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Table 2 Module Membership Versus Epigenetic Variables

From: Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells

Source of Variation in kME kMEblack, Total Prop Var Explained = 8.3% kMEblue, Total Prop Var Explained = 4.2%
Source Degrees Of Freedom Sums of Sq Prop. Of Total Var p-value (F test) Sums of Sq Prop. Of Total Var p-value (F-test)
Histone Trimethylation (K4, K27, K4&K27, none) 3 170.91 0.067 < 2.2E-16 30.49 0.034 < 2.2E-16
cMyc Complex 1 39.21 0.015 < 2.2E-16 1.48 0.002 2.6E-04
Oct4 Complex 1 8.62 0.003 8.0E-08 0.79 0.001 7.5E-03
CPG class (HCP, ICP, LCP) 2 4.56 0.002 4.9E-04 4.71 0.005 6.0E-10
PcG Bound 1 0.88 0.000 8.7E-02 0.19 0.000 1.9E-01
CpG Methylated 1 0.04 0.000 7.1E-01 0.58 0.001 2.2E-02
Residual Error 7846 2353.8 0.917   868.36 0.958  
Total Variation 7855 2567.11    906.6   
  1. This analysis of variance table reports which epigenetic variables and TF binding data have a significant effect on (columns on the left hand side) and (columns on the right hand side). For each variable (source of variation), the columns report the degrees of freedom, the sums of squares, the proportion of total variance explained by the variable and the corresponding F-test p-value. Note that histone trimethylation status is the most significant source of variation for both and .