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Table 3 Pathway enrichment of the up- and downregulated genes based on the KEGG database analysis

From: Transcription and splicing regulation in human umbilical vein endothelial cells under hypoxic stress conditions by exon array

Term Count % P-value
Upregulated pathways    
   HSA04010: MAPK signaling pathway 11 3.70% 7.4E-03
   HSA03050: Proteasome 7 2.36% 1.0E-05
   HSA04612: Antigen processing and presentation 6 2.02% 6.2E-03
Downregulated pathways    
   HSA04510: Focal adhesion 37 2.90% 5.4E-05
   HSA04810: Regulation of actin cytoskeleton 30 2.35% 6.4E-03
   HSA04110: Cell cycle 29 2.27% 1.2E-07
   HSA00240: Pyrimidine metabolism 18 1.41% 2.9E-03
   HSA04350: TGF-beta signaling pathway 17 1.33% 2.1E-03