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Table 5 Signal ratios of SNPs are independent from the chemical class (pyrimidine or purine) of the bases present in the probe and sample alleles.

From: Evaluation of a microarray-hybridization based method applicable for discovery of single nucleotide polymorphisms (SNPs) in the Pseudomonas aeruginosa genome

  PAO1 allele (probe)a PA14 allele (sample)a abundance median signal ratio sensitivityb
transitions Y Y 12315 -0.44 46.9%
  R R 12681 -0.43 45.8%
transversions R Y 3353 -0.44 46.9%
  Y R 3236 -0.37 43.0%
  Σ 31585 -0.43 45.9%
  1. a Y – IUPAC format for pyrimidine bases (C, T), R – purine bases (A, G).
  2. b determined for D th = -0.5.