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Table 3 Lowest level GO terms that differed in QTL regions compared to the genome as a whole.

From: QTL global meta-analysis: are trait determining genes clustered?

GO Term Description Population Frequency QTL/Population p-value
Body Conformation
GO:0005254 chloride channel activity 0.00115 8.29 2.89E-04
GO:0030594 neurotransmitter receptor activity 0.00159 8.39 1.61E-05
GO:0048500 signal recognition particle 0.00040 14.38 9.38E-04
GO:0004890 GABA-A receptor activity 0.00102 11.25 1.09E-05
GO:0005230 extracellular ligand-gated ion channel activity 0.00159 9.58 1.35E-06
GO:0007214 gamma-aminobutyric acid signaling pathway 0.00111 8.63 2.38E-04
GO:0045202 synapse 0.00766 2.99 7.42E-04
GO:0045211 postsynaptic membrane 0.00394 4.36 2.22E-04
Carcass
GO:0050806 positive regulation of synaptic transmission 0.00031 3.38 2.00E-04
GO:0016600 flotillin complex 0.00031 3.38 2.00E-04
GO:0051059 NF-kappaB binding 0.00088 2.36 2.24E-04
GO:0006986 response to unfolded protein 0.00208 1.87 2.07E-04
Disease Resistance
GO:0046785 microtubule polymerization 0.00035 15.50 5.33E-06
GO:0031116 positive regulation of microtubule polymerization 0.00035 15.50 5.33E-06
GO:0009925 basal plasma membrane 0.00049 13.53 1.64E-06
GO:0001937 negative regulation of endothelial cell proliferation 0.00044 12.40 2.24E-05
GO:0007154 cell communication 0.00389 3.38 2.10E-04
GO:0042493 response to drug 0.00195 4.51 3.30E-04
GO:0004620 phospholipase activity 0.00022 19.85 1.27E-05
GO:0019900 kinase binding 0.00058 9.54 1.03E-04
GO:0042470 melanosome 0.00049 9.02 6.90E-04
GO:0043434 response to peptide hormone stimulus 0.00084 6.53 7.63E-04
GO:0030659 cytoplasmic vesicle membrane 0.00035 12.40 1.61E-04
GO:0016599 caveola 0.00053 10.34 6.58E-05
GO:0019905 syntaxin binding 0.00058 9.54 1.03E-04
GO:0009395 phospholipid catabolic process 0.00031 14.18 8.33E-05
GO:0050998 nitric-oxide synthase binding 0.00035 15.50 5.33E-06
GO:0030321 transepithelial chloride transport 0.00031 14.18 8.33E-05
GO:0042311 vasodilation 0.00040 11.03 2.81E-04
GO:0019861 flagellum 0.00111 5.95 3.87E-04
GO:0007595 lactation 0.00084 6.53 7.63E-04
GO:0030317 sperm motility 0.00084 7.83 7.29E-05
Fat
GO:0051059 NF-kappaB binding 0.00088 2.33 1.06E-04
GO:0006986 response to unfolded protein 0.00208 1.85 1.01E-04
Growth
GO:0007586 digestion 0.00133 2.79 2.66E-04
Milk Protein
GO:0050785 advanced glycation end-product receptor activity 0.00027 4.67 9.67E-05
GO:0051059 NF-kappaB binding 0.00088 3.27 4.36E-06
GO:0006986 response to unfolded protein 0.00208 2.28 2.71E-05
GO:0007584 response to nutrient 0.00217 2.19 6.25E-05
Milk Yield
GO:0005922 connexon complex 0.00080 3.31 2.05E-04
GO:0030375 thyroid hormone receptor coactivator activity 0.00040 4.64 9.74E-05
GO:0042809 vitamin D receptor binding 0.00071 3.35 3.82E-04
GO:0042974 retinoic acid receptor binding 0.00031 5.96 3.71E-06
GO:0004886 retinoid-X receptor activity 0.00044 4.77 2.03E-05
Reproduction
GO:0005882 intermediate filament 0.00186 3.16 1.38E-06
  1. The table describes fine detail GO terms found to be significantly over represented through hypergeometric analysis. In bold are the QTL categories from which the subsequent terms were found to be in abundance. Population frequency describes the frequency of the occurrence of the GO code genome wide. QTL/Population describes the ratio of the frequency of a GO code within a QTL region compared to the frequency of that GO code genome wide.