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Figure 1 | BMC Genomics

Figure 1

From: Exaptation of an ancient Alu short interspersed element provides a highly conserved vitamin D-mediated innate immune response in humans and primates

Figure 1

Conservation of the VDRE-containing AluSx SINEs in humans, apes, OWMs and NWMs. A) Amplification of the AluSx SINEs from a panel of non-human primates and humans. Products of the expected size were found in all but three primates. The increase in fragment sizes for M. mulatta, S. labiatus and C. jacchus was due to an additional Alu insertion. B) Schematic indicating the position and type of Alu insertion that was identified from sequencing the PCR products amplified in panel A. The location of the VDRE is indicated by the arrow. C) The nucleotide sequences of each AluSx SINE amplified in panel A were aligned with the AluSx consensus sequence [74]. The positions of the A- and B-boxes are indicated by an underline and the position of the VDRE is outlined by a box.

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BMC Genomics

ISSN: 1471-2164

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