Table 2 Conserved correlated genes are associated with various types of cancer and neurological disorders.
Disease | Associated genes | References |
|---|---|---|
Schizophrenia | BDNF RGS4 NR4A2 | Schmidt-Kastner et al. (2006) |
Parkinson's disease | BDNF PTGS2 SNCA NR4A2 | Murer et al. (2001) Chae et al. (2008) Pardo and van Duijn (2005) |
Alzheimer's | BDNF KALRN | Murer et al. (2001) Youn et al. (2007) |
Polyglutamine neurodegeneration | NEFL BAIAP2 | Mosaheb et al. (2005) Thomas et al. (2001) |
alpha-mannosidosis | MAN1A1 | D'Hooge et al. (2005) |
Ophthalmopathy | CYR61 DUSP1 EGR1 PTGS2 | Lantz et al. (2005) |
Epilepsy | BDNF DUSP6 EGR1 | Binder and Scharfman (2004) Rakhade et al. (2007) |
Depression | BDNF DUSP1 | Russo-Neustadt and Chen (2005) Rakhade et al. (2007) |
Ischemia | BDNF CD44 PTGS2 | Binder and Scharfman (2004) Murphy et al. (2005) |
Ovarian carcinoma | BDNF ITF2 DUSP1 RGS4 | Yu et al. (2008) Kolligs et al. (2002) Puiffe et al. (2007) |
Breast cancer | BDNF FGFR1 CCND2 PLAU SERPINE1 PLAUR MAZ DUSP6 EGR1 KFL10 PTRF | Tozlu et al. (2006) Koziczak et al. (2004) Grebenchtchikov et al. (2005) Cui et al. (2006) Liu et al. (2007) Reinholz et al. (2004) Levea et al. (2000) |
Lung cancer | BDNF ODZ2 CCND2 GFI1 | Ricci et al. (2005) Kan et al. (2006) |
Prostate cancer | BDNF IGFBP5 PLAUR p75NTR | Bronzetti et al. (2008) Nalbandian et al. (2005) |
Pheochromocytoma | PCSK1 PCSK2 SCG2 | Guillemot et al. (2006) |
Endometrial cancer | CXCL5 OLFM1 | Wong et al. (2007) |
Leukemia | PKCB1 CCND2 | Hans et al. (2005) |