A. SMARCAL1 helicase C-terminal domain in phylogenetic tree with the highest parsimony (length = 52). The consistency index is 0.86, the retention index is 0.81, and the composite index is 0.77 for all sites. There were a total of 78 positions in the final dataset, out of which 11 were parsimony informative. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test (500 replicates) is shown next to the branches. B. Multiple sequence alignment of the helicase C-terminal domain in SMARCAL1. Highlighted regions show where the substitutions occur.