Skip to main content

Table 2 MT Regulators and Associated Protein Profiles

From: Gene expression profiles in mouse embryo fibroblasts lacking stathmin, a microtubule regulatory protein, reveal changes in the expression of genes contributing to cell motility

Functional Class Common Name Gene Name Fold Change
MT Polymerization Regulators
  EB2 mapre2 1.20
  MAP1A mtap1 1.47
  MAP1B mtap1b 1.27
  MAP2 mtap2 -1.63
Stabilizers/Assembly Promoters MAP4 mtap4 1.24
  CLASP1 Clasp1 -1.19
  MACF2/BPAG1 Dst -1.29
  STOP mtap6 -1.16
  YB-1 Ybx1 -1.24
  Dia2 Diap2 -1.19
  RHAMM Hmmr -1.57
Mitosis-specific stabilizers TACC3 Tacc3 -1.17
  TPX2 Tpx2 -1.29
  SCG10 stmn2 -2.44
Destabilizers/Disassembly Promoters RB3 stmn4 2.26
  Kif2A Kif2a -1.22
  Kif18A Kif18a -1.62
MT Severing Proteins
  Katanin p60 katnal2 -1.37
  Fidgetin Fign -1.92
MT Nucleators
  gamma-tubulin 2 Tubg2 1.27
  GCP3 Tubgcp3 -1.18
MT-based Motors
  Kif11 Kif11 -1.24
  Kif15 Kif15 -1.45
  Kif18a Kif18a -1.62
  Kif1a Kif1a 1.77
  Kif20a Kif20a -1.15
  Kif21a Kif21a -1.74
Kinesins Kif21b Kif21b 4.60
  Kif22 Kif22 -1.19
  Kif26a Kif26a 2.32
  Kif26b Kif26b 3.24
  Kif2a Kif2a -1.22
  Kif4 Kif4 -1.27
  Kif9 Kif9 1.15
  dynein axonemal LC4 Dnalc4 1.26
  cytoplasmic dynein 1 IC1 Dync1i1 -1.29
Dyneins cytoplasmic dynein 1 LIC1 Dync1li1 -1.18
  cytoplasmic dynein 1 LIC2 Dync1li2 1.20
  dynein LC8-type2 Dynll2 -1.18
  1. Magnitude and direction of gene expression changes found using microarray analysis. Gene names are in M. musculus format, fold changes are from microarray data.