Total

P

 

2/2

0/1

1/6

  

2/2

  

0/1

 

0/6

  

1/1

  

6/19

S

0/1

   

0/4

 

0/1

  

4/5

1/1

4/9

   

0/2

 

9/23

S/S_PM

         

0/1

       

0/1

C

0/6

2/3

 

3/9

 

3/3

5/6

0/1

   

3/6

    

2/2

18/36

C/C_N

      

1/1

          

1/1

C_N

 

0/2

 

18/19

  

4/8

    

2/2

2/2

3/3

   

29/36

C_M

   

1/1

             

1/1

N

0/1

0/10

 

6/10

7/7

      

2/4

     

15/32

G/ER_G

               

0/1

 

0/1

ER

0/11

0/1

 

1/1

       

0/1

  

2/2

  

3/16

M

0/2

3/3

 

6/6

  

0/2

0/2

         

9/15

ER_M

   

1/1

             

1/1

M/P/M_P

        

0/1

        

0/1

Total

0/21

7/21

0/1

37/53

7/11

3/3

12/20

0/3

0/1

4/7

1/1

11/28

2/2

3/3

3/3

0/3

2/2

92/183

  1. The numbers separated by the slash sign are for how many proteins the wild type localization have been correctly predicted, and the number of analyzed mutations, respectively.
  2. aC, cytosol; CK, cytoskeleton; G, Golgi compartment; M, mitochondrial; N, nuclear; P, peroxisomal; PM, plasma membrane; S, secreted. Slash sign indicates alternative localization predictions and underline sign multiple predicted localizations.
Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us