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Table 6 Major known genes by functional class in the L3c gene set

From: Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3

Function class

Gene

oligo ID

Fold

NCBI accession number and description

protein synthesis

    
 

rRNA promoter binding (1)

BMC10335

4.6

NP_671477.1| rRNA promoter binding protein

 

RNA binding (3)

BMC04564

2.5

AAC47624.1| putative RNA binding protein

 

Elongation Factor (5)

AA842168

4.7

CAB40840.1| elongation factor 1 beta

 

rps or rpl ((38)

BMC00849

4.6

AAN05602.1| ribosomal protein S7

 

Zinc finger (8)

14287.m00022

9.7

P_698623.1| PREDICTED: similar to zinc finger

 

hsp(1)

13293.m00125

9.5

AAY66912.1| putative heat shock-related protein

 

Pin1 (2)

AA109462

6.5

AAD01597.1| peptidyl-prolyl cis-trans isomerase

cell cycle

    
 

mab-21 (1)

BMC02725

4.5

NP_497940.2| Male ABnormal family member (mab-21)

 

tctp (Tph) (1)

BMC12076

2.9

AAK71499.1| translationally controlled tumor protein-like protein

 

Histone (7)

12698.m00329

13.5

P30757|H2B_SIPNU Histone H2B

 

Actin (1)

BMC06331

6

AAU94673.1| actin

 

Tubulin (3)

BMC01602

3.2

AAA27865.1| beta-tubulin

fiber growth

    
 

MSP fiber proteins (MFP) (2)

BMC01338

6.9

AAP94887.1| MFP3

  

BMC02125

3.7

AAP94885.1| MFP1-beta

development cell phagocytosis

sHSP (2)

15334.m00009

4.7

CAA61152.1| small heat shock protein

 

ced-2 (1)

14972.m07627

7.8

NP_500105.1| CEll Death abnormality family member (ced-2)

  1. Numbers in parentheses represent the number of oligos that match a particular gene that was upregulated.