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Table 6 Estimated haplotype frequencies and effects of haplotypes in the bovine SPP1 gene on EBVs for SCSa and for production traits.

From: Osteopontin: an early innate immune marker of Escherichia coli mastitis harbors genetic polymorphisms with possible links with resistance to mastitis

Genotype   Least squares mean
Allele 1 Allele 2 Frequency (%) SCS SCS1 SCS2 SCS3 Milk yield (Kg) Fat yield (Kg) Protein yield (Kg) Fat % Protein %
H4 (GCGC) H4 (GCGC) 2 (0.4) 2.81 2.9 2.74 2.79 -594 0 -17 0.22 0.02
H1 (GCGA) H4 (GCGC) 30 (5.2) 2.87 2.90 2.85 2.88 -238 -6 -3 0.03 0.04
H2 (GTAC) H4 (GCGC) 13 (2.2) 2.88 2.88 2.92 2.88 -333 -8 -8 0.04 0.03
H1 (GCGA) H2 (GTAC) 170 (29.4) 2.94 2.96 2.92 2.94 -128 1 -0.7 0.07 0.04
H3 (ACGA) H4 (GCGC) 5 (0.9) 3.01 3.04 3.03 2.96 296 25 8 0.15 -0.01
H1 (GCGA) H1 (GCGA) 205 (35.6) 3.02 3.00 3.01 3.05 42 -2 1 -0.02 0.001
H2 (GTAC) H2 (GTAC) 37 (6.4) 3.02 3.02 3.00 3.01 -99 -13 -2 -0.09 0.02
H4 (GCGC) H5 (GTAA) 6 (1.0) 3.03 3.01 3.03 3.05 -244 4 -8 0.14 0.005
H1 (GCGA) H3 (ACGA) 76 (13.2) 3.16 3.09 3.13 3.17 -139 2 0.1 0.07 0.05
H2 (GTAC) H3 (ACGA) 28 (4.8) 3.17 3.15 3.18 3.2 -198 -7 -2 0.01 0.04
H3 (ACGA) H3 (ACGA) 6 (1.0) 3.38 3.25 3.39 3.50 -517 -11 -10 0.08 0.07
   ± SEM ± 0.24 ± 0.22 ± 0.26 ± 0.28 ± 567 ± 19 16 ± 0.21 ± 0.08
   P value <.001 0.012 <.001 <.001 0.236 0.044 0.745 0.043 0.078
  1. a EBVs are calculated for the respective lactation: over all (SCS), first (SCS1), second (SCS2), and third (SCS3) lactations