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Table 3 Pseudogenes shared between Paratyphi A and Typhi

From: Pseudogene accumulation in the evolutionary histories of Salmonella enterica serovars Paratyphi A and Typhi

Class

SSPA

STY

Gene

Gene product

Div.

i^

0062a

n/a

-

putative viral protein

-

i^

0255a

n/a

-

putative uncharacterized protein

-

i

1103

1362

-

Pertussis toxin subunit S1 related protein

1.22%

i^

1699a

0971

sopD2

*secreted effector protein SopD homolog

1.73%

i^

2014

0610

silA

*putative inner membrane proton/cation antiporter

1.08%

i^

2014a

0609a

cusS

*putative copper-ion sensor protein

0.18%

i^

3229

4202

-

putative phosphosugar-binding protein

0.14%

i

3640

3800

cdh

CDP-diacylglycerol pyrophosphatase

2.32%

i^

3888

4728a

-

putative uncharacterized protein

1.35%

i

30 transposase/phage genes and gene remnants, details available in Additional file 1

ii

0097

0113

-

*putative secreted protein

0.25%

ii

0431b

2631

-

putative IS transposase

0.24%

ii

0754a

2275

sopA

*secreted effector protein

0.23%

ii

3228

4203

-

putative L-asparaginase

0.14%

ii

3365a

4037

sugR

putative uncharacterized protein (SPI-3)

0.14%

iii

0192a

0218

fhuA

*ferrichrome-iron receptor precursor

23.95%

iii

0317a

2775

-

putative anaerobic dimethylsulfoxide reductase component

1.79%

iii

0329a

2762

sivH

*putative invasin (CS54)

1.17%

iii

0331a

2758

ratB

*putative lipoprotein (CS54)

1.67%

iii

0331b

2755

shdA

*putative uncharacterized protein (CS54)

2.11%

iii

0621a

2422

mglA

*galactoside transport ATP-binding protein

1.09%

iii

0720a

2311

wcaK

*putative extracellular polysaccharide biosynthesis protein

1.82%

iii

0756a

2268

yeeC

penicillin-binding protein

2.19%

iii

0850a

2166

fliB

lysine-N-methylase

3.11%

iii

0943a

1995

-

transposase

4.77%

iii

1014a

1913

hyaA

hydrogenase-1 small subunit

0.33%

iii

1220a

1508

-

*putative transport protein

1.31%

iii

1367a

1739

-

putative ribokinase (SPI-2)

1.42%

iii

1531a

1244

fhuE

*FhuE receptor precursor

0.96%

iii

1642a

1104

-

*putative secreted protein

1.54%

iii

1820a

0833

slrP

*secreted effector protein

1.95%

iii

2045a

0569

ybbW

*putative allantoin transporter

1.19%

iii

2301a

0333

safE

*probable lipoprotein (SPI-6 fimbrial cluster)

1.52%

iii

3388a

4007

-

putative cytoplasmic protein

1.12%

iii

3636a

3805

-

*putative permease of the Na+:galactoside symporter family

2.42%

iii

3828b

4503

dmsA

anaerobic dimethyl sulfoxide reductase chain A

0.22%

iii

3998a

4839

sefD

*putative fimbrial protein (SPI-10)

0.18%

iii, iv1

1197a

1486

narW

respiratory nitrate reductase 2 delta chain

1.74%

iii, iv2

2900a

3421

yhaO

*putative transport system protein

0.58%

iv3

0708

2328

wcaA

putative uncharacterized protein

1.35%

  1. (i) Ancestral pseudogenes (shared by virtue of inheritance in inactived gene from a common ancestor); ^ intact in Typhimurium, note that 30 ancestral pseudogenes encoding phage or transposase genes are excluded here but listed in Additional file 1. (ii) Recombined pseudogenes (shared by recombination). (iii) Recent conserved pseudogenes (independent inactivating mutations in each serovar). (iv) Recent strain-specific pseudogenes (pseudogenes in some but not all strains belonging to their respective serovar); 1pseudogene in Paratyphi A (both strains) and Typhi Ty2, 2pseudogene in Typhi (both strains) and Paratyphi A ATCC9150, 3pseudogene in Paratyphi A ATCC9150 and Typhi CT18. SSPA and STY -systematic identifiers in Paratyphi A AKU_12601 and Typhi CT18 respectively; n/a – not annotated. For genes lying in Salmonella pathogenicity islands (SPIs) the island is indicated in brackets after the gene product. Div. – nucleotide divergence reported in [15].