Figure 2

Genomic organisation of the genes in the bovine TRB locus as described in Btau_3.1. The order and location of TRB genes on (A) Chr4.003.105 (B) Chr.4.003.108_RC and (C) ChrUn.003.1717. Red dotted lines represent large regions of undetermined sequence within the scaffolds. TRBV genes are classified as functional (green), open-reading frame non-functional (orange) or pseudogenes (red), and their transcriptional orientation indicated by their direction; TRBV gene 'relics' are shown as open boxes. TRBD (blue vertical lines), TRBJ (pink vertical lines) and TRBC (yellow boxes) genes are arranged into 3 DJC clusters, with a putative bovine TRB enhancer (Eβ) located 3' to the TRBC3 gene (black diagonal shading). The sizes of non TRB genes (black boxes) – dopamine-β-hydroxylase-like gene (DβH-like) and trypsinogen genes (T) are not shown to scale. Regions of duplicated DNA are indicated by the colour-coordinated boxes located beneath the scheme of gene location. Broken lines indicate regions of DNA that are not present in all copies of the duplicated region.