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Table 6 Putative candidate genes in QTL regions

From: Microsatellite mapping of QTLs affecting resistance to coccidiosis (Eimeria tenella) in a Fayoumi × White Leghorn cross

QTL region candidate gene name description functional category example of activity
1-A BCL2L13 BCL2-like 13 (apoptosis facilitator) apoptosis regulated by TNFα, pro-inflammatory cytokine
  IL17RA interleukin 17 receptor A inflammatory response receptor of IL17, pro-inflammatory cytokine
1-B TNFRSF1A tumor necrosis factor receptor superfamily, member 1A inflammatory response receptor of TNFα, pro-inflammatory cytokine
1-C TLR7 toll-like receptor 7 inflammatory response, innate immunity recognizes pathogen-associated molecular patterns
2-A GRB10 growth factor receptor-bound protein 10 growth regulates IGF-1 signaling
  IKZF1 IKAROS family zinc finger 1 (Ikaros) immune response triggers CD4/CD8 commitment lineage
2-B ANKRD12 ankyrin repeat domain 12   regulated by CXCL12
3-B GHRL ghrelin/obestatin preprohormone growth regulates GH
3-C APOB apolipoprotein B (including Ag(x) antigen) lipid transport principal component of LDL
6-A CXCL12 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) inflammatory response, immune response activates leukocytes
6-B BLNK B-cell linker immune response role in B-cell function and development
23-A FABP3 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) lipid transport participates in uptake and transport of fatty acids
  C2 complement component 2 innate immune response part of complement system pathway