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Table 3 Gene Ontology enrichment by biological process for differentially-expressed genes in BPS

From: Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae

BIOLOGICAL PROCESSES WITH UP-REGULATED GENES

Category

p-value1

#genes2

Category

p-value1

#genes2

Ion transport

1.00 E-14

20

Oxidation reduction

1.38 E-03

11

Iron ion transport

4.47 E-13

11

Metal ion transport

1.55 E-03

3

Copper ion import

2.37 E-06

4

Zinc ion transport

2.16 E-03

3

Siderophore transport

2.62 E-06

3

Siderophore-iron transport

2.78 E-03

2

Cellular iron ion homeostasis

9.36 E-05

6

Biopolymer biosynthetic process

2.87 E-03

7

Copper ion transport

1.17 E-04

4

Response to starvation

2.90 E-03

3

Intracellular copper ion transport

2.07 E-04

3

High-affinity iron ion transport

3.85 E-03

2

Transport

2.4 E-04

28

Cation transport

5.40 E-03

3

Response to inorganic substance

1.13 E-03

2

   

BIOLOGICAL PROCESSES WITH DOWN-REGULATED GENES

Category

p-value 1

# genes 2

Category

p-value 1

#genes 2

Tricarboxylic acid cycle

5.25 E-03

3

Regulation of ergosterol

6.36 E-03

1

   

biosynthetic process

  
  1. 1Calculated from hypergeometric distribution P < 0.01
  2. 2Number of identified genes in the Gene Ontology (GO) category
  3. Enriched categories were identified using Funspec; see Additional file 9 for complete tables.
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BMC Genomics

ISSN: 1471-2164

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