Table 3 Lowest level GO terms that differed in QTL regions compared to the genome as a whole.
From: QTL global meta-analysis: are trait determining genes clustered?
GO Term | Description | Population Frequency | QTL/Population | p-value |
|---|---|---|---|---|
Body Conformation | ||||
GO:0005254 | chloride channel activity | 0.00115 | 8.29 | 2.89E-04 |
GO:0030594 | neurotransmitter receptor activity | 0.00159 | 8.39 | 1.61E-05 |
GO:0048500 | signal recognition particle | 0.00040 | 14.38 | 9.38E-04 |
GO:0004890 | GABA-A receptor activity | 0.00102 | 11.25 | 1.09E-05 |
GO:0005230 | extracellular ligand-gated ion channel activity | 0.00159 | 9.58 | 1.35E-06 |
GO:0007214 | gamma-aminobutyric acid signaling pathway | 0.00111 | 8.63 | 2.38E-04 |
GO:0045202 | synapse | 0.00766 | 2.99 | 7.42E-04 |
GO:0045211 | postsynaptic membrane | 0.00394 | 4.36 | 2.22E-04 |
Carcass | ||||
GO:0050806 | positive regulation of synaptic transmission | 0.00031 | 3.38 | 2.00E-04 |
GO:0016600 | flotillin complex | 0.00031 | 3.38 | 2.00E-04 |
GO:0051059 | NF-kappaB binding | 0.00088 | 2.36 | 2.24E-04 |
GO:0006986 | response to unfolded protein | 0.00208 | 1.87 | 2.07E-04 |
Disease Resistance | ||||
GO:0046785 | microtubule polymerization | 0.00035 | 15.50 | 5.33E-06 |
GO:0031116 | positive regulation of microtubule polymerization | 0.00035 | 15.50 | 5.33E-06 |
GO:0009925 | basal plasma membrane | 0.00049 | 13.53 | 1.64E-06 |
GO:0001937 | negative regulation of endothelial cell proliferation | 0.00044 | 12.40 | 2.24E-05 |
GO:0007154 | cell communication | 0.00389 | 3.38 | 2.10E-04 |
GO:0042493 | response to drug | 0.00195 | 4.51 | 3.30E-04 |
GO:0004620 | phospholipase activity | 0.00022 | 19.85 | 1.27E-05 |
GO:0019900 | kinase binding | 0.00058 | 9.54 | 1.03E-04 |
GO:0042470 | melanosome | 0.00049 | 9.02 | 6.90E-04 |
GO:0043434 | response to peptide hormone stimulus | 0.00084 | 6.53 | 7.63E-04 |
GO:0030659 | cytoplasmic vesicle membrane | 0.00035 | 12.40 | 1.61E-04 |
GO:0016599 | caveola | 0.00053 | 10.34 | 6.58E-05 |
GO:0019905 | syntaxin binding | 0.00058 | 9.54 | 1.03E-04 |
GO:0009395 | phospholipid catabolic process | 0.00031 | 14.18 | 8.33E-05 |
GO:0050998 | nitric-oxide synthase binding | 0.00035 | 15.50 | 5.33E-06 |
GO:0030321 | transepithelial chloride transport | 0.00031 | 14.18 | 8.33E-05 |
GO:0042311 | vasodilation | 0.00040 | 11.03 | 2.81E-04 |
GO:0019861 | flagellum | 0.00111 | 5.95 | 3.87E-04 |
GO:0007595 | lactation | 0.00084 | 6.53 | 7.63E-04 |
GO:0030317 | sperm motility | 0.00084 | 7.83 | 7.29E-05 |
Fat | ||||
GO:0051059 | NF-kappaB binding | 0.00088 | 2.33 | 1.06E-04 |
GO:0006986 | response to unfolded protein | 0.00208 | 1.85 | 1.01E-04 |
Growth | ||||
GO:0007586 | digestion | 0.00133 | 2.79 | 2.66E-04 |
Milk Protein | ||||
GO:0050785 | advanced glycation end-product receptor activity | 0.00027 | 4.67 | 9.67E-05 |
GO:0051059 | NF-kappaB binding | 0.00088 | 3.27 | 4.36E-06 |
GO:0006986 | response to unfolded protein | 0.00208 | 2.28 | 2.71E-05 |
GO:0007584 | response to nutrient | 0.00217 | 2.19 | 6.25E-05 |
Milk Yield | ||||
GO:0005922 | connexon complex | 0.00080 | 3.31 | 2.05E-04 |
GO:0030375 | thyroid hormone receptor coactivator activity | 0.00040 | 4.64 | 9.74E-05 |
GO:0042809 | vitamin D receptor binding | 0.00071 | 3.35 | 3.82E-04 |
GO:0042974 | retinoic acid receptor binding | 0.00031 | 5.96 | 3.71E-06 |
GO:0004886 | retinoid-X receptor activity | 0.00044 | 4.77 | 2.03E-05 |
Reproduction | ||||
GO:0005882 | intermediate filament | 0.00186 | 3.16 | 1.38E-06 |