Table 2 GO biological processes that are regulated by 5 ng/L EE2
UPREGULATED | ||||
|---|---|---|---|---|
GO ID | GO Biological Process | Fisher p Value | # of Genes Selected | # of Genes on Array |
GO:0007275 | development | 4.35E-03 | 36 | 1250 |
GO:0040036 | regulation of fibroblast growth factor receptor signaling | 1.58E-02 | 2 | 9 |
GO:0016265 | death | 1.62E-02 | 3 | 27 |
GO:0018149 | peptide cross-linking | 1.88E-02 | 2 | 10 |
GO:0050777 | negative regulation of immune response | 1.88E-02 | 2 | 10 |
GO:0006955 | immune response | 1.93E-02 | 10 | 251 |
GO:0050776 | regulation of immune response | 2.09E-02 | 3 | 30 |
GO:0050727 | regulation of inflammatory response | 2.19E-02 | 2 | 11 |
GO:0006694 | steroid biosynthesis | 2.26E-02 | 3 | 31 |
GO:0006730 | one-carbon compound metabolism | 2.44E-02 | 3 | 32 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 2.53E-02 | 2 | 12 |
GO:0015758 | glucose transport | 2.53E-02 | 2 | 12 |
GO:0042770 | DNA damage response, signal transduction | 2.53E-02 | 2 | 12 |
GO:0008645 | hexose transport | 2.88E-02 | 2 | 13 |
GO:0015749 | monosaccharide transport | 2.88E-02 | 2 | 13 |
GO:0008284 | positive regulation of cell proliferation | 3.24E-02 | 3 | 36 |
GO:0019439 | aromatic compound catabolism | 3.26E-02 | 2 | 14 |
GO:0007154 | cell communication | 3.56E-02 | 41 | 1692 |
GO:0043281 | regulation of caspase activity | 3.65E-02 | 2 | 15 |
GO:0051241 | negative regulation of organismal physiological process | 3.65E-02 | 2 | 15 |
GO:0009611 | response to wounding | 3.73E-02 | 7 | 167 |
GO:0009607 | response to biotic stimulus | 3.91E-02 | 11 | 324 |
GO:0051707 | response to other organism | 4.03E-02 | 7 | 170 |
GO:0045596 | negative regulation of cell differentiation | 4.06E-02 | 2 | 16 |
GO:0009605 | response to external stimulus | 4.18E-02 | 8 | 209 |
GO:0051239 | regulation of organismal physiological process | 4.19E-02 | 4 | 69 |
GO:0051242 | positive regulation of cellular physiological process | 4.48E-02 | 5 | 103 |
GO:0006952 | defense response | 4.48E-02 | 10 | 291 |
GO:0019882 | antigen presentation | 4.92E-02 | 2 | 18 |
DOWNREGULATED | ||||
GO ID | GO Name | Fisher p Value | # of Genes Selected | # of Genes on Array |
GO:0006260 | DNA replication | 9.27E-04 | 9 | 124 |
GO:0009314 | response to radiation | 1.51E-03 | 5 | 40 |
GO:0006280 | mutagenesis | 2.08E-03 | 2 | 2 |
GO:0006281 | DNA repair | 5.33E-03 | 9 | 163 |
GO:0009416 | response to light stimulus | 5.51E-03 | 4 | 34 |
GO:0006974 | response to DNA damage stimulus | 7.91E-03 | 9 | 174 |
GO:0006259 | DNA metabolism | 8.60E-03 | 17 | 458 |
GO:0009719 | response to endogenous stimulus | 9.05E-03 | 9 | 178 |
GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolism | 1.29E-02 | 56 | 2183 |
GO:0007623 | circadian rhythm | 1.74E-02 | 2 | 9 |
GO:0018149 | peptide cross-linking | 2.07E-02 | 2 | 10 |
GO:0016339 | calcium-dependent cell-cell adhesion | 2.41E-02 | 2 | 11 |
GO:0006885 | regulation of pH | 2.78E-02 | 2 | 12 |
GO:0001775 | cell activation | 3.00E-02 | 3 | 33 |
GO:0045321 | immune cell activation | 3.00E-02 | 3 | 33 |
GO:0006508 | proteolysis | 3.17E-02 | 16 | 493 |
GO:0000245 | spliceosome assembly | 3.17E-02 | 2 | 13 |
GO:0046839 | phospholipid dephosphorylation | 3.17E-02 | 2 | 13 |
GO:0043283 | biopolymer metabolism | 3.56E-02 | 53 | 2167 |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 3.65E-02 | 5 | 92 |
GO:0007156 | homophilic cell adhesion | 3.94E-02 | 4 | 64 |
GO:0006289 | nucleotide-excision repair | 4.00E-02 | 2 | 15 |
GO:0009266 | response to temperature stimulus | 4.00E-02 | 2 | 15 |
GO:0042471 | ear morphogenesis | 4.00E-02 | 2 | 15 |
GO:0050896 | response to stimulus | 4.50E-02 | 26 | 948 |
GO:0019941 | modification-dependent protein catabolism | 4.53E-02 | 5 | 98 |
GO:0043632 | modification-dependent macromolecule catabolism | 4.53E-02 | 5 | 98 |
GO:0009798 | axis specification | 4.91E-02 | 2 | 17 |
GO:0030258 | lipid modification | 4.91E-02 | 2 | 17 |
GO:0042110 | T cell activation | 4.91E-02 | 2 | 17 |