Figure 3

Homologous synteny blocks in cattle and human. Details about human homologs identified for RH-mapped markers used in this study. To the left, the BoLA RH-mapped markers are presented in their homologous HLA positions, with the corresponding megabase position of the human homolog listed to the right. Brackets indicate markers clustered by the RH analysis. These clustered markers have been assigned to the same cR position and therefore can be flipped with equal likelihood; as a result, caution should be exercised when considering these markers as part of an inversion. To the right, arrows indicate locations and orientations of homologous synteny blocks in relation to human, determined by this study, [14], and [29]. Proposed extensions of HSBs are represented as lighter-colored blocks with dotted edges; orientation is indicated by arrows within the blocks.