A Plasmodium falciparum FcB1-schizont-EST collection providing clues to schizont specific gene structure and polymorphism

Table 1 Summary of the FcB1-schizont-EST distribution on the 14 P. falciparum chromosomes.

Chromosome (a)	Matched ESTs (b)	ESTs in protein coding genes (c)	ESTs in ribosomal loci (d)	ESTs in telomeric loci (e)	Protein coding genes identified (f)	Functionaly annotated protein coding genes (g)	Putative protein coding gene (h)	Hypothetical protein coding gene (i)	Confirmation of gene model (j)	Modification of gene model (k)	Evidence for protein polymorphism (l)
1	991	365	626	0	5	3	0	2	1	1	1
2	937	937	0	0	15	4	6	5	4	1	0
3	430	430	0	0	13	2	5	6	2	0	0
4	137	137	0	0	8	2	3	3	1	0	1
5	10,174	292	9,846	36	15	1	5	9	2	2	2
6	885	885	0	0	17	5	6	6	1	0	2
7	9,953	536	9,417	0	14	3	4	7	3	0	2
8	337	332	2	3	11	2	6	3	2	1	1
9	905	905	0	0	16	4	5	7	2	2	0
10	636	634	0	2	21	8	4	9	3	2	5
11	653	653	0	0	17	4	2	11	1	1	0
12	1,011	1,011	0	0	25	9	3	13	4	1	2
13	994	958	0	36	32	8	6	18	2	2	3
14	1,179	1,179	0	0	34	5	7	22	1	1	2
Total	29,222	9,254	19,891	77	243	60	62	121	29	14	21
Unique	19,906	9,254	10,611	41	243	30	62	121	29	14	21
%		46.5	53.3	0.2		25	25	50	12	6	9

This table lists the number of FcB1-schizont-ESTs (b) mapped on each of the 14 P. falciparum chromosomes (a), detailing those matching protein coding genes (c), ribosomal loci (d) or telomeric loci (e). The number of protein coding genes covered by the FcB1-schizont-ESTs is indicated in (f), (g, h, i) detailing whether these genes are functionnaly annotated genes (g), putative genes (h) or hypothetical genes (i). Columns (j, k, l) indicate the number of gene models that were confirmed (j), modified (k) or identified as displaying some strain dependent polymorphism between FcB1 and 3D7 (l) after analysis of 3D7-genomic versus FcB1-EST alignments. "Total" corresponds to the total number of cases for the 14 chromosomes, "Unique" accounts for the fact that many ribosomal-RNA-matching ESTs matched both chromosomes 5 and 7 and that the 36 ESTs matching the telomeric end of chromosome 5 also matched the telomeric end of chromosome 13.

ISSN: 1471-2164