Systematic Name | Common Name | Protein Description | Average log2 Fitness1 |
---|---|---|---|
YDR269C | Â | CCC2 antisense | -4.80 |
YER145C | FTR1 | High affinity iron permease that forms a complex with Fet3p, expression regulated by iron | -4.72 |
YNL259C | ATX1 | Cytosolic copper metallochaperone that transports copper to the secretory vesicle copper transporter Ccc2p for eventual insertion into Fet3p | -4.62 |
YPL170W | DAP1 | Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p, related to mammalian membrane progesterone receptors | -4.33 |
YDR455C | Â | Dubious open reading frame, overlaps with NHX1 | -4.30 |
YMR058W | FET3 | Ferro-O2-oxidoreductase required for high-affinity iron uptake | -3.85 |
YPL182C | Â | Dubious open reading frame, overlaps with CTI6 | -3.74 |
YPL181W | CTI6 | Relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter | -3.65 |
YJR040W | GEF1 | Chloride channel localized to late- or post-Golgi vesicles, involved in iron metabolism | -3.65 |
YKR052C | MRS4 | Mitochondrial iron transporter that functions under low-iron conditions | -3.55 |