Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae

Table 5 List of iron homeostasis genes that are down-regulated in dap1Δ

Gene ID	Gene Name	Log₂ Expression¹	Protein function
YEL065W	ARN3	-0.77	Siderophore iron permease
YLR136C	TIS11/CTH1	-1.46	RNA binding protein involved in mRNA stability of genes encoding iron-containing proteins
YMR058W	FET3	-0.83	Cell surface ferroxidase, required for high-affinity ferrous iron uptake
YOL158C	ARN4	-1.29	Iron uptake via a siderophore enterobactin
YOR382W	FIT2	-2.33	Cell wall mannoprotein of iron transport facilitator
YOR383C	FIT3	-1.41	Cell wall mannoprotein of iron transport facilitator
YOR384W	FRE5	-0.81	Similar to Fre2p, ferric reductase

¹Expression data represents the average of differentially-expressed genes in at least three out of four independent experiments.
Gene expression profiling was performed in dap1Δ and wild type strain grown in YPD media.
See Additional file 12 for list of all differentially-expressed genes in dap1Δ.

ISSN: 1471-2164