Table 2 Module Membership Versus Epigenetic Variables
Source of Variation in kME | kMEblack, Total Prop Var Explained = 8.3% | kMEblue, Total Prop Var Explained = 4.2% | |||||
|---|---|---|---|---|---|---|---|
Source | Degrees Of Freedom | Sums of Sq | Prop. Of Total Var | p-value (F test) | Sums of Sq | Prop. Of Total Var | p-value (F-test) |
Histone Trimethylation (K4, K27, K4&K27, none) | 3 | 170.91 | 0.067 | < 2.2E-16 | 30.49 | 0.034 | < 2.2E-16 |
cMyc Complex | 1 | 39.21 | 0.015 | < 2.2E-16 | 1.48 | 0.002 | 2.6E-04 |
Oct4 Complex | 1 | 8.62 | 0.003 | 8.0E-08 | 0.79 | 0.001 | 7.5E-03 |
CPG class (HCP, ICP, LCP) | 2 | 4.56 | 0.002 | 4.9E-04 | 4.71 | 0.005 | 6.0E-10 |
PcG Bound | 1 | 0.88 | 0.000 | 8.7E-02 | 0.19 | 0.000 | 1.9E-01 |
CpG Methylated | 1 | 0.04 | 0.000 | 7.1E-01 | 0.58 | 0.001 | 2.2E-02 |
Residual Error | 7846 | 2353.8 | 0.917 | Â | 868.36 | 0.958 | Â |
Total Variation | 7855 | 2567.11 | Â | Â | 906.6 | Â | Â |
- This analysis of variance table reports which epigenetic variables and TF binding data have a significant effect on
(columns on the left hand side) and 
(columns on the right hand side). For each variable (source of variation), the columns report the degrees of freedom, the sums of squares, the proportion of total variance explained by the variable and the corresponding F-test p-value. Note that histone trimethylation status is the most significant source of variation for both and .
(columns on the left hand side) and 
(columns on the right hand side). For each variable (source of variation), the columns report the degrees of freedom, the sums of squares, the proportion of total variance explained by the variable and the corresponding F-test p-value. Note that histone trimethylation status is the most significant source of variation for both