Table 3 Pathway enrichment of the up- and downregulated genes based on the KEGG database analysis
Term | Count | % | P-value |
|---|---|---|---|
Upregulated pathways | Â | Â | Â |
   HSA04010: MAPK signaling pathway | 11 | 3.70% | 7.4E-03 |
   HSA03050: Proteasome | 7 | 2.36% | 1.0E-05 |
   HSA04612: Antigen processing and presentation | 6 | 2.02% | 6.2E-03 |
Downregulated pathways | Â | Â | Â |
   HSA04510: Focal adhesion | 37 | 2.90% | 5.4E-05 |
   HSA04810: Regulation of actin cytoskeleton | 30 | 2.35% | 6.4E-03 |
   HSA04110: Cell cycle | 29 | 2.27% | 1.2E-07 |
   HSA00240: Pyrimidine metabolism | 18 | 1.41% | 2.9E-03 |
   HSA04350: TGF-beta signaling pathway | 17 | 1.33% | 2.1E-03 |