The evolution of isochore patterns in vertebrate genomes

BMC Genomics

Table 1 Relative amounts, average GC and average size of isochore families from vertebrates

Relative amount, %	L1	L2	H1	H2	H3
Human	19.0	37.0	31.0	11.0	3.0
Chimp	22.6	36.6	25.4	13.2	2.1
Dog	23.8	35.5	23.7	13.4	3.6
Overall average	21.8	36.4	26.7	12.5	2.9
Standard deviation	2.5	0.8	3.8	1.3	0.8
Chicken	17.4	38.5	30.3	12.0	(1.6)^a
Overall average	20.7	36.9	27.6	12.4	2.9
Standard deviation	3.0	1.2	3.6	1.1	0.8
Mouse	9.7	40.3	35.5	14.2	0.2
Opossum	49.2	37.9	10.0	2.3
Platypus	---	14.5	71.8	15.1	0.14
Zebrafish	75.7	23.3	---	---	---
Medaka	---	71.0	23.7	---	---
Stickleback	---	---	77.5	21.0	---
Pufferfish	---	---	55.3	37.8	---
Average GC
Human	36.0	38.9	43.1	48.7	54.5
Chimp	36.0	38.9	43.2	48.6	55.0
Dog	35.9	38.9	43.2	48.7	55.8
Mouse ^(b)	36.5	39.4	43.6	48.1	54.4
Platypus	---	40.0	42.9	47.9	54.9
Opossum	36.0	38.5	42.9	48.6	55.6
Chicken	36.6	39.3	43.4	48.8	54.7
Zebrafish	36.0	38.2	---	---	---
Medaka	---	39.9	42.3	---	---
Stickleback	---	---	44.2	47.3	---
Pufferfish	---	---	44.4	48.2	54.7
Overall average	36.2	39.1	43.3	48.3	54.8
Standard deviation	0.3	0.6	0.7	0.5	0.5
Average size (Mb)
Human	0.90	0.90	0.80	0.70	0.70
Chimp	(1.4)^b	0.80	0.60	0.70	0.60
Dog	1.02	0.69	0.53	0.55	0.59
Mouse	1.09	1.40	0.99	0.97	0.30
Opossum	(1.6)^b	0.80	0.60	0.50	0.40
Platypus	---	0.90	1.10	0.50	---
Chicken	0.70	0.81	0.60	0.55	(0.34)^(a)
Zebrafish	(1.9)^b	0.60	---	---	---
Medaka	---	(2.8)^b	0.90	---	---
Stickleback	---	---	(2.1)^b	0.70	---
Pufferfish	---	---	0.90	0.70	---

^(a) These values concern only a small part of H3 (for more details see ref. 7)
They were not included in calculating the standard deviation in A.
^(b) Values in parenthesis are likely to be at least in part artefactually large.

ISSN: 1471-2164