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Table 2 Effects of polymorphisms in the bovine SPP1 gene on EBVs for SCS for the first, second, third, and over all lactations.

From: Osteopontin: an early innate immune marker of Escherichia coli mastitis harbors genetic polymorphisms with possible links with resistance to mastitis

SNP

Least squares meana

  

(± SEM)a

P value

SPP1c.-1301G>A

GG

GA

AA

  

SCS

2.98b

3.16c

3.38c

(± 0.14)

<.001

SCS1

2.98b

3.10c

3.25b, c

(± 0.13)

<.001

SCS2

2.96b

3.14c

3.39c

(± 0.15)

<.001

SCS3

2.99b

3.16c

3.50c

(± 0.16)

<.001

SPP1c.-1251C>T

CC

CT

TT

  

SCS

3.04

2.97

3.02

(± 0.06)

0.067

SCS1

3.02

2.98

3.02

(± 0.05)

0.446

SCS2

3.03

2.96

3.00

(± 0.06)

0.155

SCS3

3.06b

2.97c

3.01b, c

(± 0.07)

0.057

SPP1c.-430G>A

GG

GA

AA

  

SCS

3.04

2.97

3.02

(± 0.06)

0.067

SCS1

3.02

2.98

3.02

(± 0.05)

0.446

SCS2

3.03

2.96

3.00

(± 0.06)

0.155

SCS3

3.06b

2.97c

3.01b, c

(± 0.07)

0.057

SPP1c.*40A>C

AA

AC

CC

  

SCS

3.06b

2.97c

2.98b, c

(± 0.05)

0.004

SCS1

3.03

2.98

2.98

(± 0.05)

0.183

SCS2

3.05b

2.95c

2.97b, c

(± 0.05)

0.014

SCS3

3.09b

2.97c

2.97b, c

(± 0.06)

0.004

  1. a The least square means are the adjusted means of the EBVs for the SCS for bulls which are grouped by genotype for each SNP and calculated for the respective lactation (over all, first, second or third lactations). SEM standard error of the mean.
  2. b, c Means (within a line) without a common superscript letter differ from each other at the 5% level of significance.