Gene expression profile of bladder tissue of patients with ulcerative interstitial cystitis

BMC Genomics

Table 2 Top 25 gene expressions in ulcerative IC

#	gene symbol*	protein	protein name	over-expression$
1	CHI3L1	CH3L1_HUMAN	Chitinase-3-like protein 1	68
2	CXCL13	CXL13_HUMAN	C-X-C motif chemokine 13	59
3	CR2, CD21[22]	CR2_HUMAN	Complement receptor type 2	47
4	LTF	TRFL_HUMAN	Lactotransferrin	44
5	IGHM[23]	IGHM_HUMAN	Ig mu chain C region	37
6	MS4A1[24]	CD20_HUMAN	B-lymphocyte antigen CD20	32
7	IGHG1[25]	IGHG1_HUMAN	Ig gamma-1 chain C region	26
8	IGL@[26]	IGL@	immunoglobulin lambda locus	24
9	CCL18	CCL18_HUMAN	C-C motif chemokine 18	23
10	FCRLA[27]	FCRLA_HUMAN	Fc receptor-like A	22
11	IGH@[25]	IGH@	immunoglobulin heavy locus	21
12	MGC29506	PACAP_HUMAN	Proapoptotic caspase adapter protein	20
13	FCRL5[28]	FCRL5_HUMAN	Fc receptor-like protein 5	20
14	IGHA1[25]	IGHA1_HUMAN	Ig alpha-1 chain C region	19
15	PAX5[29]	PAX5_HUMAN	Paired box protein Pax-5	19
16	FCRL3[28]	FCRL3_HUMAN	Fc receptor-like protein 3	19
17	BLK[30]	BLK_HUMAN	Tyrosine-protein kinase BLK	19
18	NTN2L	NET2_HUMAN	Netrin-2-like protein	18
19	TDO2	T23O_HUMAN	Tryptophan 2,3-dioxygenase	18
20	CLC	LPPL_HUMAN	Eosinophil lysophospholipase	16
21	IGHV1–69[31]	IGHV1–69	immunoglobulin heavy variable 1–69	16
22	RPL14	RL14_HUMAN	60S ribosomal protein L14	16
23	FCRL1[28]	FCRL1_HUMAN	Fc receptor-like protein 1	16
24	AQP9	AQP9_HUMAN	Aquaporin-9	15
25	IL8	IL8_HUMAN	Interleukin-8	15

ISSN: 1471-2164