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Table 2 GO biological processes that are regulated by 5 ng/L EE2

From: Gene expression responses in male fathead minnows exposed to binary mixtures of an estrogen and antiestrogen

UPREGULATED
GO ID GO Biological Process Fisher p Value # of Genes Selected # of Genes on Array
GO:0007275 development 4.35E-03 36 1250
GO:0040036 regulation of fibroblast growth factor receptor signaling 1.58E-02 2 9
GO:0016265 death 1.62E-02 3 27
GO:0018149 peptide cross-linking 1.88E-02 2 10
GO:0050777 negative regulation of immune response 1.88E-02 2 10
GO:0006955 immune response 1.93E-02 10 251
GO:0050776 regulation of immune response 2.09E-02 3 30
GO:0050727 regulation of inflammatory response 2.19E-02 2 11
GO:0006694 steroid biosynthesis 2.26E-02 3 31
GO:0006730 one-carbon compound metabolism 2.44E-02 3 32
GO:0008543 fibroblast growth factor receptor signaling pathway 2.53E-02 2 12
GO:0015758 glucose transport 2.53E-02 2 12
GO:0042770 DNA damage response, signal transduction 2.53E-02 2 12
GO:0008645 hexose transport 2.88E-02 2 13
GO:0015749 monosaccharide transport 2.88E-02 2 13
GO:0008284 positive regulation of cell proliferation 3.24E-02 3 36
GO:0019439 aromatic compound catabolism 3.26E-02 2 14
GO:0007154 cell communication 3.56E-02 41 1692
GO:0043281 regulation of caspase activity 3.65E-02 2 15
GO:0051241 negative regulation of organismal physiological process 3.65E-02 2 15
GO:0009611 response to wounding 3.73E-02 7 167
GO:0009607 response to biotic stimulus 3.91E-02 11 324
GO:0051707 response to other organism 4.03E-02 7 170
GO:0045596 negative regulation of cell differentiation 4.06E-02 2 16
GO:0009605 response to external stimulus 4.18E-02 8 209
GO:0051239 regulation of organismal physiological process 4.19E-02 4 69
GO:0051242 positive regulation of cellular physiological process 4.48E-02 5 103
GO:0006952 defense response 4.48E-02 10 291
GO:0019882 antigen presentation 4.92E-02 2 18
DOWNREGULATED
GO ID GO Name Fisher p Value # of Genes Selected # of Genes on Array
GO:0006260 DNA replication 9.27E-04 9 124
GO:0009314 response to radiation 1.51E-03 5 40
GO:0006280 mutagenesis 2.08E-03 2 2
GO:0006281 DNA repair 5.33E-03 9 163
GO:0009416 response to light stimulus 5.51E-03 4 34
GO:0006974 response to DNA damage stimulus 7.91E-03 9 174
GO:0006259 DNA metabolism 8.60E-03 17 458
GO:0009719 response to endogenous stimulus 9.05E-03 9 178
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1.29E-02 56 2183
GO:0007623 circadian rhythm 1.74E-02 2 9
GO:0018149 peptide cross-linking 2.07E-02 2 10
GO:0016339 calcium-dependent cell-cell adhesion 2.41E-02 2 11
GO:0006885 regulation of pH 2.78E-02 2 12
GO:0001775 cell activation 3.00E-02 3 33
GO:0045321 immune cell activation 3.00E-02 3 33
GO:0006508 proteolysis 3.17E-02 16 493
GO:0000245 spliceosome assembly 3.17E-02 2 13
GO:0046839 phospholipid dephosphorylation 3.17E-02 2 13
GO:0043283 biopolymer metabolism 3.56E-02 53 2167
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 3.65E-02 5 92
GO:0007156 homophilic cell adhesion 3.94E-02 4 64
GO:0006289 nucleotide-excision repair 4.00E-02 2 15
GO:0009266 response to temperature stimulus 4.00E-02 2 15
GO:0042471 ear morphogenesis 4.00E-02 2 15
GO:0050896 response to stimulus 4.50E-02 26 948
GO:0019941 modification-dependent protein catabolism 4.53E-02 5 98
GO:0043632 modification-dependent macromolecule catabolism 4.53E-02 5 98
GO:0009798 axis specification 4.91E-02 2 17
GO:0030258 lipid modification 4.91E-02 2 17
GO:0042110 T cell activation 4.91E-02 2 17