Table 1 A list of 20 most regulated annotated genes during vitellogenesis and after E2 treatment of males.
| Â | Description | Symbol | GeneBank | Vit4/NV | Vit2/NV | E/M | Function according to http://www.ncbi.nlm.nih.gov/sites/entrez gene |
|---|---|---|---|---|---|---|---|
1 | Vitellogenin 3, phosvitinless | vtg3 | AF254638 | 103.3 | 94.5 | 125.7 | Egg yolk precursor, phosvitinless. |
2 | Similar to reticulon 1 | rtn1 | BI983061 | 75.5 | 88.5 | 79.3 | Associates with the endoplasmic reticulum. |
3 | Nothepsin, cathepsin e | nots | AJ278269 | 76.6 | 76.8 | 86.8 | Eukaryotic aspartyl (acid) protease. |
4 | Similar to low density lipoprotein receptor | ldlr | BF717943 | 28.3 | 28.2 | 136.3 | Plays a central role in cholesterol metabolism. |
5 | Moderately similar to spectrin repeat containing, nuclear envelope 1 | syne1 | AW019847 | 16.1 | 21.2 | 14.7 | Involved in cytoskeletal structure. |
6 | Similar to ectonucleoside triphosphate diphosphohydrolase 4 | entpd4 | AW344063 | 97 | 70.2 | 25.5 | Cleaving nucleotide tri- and diphosphates. |
7 | Similar to follistatin-like 1 | fstl1 | AI884233 | NS | NS | 3.2 | Play an important role in tissue specific regulation. |
8 | Similar to human Prefoldin subunit 6 | pfdn6 | BI891290 | 1.5 | NS | 3.7 | Binds and stabilizes newly synthesized polypeptides. |
9 | Lag1 homolog, ceramide synthase 2 | lass2 | AW171063 | 1.8 | NS | 4.5 | May play a role in the regulation of cell growth. |
10 | Ankyrin repeat domain 6 | ank | AF395113 | 12.3 | 10.3 | 4.3 | Ankyrin repeats mediate protein-protein interactions. |
11 | Similar to nitric oxide synthase interacting protein | nosip | AI545274 | 8.1 | 7.4 | 11.6 | Promotes translocation of eNOS from the plasma membrane to intracellular sites. |
12 | Similar to heterogeneous nuclear ribonucleoprotein h1 | hnrnph1 | AI497414 | 1.7 | NS | 2.8 | RNA recognition/binding motif. |
13 | Similar to family with sequence similarity 46 c | fam46c | AI959558 | 4.5 | 4.7 | 14 | The function of this gene is unknown. |
14 | Vitellogenin 1 | vtg1 | AF406784 | 7 | 6.3 | 28.6 | Egg yolk precursor. |
15 | Similar to human guanylate binding protein1 | gbp1 | BM181499 | 8.5 | 8.2 | 2.7 | Specifically bind guanine nucleotides (GMP, GDP, and GTP). |
16 | Similar to human protein fam20c precursor? | fam20c | BF717944 | 33.2 | 35.2 | 20.8 | Has a crucial role in normal bone development. |
17 | Similar to glutamate receptor, ionotropic, kainate 1 | grik1 | BM071695 | NS | NS | -16.4 | Ligand-gated ion channel. |
18 | Similar to lectin, mannose-binding, 1 precursor | lman1 | AW175541 | 4.8 | 4 | 6.6 | Mannose-specific lectin, a member of a Mannose-specific lectin, a member of a the secretory pathway of animal cells. |
19 | Similar to rna polymerase ii associated protein 1 | rpap1 | BM157210 | NS | NS | 2.4 | The function of this gene is unknown. |
20 | Estrogen receptor 1 | esr1 | AF349412 | 16 | 15.5 | 17 | A ligand-activated transcription factor. |