Figure 2

A cluster of 11 serpin (S) genes (S1-to-11) spanning 170 kb of DNA sequence. Structurally, nine serpin genes, S1-to-9 have introns, while S10 and 11 are intronless. When scanned against the whole genome shotgun DNA sequence database, encoding these open reading frames of these genes are ABJB010004033 for S1, ABJB010065261 for S2, ABJB010418850, ABJB011135496, ABJB0109755250 and ABJB010321224 for S3, ABJB011011198 for S4, ABJB010283366 for S5, ABJB011103238 and ABJB010459188 for S6, ABJB010459188 for S7, ABJB010459188 for S8 and ABJB010543279 for S9, 10 and 11. Based on genomic DNA sequence, complete open reading frames (ORF) were detected for all serpins except for S11 and S6, which are partial and their ORFs were assembled from EST sequences indicated in Table 3. Open arrow heads (⇐) denote intronless, closed arrow heads (⇒) denote intron-containing genes.