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Table 1 Enrichment analysis

From: In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach

Term Count % PValue
GO:0007275~multicellular organismal development 18 54.55% 0.000000
GO:0003700~transcription factor activity 12 36.36% 0.000000
GO:0009653~anatomical structure morphogenesis 16 48.48% 0.000000
GO:0032502~developmental process 20 60.61% 0.000000
GO:0009790~embryonic development 10 30.30% 0.000000
GO:0048856~anatomical structure development 17 51.52% 0.000000
GO:0030528~transcription regulator activity 13 39.39% 0.000002
GO:0030154~cell differentiation 15 45.45% 0.000002
GO:0048869~cellular developmental process 15 45.45% 0.000002
GO:0007389~pattern specification process 6 18.18% 0.000010
GO:0032501~multicellular organismal process 19 57.58% 0.000019
GO:0045165~cell fate commitment 5 15.15% 0.000022
GO:0043565~sequence-specific DNA binding 8 24.24% 0.000029
GO:0003677~DNA binding 14 42.42% 0.000051
GO:0031323~regulation of cellular metabolic process 16 48.48% 0.000063
GO:0019222~regulation of metabolic process 16 48.48% 0.000095
GO:0009887~organ morphogenesis 7 21.21% 0.000105
GO:0031325~positive regulation of cellular metabolic process 7 21.21% 0.000107
GO:0009893~positive regulation of metabolic process 7 21.21% 0.000154
GO:0001824~blastocyst development 3 9.09% 0.000356
GO:0045449~regulation of transcription 14 42.42% 0.000413
GO:0019219~regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 14 42.42% 0.000519
GO:0050789~regulation of biological process 19 57.58% 0.000533
GO:0065007~biological regulation 20 60.61% 0.000539
GO:0006350~transcription 14 42.42% 0.000597
GO:0009798~axis specification 3 9.09% 0.000640
GO:0050794~regulation of cellular process 18 54.55% 0.000754
GO:0010468~regulation of gene expression 14 42.42% 0.000756
GO:0006355~regulation of transcription, DNA-dependent 13 39.39% 0.000890
  1. Top enriched gene ontology categories for the 33 OCT4 target genes as received by DAVID [25] (see Additional file 2 for the complete results).