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Figure 2 | BMC Genomics

Figure 2

From: Identification of novel endogenous antisense transcripts by DNA microarray analysis targeting complementary strand of annotated genes

Figure 2

Schematic illustration of the strategy to discover novel conserved NATs. Conserved NATs were previously listed according to the presence of cDNA within humans and mice (A). Black and grey boxes denote transcribed region identified by cDNA on plus and minus strand of the genome, respectively. Black triangles indicate microarray probes designed within the transcribed regions. If antisense counterpart on opposite strand has not been overlapped, or not been identified in mice (B and C), microarray probes attempted to detect antisense expression could not be designed. To discover novel conserved NAT, we designed AFAS probes (red triangles) for mouse genes for which the orthologous partner in the human genome has an antisense counterpart.

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BMC Genomics

ISSN: 1471-2164

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