Figure 7
From: Correlation of expression profiles between microRNAs and mRNA targets using NCI-60 data
The density plot of the correlation coefficients computed using miRNA-mRNA pairs predicted by TargetScanS and then filtered by GenMiR++. The algorithm GenMiR++ provides a scoring system that determines the confidence level of the miRNA-mRNA interactions predicted by TargetScanS. There are three such levels: the high-confidence, the low-confidence and the unsupported. Using NCI-60 data, the distributions of Pearson correlation coefficients for the four categories specified by GenMiR++ (all, high-confidence, low-confidence and unsupported) are shown here. Only those correlations presenting Benjamini/Hochberg-corrected p-values < 0.05 are included. There are 412 such correlations in "All", 80 in "High-confidence", 41 in "Low-confidence" and 291 in "Unsupported".